A 2016 study in the Netherlands was the first to use contrast-enhanced cardiac magnetic resonance (CMR) imaging in assessing cardiac involvement in women who have CFS. Twelve women were recruited from a specialised CFS centre who had a diagnosis of CFS based on the Fukuda criteria. Thirty-six age- and gender-matched controls, also, were included. The conclusions were that in patients with CFS, cardiac magnetic resonance demonstrated lower left ventricle dimensions and a mildly reduced left ventricle function. Heart wall motion abnormalities and the presence of myocardial fibrosis were observed in some CFS patients.
Reduced cardiac volumes have been associated with blood volume, but not length of disease.
A study found that blood volume is a strong physiological correlate of peak oxygen consumption in patients with CFS.
CFS patients have several risk factors for heart disease.
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