Regulatory T cell
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Regulatory T cells (Tregs) are anti-inflammatory. They produce the anti-inflammatory cytokines TGF-β and IL-10. They suppress effector Th1, Th2, and Th17.
Dietary and environmental factors[edit | edit source]
Vitamin D improves regulatory T cell function in healthy adults[1] and in patients with relapsing remitting multiple sclerosis,[2] suggesting that it may play a role in both preventing and ameliorating autoimmune disease.
Various species of probiotics have been shown to increased FoxP3 expression in animal models.[3]
Chronic Fatigue Syndrome[edit | edit source]
Tregs are elevated in CFS.[4]
Notable Studies[edit | edit source]
- 2016, Regulatory T, natural killer T and γδ T cells in multiple sclerosis and chronic fatigue syndrome/myalgic encephalomyelitis: a comparison.[5]
See also[edit | edit source]
References[edit | edit source]
- ↑ Vitamin D increases http://www.ncbi.nlm.nih.gov/pubmed/22069289
- ↑ http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006635
- ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276397/
- ↑ http://www.ncbi.nlm.nih.gov/pubmed/24343819
- ↑ Ramos, S; Brenu, E; Broadley, S; Kwiatek, R; Ng, J; Nguyen, T; Freeman, S; Staines, D; Marshall-Gradisnik, S (March 20, 2016), "Regulatory T, natural killer T and γδ T cells in multiple sclerosis and chronic fatigue syndrome/myalgic encephalomyelitis: a comparison", Asian Pac J Allergy Immunol, doi:10.12932/AP0733