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The co-conditioning theory of ME/CFS was first proposed in 2010 and is biopsychosocial-based theory. Co-conditioning is proposed to cause chronic fatigue syndrome as follows: "after repetitive overwork and/or stress, alarm signal to rest and fatigue sensation may cause in response to an unconditioned stimulus (impaired homeostasis and function) that has been paired with a conditioned stimulus (overwork and/or stress)".
Theory[edit | edit source]
Evidence[edit | edit source]
Treatment[edit | edit source]
A re-co-conditioning treatment is proposed, including cognitive behavioral therapy for "stress, stress responses, overwork, inactivity, and the psychological responses as a result of the familial, social, economic, and educational handicaps" combined with medication to reduce symptoms and restore homeostasis.
See also[edit | edit source]
- Medical hypotheses (category)
Learn more[edit | edit source]
References[edit | edit source]
- ↑ 1.01.11.21.3 Tanaka, Masaaki; Watanabe, Yasuyoshi (August 2010). "A new hypothesis of chronic fatigue syndrome: Co-conditioning theory". Medical Hypotheses. 75 (2): 244–249. doi:10.1016/j.mehy.2010.02.032. ISSN 0306-9877.
cognitive behavioral therapy (CBT) - A type of psychotherapy geared toward modifying alleged unhealthy thinking, behaviors or illness beliefs. One of the treatment arms used in the controversial PACE trial.
homeostasis the maintenance of stable internal biological conditions (e.g. body temperature) in a changable environmen
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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.