Nicotinamide adenine dinucleotide
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Nicotinamide adenine dinucleotide or NAD or NADH is a coenzyme found in all living cells. Nicotinamide adenine dinucleotide exists in two forms, an oxidized and reduced form abbreviated as NAD+ and NADH respectively.
Evidence
A systematic review of alternative treatments found evidence of the effectiveness of oral NADH in patients with ME/CFS.[1]
Notable studies
- 2016, Pharmacological NAD-Boosting Strategies Improve Mitochondrial Homeostasis in Human Complex I-Mutant Fibroblasts
- 2010, Alternative medical interventions used in the treatment and management of myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia[1]
- 2004, Comparison of oral nicotinamide adenine dinucleotide (NADH) versus conventional therapy for chronic fatigue syndrome[2] - (Full text)
- 1999, Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome[3] - (Full text)
Blogs and articles
Learn more
See also
- Mitochondrion
- Sirtuin 1 (SIRT1)
References
- ↑ 1.0 1.1 Porter, Nicole S.; Jason, Leonard A.; Boulton, Aaron; Bothne, Nancy; Coleman, Blair (March 2010). "Alternative medical interventions used in the treatment and management of myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia" (PDF). Journal of Alternative and Complementary Medicine (New York, N.Y.). 16 (3): 235–249. doi:10.1089/acm.2008.0376. ISSN 1557-7708. PMID 20192908.
- ↑ Santaella, ML; Font, I; Disdier, OM (June 2004). "Comparison of oral nicotinamide adenine dinucleotide (NADH) versus conventional therapy for chronic fatigue syndrome". Puerto Rico health sciences journal. pp. 89–93. PMID 15377055.
- ↑ Forsyth, Linda M; Preuss, Harry G; MacDowell, Ana L; Chiazze, Leonard; Birkmayer, George D; Bellanti, Joseph A (February 1, 1999). "Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome". Annals of Allergy, Asthma & Immunology. 82 (2): 185–191. doi:10.1016/S1081-1206(10)62595-1. ISSN 1081-1206.
