Chlamydia pneumoniae

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Jump to: navigation, search

Chlamydia pneumoniae (also referred to as Chlamydophila pneumoniae or CPN) is an intracellular bacterium of the species Chlamydophila, and can infect people via airborne transmission. It is a major cause of community-acquired pneumonia.[1] It has been implicated as a potential cause of ME/CFS in a subset of patients. A study by Chia & Chia found that 10% of their patients had a chlamydophila pneumoniae infection which may have caused or contributed to their ME/CFS.[2]

A chronic chlamydophila pneumoniae infection can be treated with antibiotics.[3]

Testing[edit | edit source]

Accurately testing for chlamydia pneumoniae can be difficult, therefore, a negative blood test may not mean you do not have an infection. Additionally, there is a general shortage worldwide of facilities which can identify/diagnose Chlamydia pneumoniae.[4] Common tests for chlamydophila pneumoniae include the microimmunofluorescence (MIF) test[5] or via biopsy.

Dr. John Chia notes that most ME/CFS patients with active Chlamydia pneumoniae infection will have high IgG antibody levels (but IgM is negative). Dr. Chia has treated patients with titers as low as 1:128.[6]

Treatment[edit | edit source]

A chlamydophila pneumoniae infection, while an uncommon cause of ME/CFS, is one of the more treatable forms. Antibiotic treatment with azithromycin or rifampin can therefore improve or even cure patients. Chia & Chia found that while antibiotic treatment was successful in many patients, relapse was also common.[2] Some patients have reported recovery after being treated with Dr Stratton's original protocol[7]. More information on treatment options can be found on CPN Help's Treatment Protocols page[8].

Notable studies[edit | edit source]

  • 1999, Chronic Chlamydia pneumoniae Infection: A Treatable Cause of Chronic Fatigue Syndrome[9] - (Article)
  • 2003, Multiple co-infections (Mycoplasma, Chlamydia, human herpes virus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms[10] - (Abstract)

Learn more[edit | edit source]

References[edit | edit source]

  1. Chlamydia pneumoniae not caught like you thought
  2. 2.02.1 Chia, J. K.; Chia, L. Y. (Aug 1999). "Chronic Chlamydia pneumoniae infection: a treatable cause of chronic fatigue syndrome". Clinical Infectious Diseases. 29 (2): 452–453. doi:10.1086/520239. ISSN 1058-4838. PMID 10476765. 
  3. Tovey, John E. (Oct 2007). "Chlamydia pneumoniae infection a treatable cause of Chronic Fatigue Syndrome". BMJ. 
  4. "Diagnosis Issues | Cpnhelp.org". cpnhelp.org. Retrieved Jan 28, 2020. 
  5. Wang, San-pin (Jun 2000). "The Microimmunofluorescence Test for Chlamydia pneumoniae Infection: Technique and Interpretation". The Journal of Infectious Diseases. 181 (Supplement 3): S421–S425. doi:10.1086/315622. 
  6. Chia, John (Aug 29, 1999). "Chronic Chlamydia pneumoniae Infection: A Treatable Cause of Chronic Fatigue Syndrome" (PDF). 
  7. "Astrodiana's story: Cure from Chronic Fatigue Syndrome with Dr. Stratton's original protocol | Cpnhelp.org". cpnhelp.org. Retrieved Jan 28, 2020. 
  8. "Treatment Protocols | Cpnhelp.org". cpnhelp.org. Retrieved Jan 28, 2020. 
  9. Chia, John K. S.; Chia, Laura Y. (Aug 1999). "Chronic Chlamydia pneumoniae Infection: A Treatable Cause of Chronic Fatigue Syndrome". Clinical Infectious Diseases. 29 (2): 452–453. doi:10.1086/520239. ISSN 1058-4838. 
  10. Nicolson, G. L.; Gan, R.; Haier, J. (May 2003). "Multiple co-infections (Mycoplasma, Chlamydia, human herpes virus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms". APMIS: acta pathologica, microbiologica, et immunologica Scandinavica. 111 (5): 557–566. doi:10.1034/j.1600-0463.2003.1110504.x. ISSN 0903-4641. PMID 12887507. 

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

antibody - Antibodies or immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.