Tyrosine
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Tyrosine, an amino acid, is a precursor to the neurotransmitter dopamine. It is converted to L-DOPA by the enzyme tyrosine hydroxylase.[citation needed]
It is also a precursor to the thyroid hormones triiodothyronine (T3) and thyroxine (T4)
Tyrosine and its precursor phenylalanine are required for the synthesis of coenzyme Q10
ME/CFS[edit | edit source]
Reduced levels of plasma tyrosine have been found in ME/CFS patients.[1][2]
References[edit | edit source]
- ↑ Georgiades, Evelina; Behan, Wilhelmina M. H.; Kilduff, Liam P.; Hadjicharalambous, Marios; Mackie, Eileen E.; Wilson, John; Ward, Susan A.; Pitsiladis, Yannis P. (August 2003). "Chronic fatigue syndrome: new evidence for a central fatigue disorder". Clinical Science (London, England: 1979). 105 (2): 213–218. doi:10.1042/CS20020354. ISSN 0143-5221. PMID 12708966.
- ↑ Jones, Mark G.; Cooper, Elizabeth; Amjad, Saira; Goodwin, C. Stewart; Barron, Jeffrey L.; Chalmers, Ronald A. (November 1, 2005). "Urinary and plasma organic acids and amino acids in chronic fatigue syndrome". Clinica Chimica Acta. 361 (1): 150–158. doi:10.1016/j.cccn.2005.05.023. ISSN 0009-8981.
