Daehyun Jo

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Daehyun Jo, MD, PhD, specializes in Anesthesiology and Pain Medicine, in South Korea. From 2008–2010, he was an Adjunctive Professor in Department of Anesthesiology and Pain Medicine, College of Medicine, University of Utah, USA. [1]

Dr. Jo is one of the authors of the 2011 case definition, International Consensus Criteria.[2]

Notable studies[edit]

  • 2017, Pulsed Radiofrequency to the Dorsal Root Ganglion in Acute Herpes Zoster and Postherpetic Neuralgia: Retrospective Study
    "Abstract - BACKGROUND: Latent varicella zoster virus reactivates mainly in sensory ganglia such as the dorsal root ganglion (DRG) or trigeminal ganglion. The DRG contains many receptor channels and is an important region for pain signal transduction. Sustained abnormal electrical activity to the spinal cord via the DRG in acute herpes zoster can result in neuropathic conditions such as postherpetic neuralgia (PHN). Although the efficacy of pulsed radiofrequency (PRF) application to the DRG in various pain conditions has been previously reported, the application of PRF to the DRG in patients with herpes zoster has not yet been studied.vOBJECTIVES: The aim of the present study was to compare the clinical effects of PRF to the DRG in patients with herpes zoster to those of PRF to the DRG in patients with PHN. STUDY DESIGN: Retrospective comparative study. SETTING: University hospital pain center in Korea. METHODS: The medical records of 58 patients who underwent PRF to the DRG due to zoster related pain (herpes zoster or PHN) were retrospectively analyzed. Patients were divided into 2 groups according to the timing of PRF after zoster onset: an early PRF group (within 90 days) and a PHN PRF group (more than 90 days). The efficacy of PRF was assessed by a numeric rating scale (NRS) and by recording patient medication doses before PRF and at one week, 4 weeks, 8 weeks, and 12 weeks after PRF. RESULTS: Pain intensity was decreased after PRF in all participants. However, the degree of pain reduction was significantly higher in the early PRF group. Moreover, more patients discontinued their medication in the early PRF group, and the PRF success rate was also higher in the early PRF group. LIMITATIONS: The relatively small sample size from a single center, short duration of review of medical records, and the retrospective nature of the study. CONCLUSIONS: PRF to the DRG is a useful treatment for treatment-resistant cases of herpes zoster and PHN. Particularly in herpes zoster patients with intractable pain, application of PRF to the DRG should be considered for pain control and prevention of PHN."[3]
  • 2010, A novel approach to studying the sensory pathways involved in the perception of fatigue
    "Abstract-Debilitating fatigue is common in cancer, multiple sclerosis, fibromyalgia, and chronic fatigue syndrome. However, the mechanisms of sensory muscle fatigue signaling are unknown. In mice, 2 populations of muscle afferents signal noxious and nonnoxious metabolite levels, respectively. These afferents use a combination of ASIC, P2X, and TRPV1 receptors to detect the unique metabolites (protons, adenosine triphosphate [ATP], and lactate) produced by exercise. Our objective was to develop a method to directly infuse protons, ATP, and lactate into thenar muscles in healthy subjects to verify that human sensory neurons use similar molecular receptors to detect the metabolites produced by muscle contraction."[4]

Learn more[edit]

See also[edit]

References[edit]

  1. http://www.spinemeeting.org/data/cv/ICSP2016_CV_Daehyun%20Jo.pdf
  2. Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, A C P; Speight, N; Vallings, R; Bateman, L; Baumgarten-Austrheim, B; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Jo, D; Lewis, D; Light, A; Marshall-Gradisnik, S; Mena, I; Mikovits, JA; Miwa, K; Murovska, M; Pall, ML; Stevens, S (2011), "Myalgic encephalomyelitis: International Consensus Criteria.", Journal of Internal Medicine, 270 (4): 327-38, PMID 21777306, doi:10.1111/j.1365-2796.2011.02428.x 
  3. Koohyun Kim, MD, Daehyun Jo, MD, PhD, and EungDon Kim, MD. (2017). Pulsed Radiofrequency to the Dorsal Root Ganglion in Acute Herpes Zoster and Postherpetic Neuralgia: Retrospective Study. Pain Physician Journal, Vol 20, Issue 3, pp. E411-E418. PMID: 28339440
  4. Kelly Pollak, MD, Daehyun Jo, MD, Timothy Vanhaitsma, Ron Hughen, Alan Light, PhD. (2010). A novel approach to studying the sensory pathways involved in the perception of fatigue. Journal of Critical Care. Volume 25, Issue 4, Page e18. http://dx.doi.org/10.1016/j.jcrc.2010.08.023


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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history