Herpesviruses

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Herpesviruses are a family of DNA viruses with extremely high prevalence rates.

Types[edit]

Viruses in this family include HSV-1 and HSV-2, Epstein-Barr virus (HHV4), which causes mononucleosis, Varicella zoster virus, which causes chickenpox and shingles. More than 90% of adults have been infected with at least one of these viruses.

Other herpesviruses include human cytomegalovirus, HHV-6, HHV-7, and Kaposi's sarcoma-associated herpesvirus.

Latency[edit]

They share in common that after the initial infection, these viruses usually remain latent for life.[1]

Reactivation[edit]

Reactivation of these viruses have been associated with a number of diseases.[2] HSV-1 has been implicated in Alzheimer's.[3]

Several of these viruses have transactivating potential.[1]

Chronic fatigue syndrome[edit]

It is unclear whether herpesviruses associated with Chronic fatigue syndrome play an etiological role or are "bystanders" – opportunistic reactivations under a state of immune dysregulation.

Studies related to Herpesviruses and ME/CFS[edit]

Learn more[edit]

See also[edit]

References[edit]

  1. 1.0 1.1 De Bolle, Leen; Naesens, Lieve (Jan 2005), "Update on Human Herpesvirus 6 Biology, Clinical Features, and Therapy", Clin Microbiol Rev, 8 (1): 217–245, doi:10.1128/CMR.18.1.217-245.200 
  2. Reference needed.
  3. Experts Say There’s a Herpes-Alzheimer’s Link, Time, March 10, 2016
  4. Williams, Marshall V.; Cox, Brandon; Ariza, Maria Eugenia (2017), "Herpesviruses dUTPases: A New Family of Pathogen-Associated Molecular Pattern (PAMP) Proteins with Implications for Human Disease", Pathogens, 6 (1): 2, doi:10.3390/pathogens6010002 


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history