Outcome switching
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Outcome switching is when authors of a clinical trial "move the goal posts" during a trial to achieve the desired results.
The PACE trial authors, in a clinical trial of ME/CFS patients undergoing GET/CBT, employed this tactic.
Articles on Outcome switching in clinical trials[edit | edit source]
- How Outcome Switching is Corrupting Medical Research Psychology Today By: Christopher Lane, Ph.D. - Apr 30, 2916
- For my next trick... Economist - Mar 26, 2016
- Is Outcome Switching Still A Problem In Clinical Trials? Clinical Leader By: Ed Miseta - Mar 7, 2016
- How researchers dupe the public with a sneaky practice called "outcome switching" VOX By: Ben Goldacre Update: Julia Belluz - Dec 29, 2016
Tracking outcome switching
PACE trial[edit | edit source]
- In 2016, Julie Rehmeyer gave the talk Bad Statistics, Bad Reporting, Bad Impact on Patients: The Story of the PACE Trial Slideshow given at the 2016 Joint Statistics Meetings (Notes may be be viewed by clicking the “Notes” icon just above the comments section in the slideshow link.)
- David Tuller spoke about and answered questions on the PACE trial and its flaws.
- Feb 27, 2016, While in Amsterdam at The Forgotten Plague Conference, David Tuller gave an interview with Frank Twisk discussing the flaws of the Pace trial. That interview can be viewed here.[3]
Learn more[edit | edit source]
See also[edit | edit source]
- Alem Matthees won the Freedom of Information Act request for PACE trial data.
References[edit | edit source]
- ↑ The COMPare Trials Project. Ben Goldacre, Henry Drysdale, Anna Powell-Smith, Aaron Dale, Ioan Milosevic, Eirion Slade, Philip Hartley, Cicely Marston, Kamal Mahtani, Carl Heneghan. www.COMPare-trials.org, 2016.
- ↑ https://www.youtube.com/watch?v=1fS6Gzc52VI
- ↑ https://www.youtube.com/watch?v=UN1bYhkDHA4&feature=youtu.be