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Rotigotine
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'''Rotigotine''' is a dopamine agonist used for [[Parkinson's disease]] and [[restless leg syndrome]] (RLS) which is available only as a slow-release transdermal patch applied to the skin.<ref name="drugscom">{{Cite web|url=https://www.drugs.com/cdi/rotigotine.html| title = Rotigotine: Indications, Side Effects, Warnings|website=Drugs.com|language=en|access-date=2022-02-21}}</ref><ref name="transdermal">{{Cite web|url=https://www.drugs.com/cons/rotigotine-transdermal.html| title = Rotigotine Transdermal Advanced Patient Information|website=Drugs.com|language=en|access-date=2022-02-21}}</ref> Rotigotine is also sold under the brand name ''Neupro''.<ref name="drugscom" /><ref>{{Cite web|url=https://medlineplus.gov/druginfo/meds/a697029.html| title = Pramipexole: MedlinePlus Drug Information|website=medlineplus.gov|language=en|access-date=2022-02-21}}</ref> Rotigotine is in the same class of drugs as [[ropinirole]] and [[pramipexole]].<ref name="Okifuji2016"/> ==Theory== ==Evidence== No clinicial trials have yet been carried out of rotigotine for patients with ME/CFS. A single study of rotigotine for [[fibromyalgia]] had high dropout rates for both the drug and placebo, but did not appear to show a significant improvement in [[pain]] or other fibromyalgia symptoms at doses of 4mg or 8mg.<ref name="Okifuji2016">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066139/</ref><ref name="NCT00464737">https://clinicaltrials.gov/ct2/show/results/NCT00464737</ref> There is inconsistent evidence of the effect of rotigotine on [[fatigue]] in Parkinson's disease.<ref name="PSG2003">https://jamanetwork.com/journals/jamaneurology/article-abstract/785048</ref><ref name="Hauser2012">https://n.neurology.org/content/78/1_Supplement/P06.088.short</ref> ==Clinicians== *[[Olli Polo]] ==Risks and safety== ==Costs and availability== ==Notable studies == *2007, The use of rotigotine for treatment of reducing signs and symptoms of fibromyalgia in adults. [https://clinicaltrials.gov/ct2/show/NCT00464737 Summary (not peer reviewed)] ==See also== *[[Restless leg syndrome]] *[[Pramipexole]] ==Learn more== *[https://www.drugs.com/cdi/rotigotine.html Rotigotine] - drugs.com *[https://www.drugs.com/cons/rotigotine-transdermal.html Rotigotine transdermal] - drugs.com *[https://medlineplus.gov/druginfo/meds/a607059.html Rotigotine] - MedlinePlus *[https://go.drugbank.com/drugs/DB05271 Rotigotine] - DrugBank Online ==References== {{reflist}} [[Category:Potential treatments]] [[Category:Dopamine agonists]]
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