Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Progesterone
(section)
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
====Progesterone Resistance & Inflammation in Endometriosis ==== [[Endometriosis]] is a condition in which tissue grows not only on the internal walls of the uterus, but also on the ovaries, fallopian tubes, and external uterine walls, resulting in pain and sometimes infertility. Research suggests that the etiology of endometriosis centers around a disruption of estrogen-progesterone homeostasis in the uterus, caused by "progesterone resistance," which leads to increased inflammation.<ref name="H2014" /> This progesterone resistance may lead to increased production of estrogen and pro-inflammatory [[cytokine]] presence including IL-1Ξ², TNF-Ξ±, LIF, IL-6, IL-8, IL-11, NF-kB, p53, and STAT3. While these [[cytokines]] aid in embryonic implantation, levels that are too high or last too long can lead to aberrant outcomes like endometriosis. Through studying the effects of progesterone on endometriosis and other conditions related to estrogen-dominance, many researchers are optimistic about the development of future treatments.<ref name="H2014" />
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
This page is a member of 5 hidden categories:
Category:All articles needing cleanup from 2019
Category:All articles with unsourced statements
Category:Articles needing cleanup from 2019
Category:Articles with unsourced statements from 2021
Category:Cleanup tagged articles with a reason field from 2019
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs