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IP-10 is Interferon gamma (INF-γ) inducible protein 10.[1] It is a chemokine, and important for recruiting natural killer cells to the myocardium, and for limiting viral duplication in murine (mice/rodent) coxsackievirus infection.[2]

Alternative names[edit | edit source]

IP-10 is also known as:

Notable studies[edit | edit source]

  • 2017 - The Role of IP-10 in Chronic Fatigue Syndrome[4]
This study found "compelling evidence" of the role of several cytokines/[]chemokine]]s in the physiological and cognitive pathology in a group of patients with chronic fatigue syndrome, although these patients were selected using the Oxford criteria, which includes many patients with chronic fatigue not caused by ME/CFS.

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. "CXCL10 - C-X-C motif chemokine 10 precursor - Homo sapiens (Human) - CXCL10 gene & protein". www.uniprot.org. Retrieved Jan 24, 2019. 
  2. 2.02.1 Loux, Tara J.; Lotze, Michael T.; Zeh, Herbert J. (Jan 1, 2010). Lotze, Michael T.; Thomson, Angus W., eds. "Chapter Fourteen - NK cells as recipients of cytokine signals". San Diego: Academic Press: 189–201. ISBN 9780123704542. 
  3. Lee, James J.; Rosenberg, Helene F., eds. (Jan 1, 2013). "Chapter 6 - Eosinophil Trafficking". Eosinophils in Health and Disease. Boston: Academic Press: 121–166. ISBN 9780123943859. 
  4. McArdle, Anne; Gusnanto, Arief; Earl, Kate; Sakellariou, George; Lawton, Clare; Owens, Daniel; Close, Graeme; Beadsworth, Michael; Dye, Louise (Apr 1, 2017). "The role of IP-10 in Chronic Fatigue Syndrome". The FASEB Journal. 1 (1_supplement): lb789. doi:10.1096/fasebj.31.1_supplement.lb789. 

chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue (idiopathic chronic fatigue) without additional symptoms. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.