Savella

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Revision as of 16:41, January 17, 2022 by Notjusttired (talk | contribs) (outline)

Savella or milnacipran (generic name) is an antidepressant that is also licensed for use in fibromyalgia. No studies have been carried out on the effectiveness of Savella in ME/CFS patients, although off-label use of psychiatric medications in ME/CFS has generally been ineffective.[1]

Theory[edit | edit source]

Evidence[edit | edit source]

Savella is an FDA-approved drug for fibromyalgia, with improvements in pain, sleep and more limited improvements in fatigue.

No clinical trials have been done for Savella/milnacipran in ME/CFS.

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Costs and availability[edit | edit source]

Perscription only drug.

Notable studies[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. Kim, Do-Young; Lee, Jin-Seok; Park, Samuel-Young; Kim, Soo-Jin; Son, Chang-Gue (January 6, 2020). "Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)". Journal of Translational Medicine. 18 (1): 1–12. doi:10.1186/s12967-019-02196-9. ISSN 1479-5876. PMC 6943902. PMID 31906979.