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Lymphotoxin-alpha or LTA or Tumor necrosis factor beta or TNF-beta gene encodes a cytokine that is produced by Th1 cells, CD8+ T cells, natural killer (NK) cells, B cells, and macrophages.
Alternative names for lymphotoxin-alpha include:
- Tumor Necrosis Factor Ligand Superfamily Member 1
- Tumor Necrosis Factor Ligand 1E
- TNF Superfamily, Member 1
Function[edit | edit source]
The protein encoded by LTA is involved in many inflammatory, immunostimulatory, and antiviral responses.
LTA gene variants have been linked to susceptibility to leprosy type 4, myocardial infarction (heart attacks), non-Hodgkin's lymphoma, and psoriatic arthritis.
ME/CFS[edit | edit source]
Notable studies[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
- LT-Alpha - Genecards
References[edit | edit source]
- ↑ Calmon-Hamaty, Flavia; Combe, Bernard; Hahne, Michael; Morel, Jacques (2011). "Lymphotoxin α revisited: general features and implications in rheumatoid arthritis". Arthritis Research & Therapy. 13 (4): 232. doi:10.1186/ar3376. ISSN 1478-6354. PMC 3239340. PMID 21861866.
- ↑ 2.02.12.22.3 "LT-Alpha Gene card". Gene cards. Retrieved March 18, 2022.
β β / Β. Greek letter beta (a symbol used in science), equivalent to "b".
The information provided at this site is not intended to diagnose or treat any illness.
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