Digestive problems are common in ME/CFS. These include abdominal pain, constipation, cough, development of allergies and intolerances (including alcohol intolerance and food sensitivities), diarrhea, dysbiosis, dysphagia, dyspepsia, esophageal spasms, gas, heartburn, IBS, increased appetite, leaky gut, loss of appetite, nausea, reflux, SIBO, sore throat, and tenesmus.
- 81.8% - 85.6% of the 2073 patients in a Belgian study of 2001 reported gastrointestinal disturbance.
- De Becker, P; McGregor, N; De Meirleir, K (Sep 2001), "A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome.", Journal of Internal Medicine, 250 (3): 234-240, PMID 11555128