File:CFS-ANS-immune.png

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Summary[edit | edit source]

Chronic Fatigue Syndrome: interactions between the autonomic nervous system, immune system and HPA axis.

Interactions between the ANS, immune system and HPA axis in CFS. Edge shade is related to MI between nodes. Darker edges indicate a stronger link. Abbreviations

  • AUCg- Area under the curve with respect to ground
  • BEI- Baroreflex effectiveness index
  • BPV- Blood pressure variability
  • CFQ- Total Cognitive Failures Questionnaire score
  • DEX10- in vitro glucocorticoid receptor response to 10% dexamethasone solution
  • DEX100- in vitro glucocorticoid receptor response to 100% dexamethasone solution
  • EF- Ejection fraction
  • HRV- Heart rate variability
  • LPS- in vitro glucocorticoid receptor response to lipopolysaccharide
  • MASS- End diastolic wall mass, Null, in vitro glucocorticoid receptor response without stimulation
  • SBPa- Mean systolic blood pressure during active stand
  • SV- Stroke volume

Author[edit | edit source]

Clark JE, Ng W-F, Rushton S, Watson S, Newton JL (2019) Network structure underpinning (dys)homeostasis in chronic fatigue syndrome; Preliminary findings. PLoS ONE 14(3): e0213724. doi:10.1371/journal.pone.0213724

Source[edit | edit source]

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213724 CC BY attribution license

Other information: Figure 3

Licensing[edit | edit source]

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See also[edit | edit source]

cognition Thought processes, including attention, reasoning, and memory.

heart rate variability (HRV) - A measurement of the variability of the heart rate over time. When the heart rate is consistent, there will be a low heart rate variability. When the heart rate is constantly changing, there will be a high heart rate variability. Heart rate variability is often used by ME/CFS patients to monitor their autonomic nervous system, as high heart rate variability is associated with the sympathetic nervous system and low heart rate variability is associated with the parasympathetic nervous system.

heart rate variability (HRV) - A measurement of the variability of the heart rate over time. When the heart rate is consistent, there will be a low heart rate variability. When the heart rate is constantly changing, there will be a high heart rate variability. Heart rate variability is often used by ME/CFS patients to monitor their autonomic nervous system, as high heart rate variability is associated with the sympathetic nervous system and low heart rate variability is associated with the parasympathetic nervous system.

homeostasis the maintenance of stable internal biological conditions (e.g. body temperature) in a changable environmen

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current16:53, November 9, 2019Thumbnail for version as of 16:53, November 9, 20191,756 × 1,872 (1.37 MB)Notjusttired (talk | contribs)Chronic Fatigue Syndrome: interactions between the autonomic nervous system, immune system and HPA axis. Interactions between the ANS, immune system and HPA axis in CFS. Edge shade is related to MI between nodes. Darker edges indicate a st...

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