Graded exercise therapy

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Graded exercise therapy (GET) is a form of physical therapy for the management of chronic fatigue syndrome where physical activity is gradually increased over time. It is a treatment offered to ME/CFS patients in the UK by the National Health Service (NHS) as specified in the NICE guidelines.

Patient Analysis of PACE Results[edit]

Graham McPhee and others created videos investigating the PACE trial data in relation to Graded Exercise Therapy.[1][2]

Fear of exercise[edit]

The PACE trial investigators have stated that they believe a causal factor of the persistence of ME/CFS is fear of exercise.[3] This claim as been criticized as unsupported by trial results.[4]


Notable studies[edit]

Centers for Disease Control[edit]

July 2017, the CDC's Chronic Fatigue Syndrome page has been changed to Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and GET and CBT recomendations have been removed.[7][8]

Learn more[edit]

See also[edit]


  1. "PACEindividuals"
  2. "PACEgraph"
  3. Tackling fear about exercise produces long term benefit in chronic fatigue syndrome
  4. Objective measures found a lack of improvement for CBT & GET in the PACE Trial: subjective improvements may simply represent response biases or placebo effects in this non-blinded trial
  6. The Media and ME
  7. Trial By Error: The CDC Drops CBT/GET - Virology Blog
  8. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history