Regulatory T cell

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Regulatory T cells (Tregs) are anti-inflammatory. They produce the anti-inflammatory cytokines TGF-β and IL-10. They suppress effector Th1, Th2, and Th17.

Dietary and environmental factors[edit | edit source]

Vitamin D improves regulatory T cell function in healthy adults[1] and in patients with relapsing remitting multiple sclerosis,[2] suggesting that it may play a role in both preventing and ameliorating autoimmune disease.

Various species of probiotics have been shown to increased FoxP3 expression in animal models.[3]

Chronic Fatigue Syndrome[edit | edit source]

Tregs are elevated in CFS.[4]

Notable Studies[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Vitamin D increases http://www.ncbi.nlm.nih.gov/pubmed/22069289
  2. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006635
  3. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276397/
  4. http://www.ncbi.nlm.nih.gov/pubmed/24343819
  5. Ramos, S; Brenu, E; Broadley, S; Kwiatek, R; Ng, J; Nguyen, T; Freeman, S; Staines, D; Marshall-Gradisnik, S (March 20, 2016), "Regulatory T, natural killer T and γδ T cells in multiple sclerosis and chronic fatigue syndrome/myalgic encephalomyelitis: a comparison", Asian Pac J Allergy Immunol, doi:10.12932/AP0733