Interleukin 7 receptor

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The interleukin 7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - i.e. it is a heterodimer, and consists of two subunits, interleukin 7 receptor (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various cytokines, including interleukin-2, interleukin 4, interleukin 9, and interleukin 15. Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others.[citation needed]


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A study by Griffith University found that CD8+ T cells exhibited significantly decreased CD127 and PSGL-1[1]

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α α / Α. Greek letter alpha or alfa (a symbol used in science), equivalent to "a".

γ γ / Γ. Greek letter gamma/gamme (a symbol used in science), third letter of the Greek alphabet. Equivalent to the letter "g".

cytokine any class of immunoregulatory proteins secreted by cells, especially immune cells. Cytokines are small proteins important in cell signaling that modulate the immune system. (Learn more: me-pedia.org)

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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.