Dehydroepiandrosterone (DHEA) is a steroid hormone. It is the most abundant circulating steroid hormone in humans, produced in the adrenal glands, gonads and the brain, where it functions as an intermediate in the synthesis of androgen and estrogen sex steroids.
In mice, DHEA is protective against a variety of infections including Coxsackie B4, herpes simplex virus type 2. 
- ↑ Loria, R. M.; Padgett, D. A.; Huynh, P. N. (September 1996), "Regulation of the immune response by dehydroepiandrosterone and its metabolites", The Journal of Endocrinology, 150 Suppl: –209–220, ISSN 0022-0795, PMID 8943803
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