D-Ribose

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Ribose is a carbohydrate with the formula C5H10O5, that exists in two forms: D-ribose, which occurs in nature and L-ribose, which is the mirror image of D-ribose and does not occur in nature.[1]

D-ribose is a building block used by the cells in one of the chemical pathways that makes the energy molecule, ATP.[2]

D-ribose comes in powder form, tastes sweet, and can used as a sugar substitute in drinks or on cereal.

Use in ME/CFS and FM[edit]

It is used as a supplement for help boost muscle energy, such as for athletes and people with ME/CFS, Fibromyalgia, and coronary artery disease.[3] The theory is that if one supplies the body with the precursors to ATP, then it will be easier for the body to make ATP.[2]

Sources[edit]

Supplemental d-ribose is manufactured from corn, so is to be avoided by those with corn allergies or insensitivities.[2]

Evidence[edit]

A small study of 41 patients by Jacob Teitelbaum resulted in: "Approximately 66% of patients experienced significant improvement while on D-ribose [at a dose of 5 g, three times a day], with an average increase in energy on the VAS [visual analog scale categories: energy; sleep; mental clarity; and pain intensity] of 45% and an average improvement in overall well-being of 30% (p < 0.0001)." The study authors concluded that "D-ribose significantly reduced clinical symptoms in patients suffering from fibromyalgia and chronic fatigue syndrome".[4]

Learn more[edit]

See also[edit]

Muscle fatigability

References[edit]

  1. Wikipedia - Ribose
  2. 2.0 2.1 2.2 Doctor Myhill - D-ribose
  3. WebMD - Vitamins and Supplements - Ribose
  4. Teitelbaum, Jacob E.; Johnson, Clarence; St Cyr, John (November 2006), "The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study", Journal of Alternative and Complementary Medicine (New York, N.Y.), 12 (9): 857–862, ISSN 1075-5535, PMID 17109576, doi:10.1089/acm.2006.12.857 


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history