In mouse models, Ampligen was found to be protective of Coxsackie B3-induced myocarditis.
Selenium deficiency increases the virulence of Coxsackie B3 infections in a mouse model.
Coxsackievirus B3 cleaves Mitochondrial Antiviral Signaling (MAVS) protein to inhibit type I interferon induction. Conversely, upregulation of MAVS inhibits coxsackie B3 by increasing type-1 interferon production.
- ↑ http://www.ncbi.nlm.nih.gov/pubmed/14693549
- ↑ http://jn.nutrition.org/content/130/2/485S.full
- ↑ http://www.ncbi.nlm.nih.gov/pubmed/21436888?dopt=Abstract
- ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546859/
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