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Research bias in ME/CFS
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==Clinicians' disbelief in unsuccessful trials== Some clinicians appear to have become so convinced that a treatment ''must work'' during a trial that a null or negative response to the treatment has been misattributed to a patient mistake. Examples include the [[FINE trial]], which was the sister trial to the PACE trial but for severely ill patients, where a null result was published along with a comment that some nurses delivering the treatment felt that "the bastards [patients] just don't want to get better".{{citation needed| date = Sep 2020}} Clear conflicts of interest with representing both insurance companies in dismissing claims for illness insurance, in private training companies run by clinician researchers, and in prior published popular self-help books for chronic fatigue or CFS commonly occur, and are often not disclosed in publication, including in all of the three PACE trial principle authors, at least one other PACE trial author and the majority of [[Biopsychosocial model|biopsychosocial treatment]] studies. A publication by [[Simon Wessely]], one of the clinicians who delivered treatment in the PACE trial, described the management of the trial using a comparison of steering a ship to its pre-determined destination.{{citation needed| date = Sep 2020}}
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