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Tethered cord syndrome
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=== Blood flow === People with tethered cord syndrome have reduced blood flow to the spinal cord.<ref name=":2" /> โTraction on the caudal cord results in decreased blood flow causing metabolic derangements that culminate in motor, sensory, and urinary neurological deficits. The untethering operation restores blood flow and reverses the clinical picture in most symptomatic cases.โ<ref>{{Cite journal | last =Rekate | first = Harold L. | last2 = Theodore | first2 = Nicholas | last3 = Kalani | first3 = M. Yashar | last4 = Filippidis | first4 = Aristotelis S. | date = 2010-07-01 | title = Spinal cord traction, vascular compromise, hypoxia, and metabolic derangements in the pathophysiology of tethered cord syndrome|url=https://thejns.org/view/journals/neurosurg-focus/29/1/2010.3.focus1085.xml|journal=Neurosurgical Focus|language=en-US|volume=29|issue=1| pages = E9|doi=10.3171/2010.3.FOCUS1085|issn=1092-0684}}</ref> In a study of five children undergoing surgery for tethered cord syndrome group, spinal cord blood flow prior to untethering was a mean of 12.6 ml/min per 100 g of tissue. It increased in all cases after release to a mean of 29.4 ml/min per 100 g of tissue.<ref>{{Cite journal | last =Danto | first = Joseph | last2 = Greenberg | first2 = Burt M. | last3 = Rosenthal | first3 = Alan D. | last4 = Schneider | first4 = Steven J. | date = 1993-02-01 | title = A Preliminary Report on the Use of Laser-Doppler Flowmetry during Tethered Spinal Cord Release|url=https://academic.oup.com/neurosurgery/article/32/2/214/2804055|journal=Neurosurgery|language=en|volume=32|issue=2|pages=214โ218|doi=10.1227/00006123-199302000-00010|issn=0148-396X}}</ref>
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