Oxford criteria: Difference between revisions

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==Criticisms==
==Criticisms==
*[[How have selection bias and disease misclassification undermined the validity of myalgic encephalomyelitis/chronic fatigue syndrome studies?]]
*[[How have selection bias and disease misclassification undermined the validity of myalgic encephalomyelitis/chronic fatigue syndrome studies?]] For every 15 patients selected under Oxford criteria, 14 will be false positives when compared to [[Canadian Consensus Criteria]]. The [[Pace trial]] and [[FINE trial]] used Oxford criteria.
*[[Post-exertional malaise]] is not a listed symptom. When this symptom is not mandatory, patients with [[Chronic Fatigue]] and not the grossly misnamed disease [[Chronic Fatigue Syndrome]] are swept into the study.<ref>[https://voat.co/v/CFS/comments/254402 Chronic Fatigue is NOT Chronic Fatigue Syndrome - VOAT]</ref>
*[[Post-exertional malaise]] is not a listed symptom. When this symptom is not mandatory, patients with [[Chronic Fatigue]] and not the grossly misnamed disease [[Chronic Fatigue Syndrome]] are swept into the study.<ref>[https://voat.co/v/CFS/comments/254402 Chronic Fatigue is NOT Chronic Fatigue Syndrome - VOAT]</ref>
*Depression is not an absolute exception for a possible cause of Chronic Fatigue (not to be confused with Chronic Fatigue Syndrome.) This allows for patients with depression to be misdiagnosed with [[CFS]].<ref>[http://arthritis.about.com/od/fatigue/f/chronicfatigue.htm Chronic Fatigue Versus Chronic Fatigue Syndrome - About.com HEALTH By: Carol Eustice]</ref>
*Depression is not an absolute exception for a possible cause of Chronic Fatigue (not to be confused with Chronic Fatigue Syndrome.) This allows for patients with depression to be misdiagnosed with [[CFS]].<ref>[http://arthritis.about.com/od/fatigue/f/chronicfatigue.htm Chronic Fatigue Versus Chronic Fatigue Syndrome - About.com HEALTH By: Carol Eustice]</ref>
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*'''US NIH Report Calls for UK Definition of ME/CFS to be Scrapped''' - ''The Argus Report'' By: Penny Swift.
*'''US NIH Report Calls for UK Definition of ME/CFS to be Scrapped''' - ''The Argus Report'' By: Penny Swift.
::"The [https://en.wikipedia.org/wiki/National_Institutes_of_Health United States National Institutes of Health] (NIH) has issued a draft report that highlights the dire need for scientific research that will help find a cure for the millions of people suffering from myalgic encephalomyelitis/chronic fatigue syndrome ([[ME/CFS]]) worldwide. The report also highlights the fact that the decades-old UK Royal Society of Medicine’s '''Oxford criteria''' for ME/CFS are severely “flawed,” and that continuing to use these criteria may “cause harm.” Further, the NIH report says that the Royal Society definition should “be retired” and replaced with a single case definition agreed to by the ME/CFS community."<ref>[http://theargusreport.com/us-nih-report-calls-uk-definition-mecfs-scrapped/ US NIH Report Calls for UK Definition of ME/CFS to be Scrapped - The Argus Report By: Penny Swift]</ref>
 
:''Excerpt''
::The [https://en.wikipedia.org/wiki/National_Institutes_of_Health United States National Institutes of Health] (NIH) has issued a draft report that highlights the dire need for scientific research that will help find a cure for the millions of people suffering from myalgic encephalomyelitis/chronic fatigue syndrome ([[ME/CFS]]) worldwide. The report also highlights the fact that the decades-old UK Royal Society of Medicine’s '''Oxford criteria''' for ME/CFS are severely “flawed,” and that continuing to use these criteria may “cause harm.” Further, the NIH report says that the Royal Society definition should “be retired” and replaced with a single case definition agreed to by the ME/CFS community.<ref>[http://theargusreport.com/us-nih-report-calls-uk-definition-mecfs-scrapped/ US NIH Report Calls for UK Definition of ME/CFS to be Scrapped - The Argus Report By: Penny Swift]</ref>


==Learn more==
==Learn more==
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==See also==
==See also==
*[[FINE trial]]
*[[PACE trial]]
*[[PACE trial]]


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<references>
<references>
<ref name="Njoku, 2016">{{citation
<ref name="Njoku, 2016">{{citation
| author  = Mary Gloria C. Njoku
| author  = [[Mary Gloria Njoku| Mary Gloria C. Njoku]]
| title  = Myalgic, Encephalomyelitis/Chronic Fatigue Syndrome: History, Diagnostic Criteria and Prevalence
| title  = Myalgic, Encephalomyelitis/Chronic Fatigue Syndrome: History, Diagnostic Criteria and Prevalence
| type    = ebook
| type    = ebook

Revision as of 01:22, June 29, 2017

The Oxford criteria are a set of criteria for the diagnosis Chronic Fatigue Syndrome published in 1991 by a group of psychiatrists. They identify two broad syndromes and are used primarily for research purposes.[1] The Oxford criteria was used for PACE trial participation.[2][3]

Authors[edit | edit source]

Michael Sharpe, Len Archard, Jangu Banatvala, Leszek Borysiewicz, Anthony Clare, Anthony David, Richard Edwards, Keith Hawton, Harold Lambert, Russell Lane

Definition[edit | edit source]

Chronic fatigue syndrome[edit | edit source]

Post-infectious Fatigue Syndrome (PIFS)[edit | edit source]

A sub-type of CFS which either follows an infection or is associated with a current infection (although whether such associated infection is of aetiological significance (i.e. whether it is the cause of the symptoms) is a topic for research).

To meet the research criteria for PIFS patients must:

  • i. fulfil the criteria for CFS as defined above (i.e. the Oxford definition)
  • ii. should also fulfil the following additional criteria:
  • (a) There is definite evidence of infection at onset or presentation (a patient’s self-report is unlikely to be sufficiently reliable).
  • (b) the syndrome is present for a minimum of 6 months after onset of infection.
  • (c) the infection has been corroborated by laboratory evidence.

PDF for Oxford Definition CFS and PIFS[edit | edit source]

PDF: A report - chronic fatigue syndrome: guidelines for research - Journal of the Royal Society of Medicine - Volume 84 February 1991 118-121[4]

Criticisms[edit | edit source]

  • US NIH Report Calls for UK Definition of ME/CFS to be Scrapped - The Argus Report By: Penny Swift.
Excerpt
The United States National Institutes of Health (NIH) has issued a draft report that highlights the dire need for scientific research that will help find a cure for the millions of people suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) worldwide. The report also highlights the fact that the decades-old UK Royal Society of Medicine’s Oxford criteria for ME/CFS are severely “flawed,” and that continuing to use these criteria may “cause harm.” Further, the NIH report says that the Royal Society definition should “be retired” and replaced with a single case definition agreed to by the ME/CFS community.[8]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]