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Ronald Glaser
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[[File:Ronald Glaser.png|200px|thumb|right|Source:medicine.osu.edu]] '''M. Ronald Glaser''', Ph.D, (d. April 3, 2019)<ref>{{Cite web|url=https://www.schoedinger.com/obituaries/Ronald-Glaser/| title = Ronald Glaser - View Obituary & Service Information|website=Ronald Glaser Obituary|language=en|access-date=2019-04-06}}</ref> was a professor in the Department of Cancer Biology and Genetics and Director of the Institute for Behavioral Medicine Research at the College of Medicine, The Ohio State University, Columbus, Ohio. His main research interests were tumor virology/stress and immunology.<ref>https://medicine.osu.edu/cancer-biology-genetics/directory/molecular-virology/glaser-m-ronald-phd/Pages/index.aspx</ref> Dr. Glaser advocated that a possible subset of [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] (ME/CFS) could be from viral reactivation following a stressful event.<ref>http://www.ei-resource.org/columns/phoenix-rising/chronic-fatigue-syndrome-and-the-pathophysiology-of-epstein-barr-virus-ebv-infection</ref> In 2012, Dr Glaser and his team announced work on a possible [[diagnostic biomarker]] for [[Chronic fatigue syndrome|CFS]] that involves the detection of EBV-encoded DNA polymerase and EBV-encoded dUTPase, two proteins that are produced early in the process of [[Epstein-Barr virus]] reactivation.<ref>http://researchnews.osu.edu/archive/chronfatigue.htm</ref> ==Chronic Fatigue Syndrome Advisory Committee== Dr. Glaser served as a voting member of the [[Chronic Fatigue Syndrome Advisory Committee]] from 04/01/07 to 04/01/11.<ref name="Spring, 2009" /><ref name="Fall, 2010" /> ==2001 CDC Case Definition Workshop== In 2001, the CDC held a three-day workshop on ''Issues Related to the Chronic Fatigue Syndrome (CFS) Research Case Definition.'' Dr Glaser was one of the invited participants. During the workshop, Dr Glaser gave the presentation: "Immune Modulation by Latent Herpesvirus Proteins."<ref>https://www.cdc.gov/cfs/meetings/case_def_05_2001.html</ref> ==Notable studies== *1986, Stress depresses interferon production by [[leukocyte]]s concomitant with a decrease in [[natural killer cell]] activity.<ref name="GlaserR1986" /> *1998, Stress-associated immune modulation: relevance to viral infections and [[chronic fatigue syndrome]].<ref name="Glaser, 1998" /> *2005, Stress-associated changes in the steady state expression of latent [[Epstein-Barr virus|Epstein-Barr Virus]]: Implications for [[Chronic Fatigue Syndrome]] and Cancer<ref name="Glaser, 2005" /> *2012, Antibody to [[Epstein-Barr virus|Epstein-Barr Virus]] Deoxyuridine Triphosphate Nucleotidohydrolase and Deoxyribonucleotide Polymerase in a [[Chronic Fatigue Syndrome]] Subset<ref name="Lerner, 2012" /> [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047891 (Full Text)] ==Talks and interviews== ==Online presence== *[https://medicine.osu.edu/cancer-biology-genetics/directory/molecular-virology/glaser-m-ronald-phd/Pages/index.aspx Ohio State University Faculty page] *[https://www.ncbi.nlm.nih.gov/pubmed?term=glaser,%20ronald PubMed] ==Learn more== *2013, [http://www.ei-resource.org/columns/phoenix-rising/chronic-fatigue-syndrome-and-the-pathophysiology-of-epstein-barr-virus-ebv-infection/ "Dr. Ronald Glaser - Chronic Fatigue Syndrome and the Pathophysiology of EBV Infection " by] [[Cort Johnson]] *2019, [https://www.schoedinger.com/obituaries/Ronald-Glaser/#!/Obituary Obituary] ==See also== *[[Chronic Fatigue Syndrome Advisory Committee]] *[[Diagnostic biomarker]] ==References== <references> <ref name="Spring, 2009">{{citation | author = HHS.gov | title = May 27 & 28, 2009 CFSAC Meeting | type = Roster | date = 2009 | url = http://wayback.archive-it.org/3919/20140324192913/http://www.hhs.gov/advcomcfs/meetings/minutes/cfsac052709min.pdf }}</ref> <ref name="Fall, 2010">{{citation | author = HHS.gov | title = October 12 & 13, 2010 CFSAC Meeting | type = Roster | date = 2010 | url = http://wayback.archive-it.org/3919/20140324192901/http://www.hhs.gov/advcomcfs/meetings/minutes/viewattachment.pdf }}</ref> <ref name="GlaserR1986">{{citation | last1 = Glaser | first1 = Ronald | authorlink1 = Ronald Glaser | last2 = Rice | first2 = John | authorlink2 = | last3 = Speicher | first3 = Carl E. | authorlink3 = | last4 = Stout | first4 = Julie C. | authorlink4 = | last5 = Kiecolt-Glaser | first5 = Janice K. | authorlink5 = | title = Stress depresses interferon production by leukocytes concomitant with a decrease in natural killer cell activity. | journal = Behavioral Neuroscience | volume = 100 | issue =5 | date = Oct 1986 | page = 675-678 | doi = 10.1037/0735-7044.100.5.675 | url = http://psycnet.apa.org/psycinfo/1987-06499-001 }}</ref> <ref name="Glaser, 1998">{{Citation | last1 = Glaser | first1 = R | authorlink1 = Ronald Glaser | last2 = Kiecolt-Glaser | first2 = JK | authorlink2 = | title = Stress-associated immune modulation: relevance to viral infections and chronic fatigue syndrome. | journal = The American Journal of Medicine | volume = 105 | issue =3A | page = 35S-42S | date = 1998 | pmid = 9790480 | doi = }}</ref> <ref name="Glaser, 2005">{{Citation | last1 = Glaser | first1 = R. | authorlink1 = Ronald Glaser | last2 = Padgett | first2 = D.A. | authorlink2 = | last3 = Litsky | first3 = M.L. | authorlink3 = | last4 = Baiocchi | first4 = R.A. | authorlink4 = | last5 = Yang | first5 = E.V. | authorlink5 = | last6 = Chen | first6 = M. | authorlink6 = | last7 = Yeh | first7 = P-E. | authorlink7 = | last8 = Klimas | first8 = N.G. | authorlink8 = Nancy Klimas | last9 = Marshall | first9 = G.D. | authorlink9 = Gailen Marshall | last10 = Whiteside | first10 = T. | author-link10 = | last11 = Herberman | first11 = R. | authorlink11 = | last12 =Kiecolt-Glaser | first12 = J.K. | authorlink12 = | last13 = Williams | first13 = M.V. | authorlink13 = | title = Stress-associated changes in the steady state expression of latent Epstein-Barr Virus: Implications for Chronic Fatigue Syndrome and Cancer | journal = Brain, Behavior and Immunity | volume = 19 | issue = 2 | page = 91-103 | date = 2005 | pmid = 15664781 | doi = 10.1016/j.bbi.2004.09.001 }}</ref> <ref name="Lerner, 2012">{{Citation | last1 = Lerner | first1 = AM | authorlink1 = A Martin Lerner | last2 = Ariza | first2 = ME | authorlink2 = | last3 = Williams | first3 = M | authorlink3 = | last4 = Jason | first4 = L | authorlink4 = Leonard Jason | last5 = Beqaj | first5 = S | authorlink5 = | last6 = Fitzgerald | first6 = JT | authorlink6 = | last7 = Lemeshow | first7 = S | authorlink7 = | last8 = Glaser | first8 = R | authorlink8 = Ronald Glaser | title = Antibody to Epstein-Barr Virus Deoxyuridine Triphosphate Nucleotidohydrolase and Deoxyribonucleotide Polymerase in a Chronic Fatigue Syndrome Subset | journal = PLoS ONE | volume = 7 | issue = 11 | page = e47891 | date = 2012 | pmid = | doi = 10.1371/journal.pone.0047891 }}</ref> </references> [[Category:Researchers]] [[Category:US researchers]] [[Category:CFSAC members]]
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