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A '''relapse''' in [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] is .<ref name="ng206" /><ref name="ICC2011primer" /> ==NHS definition== {{Quote box|quote=A sustained and marked exacerbation of symptoms lasting longer than a [[flare-up]] and needing a substantial and sustained adjustment to the person's [[energy management]]. It may not be clear in the early stages of a symptom exacerbation whether it is a flare‑up or a relapse. Relapses can lead to a long-term reduction in the person's energy limits.<ref name="ng206" /> | author=ME/CFS:diagnosis and management. NICE guideline (2021). | title=Relapse}} The UK's [[National Health Service]] definition of a relapse can be found within the 2021 [[NICE guidelines]].<ref name="ng206">{{Cite web|url=https://www.nice.org.uk/guidance/ng206/chapter/recommendations#terms-used-in-this-guideline | title = Myalgic Encephalomyelitis (or Encephalopathy)/Chronic Fatigue Syndrome:diagnosis and management. NICE guideline. | last=NICE Guideline Development Group | first = | authorlink = |publisher=[[National Institute for Health and Care Excellence]] | date = 2021-10-29}}</ref> ==International Consensus Criteria == The [[International Consensus Criteria]] does not define what a relapse is, but states that relapses can last for days, weeks or longer.<ref name="ICC2011primer">{{citation | last1 = Carruthers | first1 = BM | authorlink1 = Bruce Carruthers | last2 = van de Sande | first2 = MI | authorlink2 = Marjorie van de Sande | last3 = De Meirleir | first3 = KL | authorlink3 = Kenny de Meirleir | last4 = Klimas | first4 = NG | authorlink4 = Nancy Klimas | last5 = Broderick | first5 = G | authorlink5 = Gordon Broderick | last6 = Mitchell | first6 = T | authorlink6 = Terry Mitchell | last7 = Staines | first7 = D | authorlink7 = Donald Staines | last8 = Powles | first8 = ACP | authorlink8 = A C Peter Powles | last9 = Speight | first9 = N | authorlink9 = Nigel Speight | last10 = Vallings | first10 = R | authorlink10 = Rosamund Vallings | last11 = Bateman | first11 = L | authorlink11 = Lucinda Bateman | last12 = Bell | first12 = DS | authorlink12 = David Bell | last13 = Carlo-Stella | first13 = N | authorlink13 = Nicoletta Carlo-Stella | last14 = Chia | first14 = J | authorlink14 = John Chia | last15 = Darragh | first15 = A | authorlink15 = Austin Darragh | last16 = Gerken | first16 = A | authorlink16 = Anne Gerken | last17 = Jo | first17 = D | authorlink17 = Daehyun Jo | last18 = Lewis | first18 = DP | authorlink18 = Donald Lewis | last19 = Light | first19 = AR | authorlink19 = Alan Light | last20 = Light | first20 = KC | authorlink20 = Kathleen Light | last21 = Marshall-Gradisnik | first21 = S | authorlink21 = Sonya Marshall-Gradisnik | last22 = McLaren-Howard | first22 = J | authorlink22 = John McLaren-Howard | last23 = Mena | first23 = I | authorlink23 = Ismael Mena | last24 = Miwa | first24 = K | authorlink24 = Kunihisa Miwa | last25 = Murovska | first25 = M | authorlink25= Modra Murovska | last26 = Stevens | first26 = SR | authorlink26 = Staci Stevens | title = Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners | date = 2012| isbn = 978-0-9739335-3-6 | url = http://www.investinme.org/Documents/Guidelines/Myalgic%20Encephalomyelitis%20International%20Consensus%20Primer%20-2012-11-26.pdf}}</ref> ==Impact == The impact of a relapse varies from person to person. But most will find that they will have to revisit any coping mechanisms they have used prior to relapse to manage symptoms or avoid triggers. Energy levels will be heavily depleted and it is likely to take several weeks if not months or longer to return to pre-relapse levels.{{citation needed| date = Mar 2023}} Similarly, with symptoms it will take a long time for them to ease, and this in turn goes to aggravate energy levels.{{citation needed| date = Mar 2023|note=How many don't return to previous level after relapse?}} ==Notable studies == ==See also == *[[Post-exertional malaise]] *[[Myalgic encephalomyelitis]] *[[Chronic fatigue syndrome]] *[[Flare-up]] *[[Sensory overload]] *[[Disability]] ==Learn more== ==References == {{Reflist}} [[Category:ME/CFS terminology]]
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