Borrelia burgdorferi

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Borrelia burgdorferi, defined by the NIH, "is a tick-borne obligate parasite whose normal reservoir is a variety of small mammals. Whereas infection of these natural hosts does not lead to disease, infection of humans can result in Lyme disease, as a consequence of the human immunopathological response to B. burgdorferi."[1]

Immune response[edit]

It is recognized by toll-like receptors 1 and 2. Mutations in TLR1 are associated with heightened Th1 inflammatory responses and antibiotic-refractory Lyme arthritis[2]

References[edit]

  1. Biology of Infection with Borrelia burgdorferi NCBI - NIH - Borrelia burgdorferi
  2. http://www.ncbi.nlm.nih.gov/pubmed/22246581


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history