Prostaglandin

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Prostaglandins are a subclass of eicosanoids derived from long chain fatty acids.

Prostaglandins are involved in a diverse range of functions including vasodilation, uterus contraction, pain, gastric acid secretion, and autonomic neurotransmitters.

Prostaglandins can also by pyrogenic.

Synthesis[edit | edit source]

They are found in almost all cells with a nucleus. They are produced by the oxidation of arachidonic acid, DGLA or EPA from the cell membrane by phospholipase A2.

Exercise[edit | edit source]

In healthy people, Prostaglandin E2 levels are raised significantly for days after exercise.[1]


References[edit | edit source]