Talk:Differential diagnosis

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== Would a table organized by category of illness be more readable / more usable? ~Njt (talk) 00:08, January 10, 2022 (UTC) ==

Differential diagnosis[edit source | reply | new]

[1]

Common comorbidities[edit source | reply | new]

[2] Possibly add in a table or add to column below?

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Category Potential comorbidities
Autonomic dysfunction postural orthostatic tachycardia syndrome (POTS), neurally mediated hypotension (NMH), orthostatic hypotension
Rheumatological disorders Fibromyalgia, Ehlers-Danlos syndrome, temporomandibular joint disorder, Sicca syndrome (dry eyes/mouth)
Neurological disorders sensory hypersensitivities - light sensitivity, hyperacusis, touch sensitivity, odor sensitivities or chemical sensitivities), poor balance, migraine, headache, peripheral neuropathy, small fiber neuropathy
Immunological disorders new allergies and intolerances or worsened allergies, mast cell activation syndrome, multiple chemical sensitivity, chronic infections and immunodeficiencies
Gastrointestinal disorders food allergy, food intolerance, milk protein allergy / intolerance, gut motility issues, celiac disease, irritable bowel syndrome, small intestinal bacterial overgrowth
Endocrine/metabolic disorders hypothyroidism, hypothalamus-pituitary-adrenal axis dysregulation (capitals? or hypothalamic-pituitary-adrenal axis dysregulation?) (low normal or flattened cortisol curve), metabolic syndrome
Sleep disorders sleep apnea, restless leg syndrome, periodic limb movement disorder
Psychiatric disorders secondary anxiety, secondary depression
Gynecological disorders endometriosis, Premenstrual syndrome (PMS), vulvodynia
MISC interstitial cystitis, overactive bladder, nutritional deficiencies (malnutrition), Vitamin B12 deficiency, Vitamin D deficiency, obesity

Info moved here from page[edit source | reply | new]

Unable to find references for these statements:

There are however some diseases, which can mimic ME/CFS. Some presentations of these illnesses could meet even the most strict ME/CFS diagnostic criteria (CCC and ICC), resulting in patients being wrongly diagnosed with ME/CFS, whilst suffering from something else. These will be discussed in detail below.[citation needed]

No References but surely other diagnoses are more commonly misdiagnosed then structural issues? ~Njt (talk) 22:23, April 20, 2022 (UTC)

Chiari Malformation[edit source | reply | new]

Chiari malformation, is a structural deformity, where a part of the brain stem is out of its normal position. This disease can present with many neurologic symptoms that very similar to ME/CFS and should be excluded. Usually this is done via MRI scan. There was one report however of a missed Chiari problem, that was only visible in a MRI scan in the standing position.

Craniocervical Instability[edit source | reply | new]

Craniocervical instability is another structural problem, where the tendons that connect the base of the skull with the spinal cord are loose, causing brain stem compression, which in turn causes many neurologic symptoms similar to ME/CFS. Several anecdotal reports of complete recovery following CCI surgery have been posted on ME/CFS support forums. However it is yet to be determined how common this issue is with ME/CFS patients.

  1. U.S. ME/CFS Clinician Coalition (July 2020). "Diagnosing and Treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)" (PDF) (2 ed.). p. 3.
  2. U.S. ME/CFS Clinician Coalition (July 2020). "Diagnosing and Treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)" (PDF) (2 ed.). p. 4.