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Polymyalgia rheumatica
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'''Polymyalgia rheumatica''', or PMR, involves widespread aching and stiffness. == Symptoms and onset == Polymyalgia rheumatica (PMR) involves widespread aching and stiffness, especially the upper arms, neck, lower back and thighs.<ref name=":0" /> This is typically worse in the morning or after inactivity.<ref name=":0" /> Joint pain can be involved, as well as [[disturbed sleep]],<ref name=":0" /> fatigue, mild fever, general feeling of unwellness (malaise), depression, and loss of appetite and unintended weight loss.<ref name=":1">{{Cite web|url=https://www.mayoclinic.org/diseases-conditions/polymyalgia-rheumatica/symptoms-causes/syc-20376539| title = Polymyalgia rheumatica|website=Mayo Clinic| date = June 23, 2018|access-date=2019-07-05}}</ref> Typically PMR affects adults over 50, with age 70 as average onset.<ref name=":0" /> Women are two to three times more likely to develop PMR.<ref name=":1" /> == Diagnosis == PMR often (but necessarily) presents with elevated inflammation levels in blood tests, particularly [[erythrocyte sedimentation rate]] ("sed rate") and [[C-reactive protein]] (CRP).<ref name=":0" /> This is one way to differentiate PMR from [[fibromyalgia]]; however in some PMR patients, these tests may have normal or only slightly elevated results.<ref name=":0" /> PMR is diagnosed with a trial of low-dose [[Corticosteroid|corticosteroids]], with the expectation that if the condition is present, symptoms will respond within two to three weeks and sometimes much sooner (even following the first dose).<ref name=":0" /> == Treatment == Treatment involves tapering to the lowest comfortable dose of corticosteroids and some patients are able to discontinue within a year although others continued for two to three years and symptoms can recur.<ref name=":0" /> Typically PMR affects adults over 50 with age 70 as average onset.<ref name=":0">{{Cite web|url=https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Polymyalgia-Rheumatica | title = Polymyalgia rheumatica | last = Sufka | first=Paul | authorlink = Paul Sufka|website=American College of Rheumatology | date = March 2019|access-date=2019-07-05}}</ref> == Studies == [[Category:Diagnoses]] * 1988, "Chronic Epstein-Barr virus infection" syndrome and polymyalgia rheumatica.<ref>{{Cite journal | last = Buchwald | first=D | authorlink = | last2 = Sullivan | first2 = JL | authorlink2 = | last3 = Leddy | first3 = S | authorlink3 = | last4 = Komaroff | authorlink4 = Anthony Komaroff | authorlink5 = | date = March 1988| title = "Chronic Epstein-Barr virus infection" syndrome and polymyalgia rheumatica.|url=https://www.ncbi.nlm.nih.gov/pubmed/2837573|journal=Journal of Rheumatology|volume=15|issue=3 | pages = 479-82|quote=|via=PubMed | authorlink6 = | first4 = AL}}</ref> ([[pubmed:2837573|Abstract]]) == References == {{Reflist}} {{stub}}
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