Interleukin 7 receptor

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The interleukin-7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - i.e. it is a heterodimer, and consists of two subunits, interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various cytokines, including interleukin-2, -4, -9, and -15. Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others.


ME/CFS[edit]

A study by Griffith University found that CD8+ T cells exhibited significantly decreased CD127 and PSGL-1[1]



Learn more[edit]

References[edit]

<references>
  1. A Preliminary Comparative Assessment of the Role of CD8+ T Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis’., Journal of Immunology Research, Volume 2016 (2016), Article ID 9064529, 8 pages


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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history