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Malaise is a feeling of being unwell, having general discomfort, uneasiness in one's bodily health or having pain, overall weakness, and is often the first indication of an infection or the onset of an illness or disease.[1][2][3][4]

ME/CFS patients have an almost continuous feeling of malaise and this and other symptoms can worsen upon exertion leading to post-exertional malaise (PEM), the hallmark symptom of ME/CFS.

Malaise in ME/CFS[edit | edit source]

Malaise is a general feeling of being unwell which can be almost constant if not constant in ME/CFS depending upon the patient's disease severity. There are many symptoms experienced by patients often associated with malaise, each waxing and waning and with differing severity. These malaise and other ME/CFS disease symptoms will worsen and increase in number upon exertion due to PEM.[5]

Cause[edit | edit source]

There are many possible causes of malaise. A cold, influenza, and swine flu; hypoglycemia common in diabetes; strep throat; sinus infections; bronchitis; hepatitis; shingles; malaria; lupus; obstructive uropathy; HIV/AIDS; dengue hemorrhagic fever; ebola; chronic fatigue syndrome; neutropenia (low white blood cells); necrotizing fasciitis (soft tissue inflammation); lyme disease; encephalitis; chronic kidney diseas; pyelonephritis; non-Hodgkin's lymphoma; infectious mononucleosis; bone infection; chickenpox; walking pneumonia (atypical pneumonia); and cellulitis, to name just a few.[3]

Symptoms[edit | edit source]

Depending on the underlying cause, different symptoms can occur.

Physical symptoms affecting the body

Other symptoms that may occur along with malaise such as those related to emotional or psychological disturbance

Serious symptoms that might indicate a life-threatening condition

  • Chest pain or pressure
  • Difficulty breathing
  • High fever (higher than 101 degrees Fahrenheit)
  • Inability to eat or drink
  • Paralysis
  • Severe abdominal pain or cramping[6]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. "Malaise - Symptoms, Causes, Treatments". Jun 26, 2014. Retrieved Oct 12, 2018. 
  2. "malaise". The Free Dictionary. 
  3. 3.03.1 "Malaise: Causes, Symptoms and Diagnosis". Retrieved Oct 12, 2018. 
  4. Dr. Chris. "Malaise (Sick Feeling) Meaning, Causes and Symptoms |". Retrieved Oct 12, 2018. 
  5. Jason, Leonard A.; Evans, Meredyth; So, Suzanna; Scott, Jilian; Brown, Abigail (Jan 2, 2015). "Problems in Defining Post-Exertional Malaise". Journal of Prevention & Intervention in the Community. 43 (1): 20–31. doi:10.1080/10852352.2014.973239. ISSN 1085-2352. PMC 4295644Freely accessible. PMID 25584525. 
  6. "Malaise - Symptoms, Causes, Treatments". Health Grades. Jun 26, 2014. p. 2. Retrieved Oct 12, 2018. 

post-exertional malaise (PEM) - A notable exacerbation of symptoms brought on by small physical or cognitive exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others.

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

hypoglycemia - abnormal decrease of sugar in the blood

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.