Nancy Klimas: Difference between revisions
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==International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis== | ==International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis== | ||
Dr. Klimas served as past President of the Board of Directors of the [[International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis]] ([[IACFS/ME]]) from 2004-2009.<ref>http://iacfsme.org/Organization/Committees-of-the-IACFS-ME.aspx</ref> She has been awarded the [[IACFS/ME]] Nelson Gantz Outstanding Clinician Award (in 2011) and the [[IACFS/ME]] Rudy Perpich Senior Lectureship Award (in 2014).<ref>http://iacfsme.org/Organization/Former-IACFS-ME-Awardees.aspx</ref> | Dr. Klimas served as past President of the Board of Directors of the [[International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis]] ([[IACFS/ME]]) from 2004-2009.<ref>http://iacfsme.org/Organization/Committees-of-the-IACFS-ME.aspx</ref> She has been awarded the [[IACFS/ME]] Nelson Gantz Outstanding Clinician Award (in 2011) and the [[IACFS/ME]] Rudy Perpich Senior Lectureship Award (in 2014).<ref>http://iacfsme.org/Organization/Former-IACFS-ME-Awardees.aspx</ref> | ||
==ME/CFS Common Data Element (CDE) Project== | |||
Co-chair of the Immune Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the [[National Institute of Neurological Disorders and Stroke]] and the [[Centers for Disease Control & Prevention]].<ref>https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?%2fnindscdereports%2fRoster&rs%3aCommand=Render&rc:Parameters=false&diseaseid=MECFS&custom:disableExcel=true&custom:disableXML=true&custom:disableCSV=true</ref> | |||
==Notable studies== | ==Notable studies== |
Revision as of 14:04, June 23, 2018
Nancy G. Klimas, MD, is an American researcher and physician who is the Director at the Institute for Neuro Immune Medicine at Nova Southeastern University in Miami and Ft. Lauderdale, Florida. She is, also: Director of Clinical Immunology Research, Miami VAMC; Professor of Medicine, Department of Clinical Immunology, College of Osteopathic Medicine, Nova Southeastern University; Chair, Department of Clinical Immunology, College of Osteopathic Medicine, Nova Southeastern University; and Professor Emerita, University of Miami, School of Medicine.[1]
Awards[edit | edit source]
- 2014, Rudy Perpich Senior Lectureship Award, presented to a distinguished CFS/FMS scientist, physician or healthcare worker awarded by IACFS/ME[2]
- 2011, Nelson Gantz Outstanding Clinician Award awarded to a physician who emulates Nelson Gantz's clinical acumen, his passion for medicine, and his empathy for persons with CFS/FM awarded by IACFS/ME[3]
2015 Institute of Medicine report[edit | edit source]
Dr. Klimas was one of the ME/CFS experts on the "Committee on the Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome" that was convened to produce the 2015 Institute of Medicine report.[4]
Case definition authorships[edit | edit source]
Klimas is one of the authors of the 2011 case definition, International Consensus Criteria,[5] the 2006 Pediatric Case Definition for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome[6], as well as, one of the authors of the 2003 Canadian Consensus Criteria for ME/CFS, published as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome:Clinical Working Case Definition,Diagnostic and Treatment Protocols[7]
Chronic Fatigue Syndrome Advisory Committee[edit | edit source]
Dr. Klimas served as a voting member of the Chronic Fatigue Syndrome Advisory Committee for the U.S. Department of Health and Human Services from April 1, 2007 to April 1, 2011.[8]
International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis[edit | edit source]
Dr. Klimas served as past President of the Board of Directors of the International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (IACFS/ME) from 2004-2009.[9] She has been awarded the IACFS/ME Nelson Gantz Outstanding Clinician Award (in 2011) and the IACFS/ME Rudy Perpich Senior Lectureship Award (in 2014).[10]
ME/CFS Common Data Element (CDE) Project[edit | edit source]
Co-chair of the Immune Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control & Prevention.[11]
Notable studies[edit | edit source]
- 2018, KPAX002 as a treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A prospective, randomized trial[12] (Full Text)
- 2017, Depression, evening salivary cortisol and inflammation in chronic fatigue syndrome: A psychoneuroendocrinological structural regression model[13] (Abstract)
- 2017, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Gulf War Illness patients exhibit increased humoral responses to the Herpesviruses-encoded dUTPase: Implications in disease pathophysiology: Herpesviruses in ME/CFS and Gulf War Illness[14] (Abstract)
- 2017, Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome[15] (Full Text)
- 2017, Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study[16] (Abstract)
- 2017, Telephone-administered versus live group cognitive behavioral stress management for adults with CFS[17] (Full Text)
- 2016, Poor sleep quality is associated with greater circulating pro-inflammatory cytokines and severity and frequency of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) symptoms in women][18] (Abstract)
- 2016, Illness progression in chronic fatigue syndrome: a shifting immune baseline[19] (Full Text)
- 2016, Tracking post-infectious fatigue in clinic using routine Lab tests.[20] (Full Text)
- 2016, Gastric Enterovirus Infection: A Possible Causative Etiology of Gastroparesis[21] (Abstract)
Earlier studies[edit | edit source]
Interviews & talks[edit | edit source]
There are many videos on YouTube of Nancy Klimas speaking about her work.[22]
- 13 Sept 2017, Interview with CFS/ME researcher Dr. Nancy Klimas conducted by Zach Elwood
- 2 Jun 2017, Speaker at the 12th Invest in ME International ME Conference on "Genetic Signature Study"[23] - DVD available
- Dec 2, 2016, Episode 84 of ME/CFS Alert - Dr Nancy Klimas on ME/CFS Research, Treatment
- Dec 1, 2016 NBCDFW video interview and transcription
- 2014 ME/CFS Diagnosis and Name with Dr. Nancy Klimas
- 2014 ME/CFS Treatment Options Part 1 with Dr. Nancy Klimas
- 2014 ME/CFS Treatment Options Part 2 with Dr. Nancy Klimas
- ME/CFS and Exercise: VO2 Max Testing with Nancy Klimas M.D. PREVIEW
- 2011 ME/CFS Management A Pathogenesis Based Approach (sponsored by ANZMES)
- From Bedside to Bench and Back Again: Untangling the Mystery of Gulf War Illness and Chronic Fatigue Syndrome
Quotations[edit | edit source]
- "They experience a level of disability equal to that of patients with late-stage AIDS and patients undergoing chemotherapy"[24]
Open Letter to The Lancet[edit | edit source]
Two open letters to the editor of The Lancet urged the editor to commission a fully independent review of the PACE trial, which the journal had published in 2011. In 2016, Dr. Klimas, along with 41 colleagues in the ME/CFS field, signed the second letter.
- 10 February 2016, An open letter to The Lancet, again - Virology blog
Online presence[edit | edit source]
Learn more[edit | edit source]
See also[edit | edit source]
- Dr. Gordon Broderick
- Dr. Mary Ann Fletcher
- Dr. Irma Rey
- Dr. Maria Vera
- Institute for Neuro Immune Medicine
References[edit | edit source]
- ↑ http://www.nova.edu/nim/clinic/dr.-nancy-klimas-bio-page.html
- ↑ http://iacfsme.org/Organization/Former-IACFS-ME-Awardees.aspx
- ↑ http://iacfsme.org/Organization/Former-IACFS-ME-Awardees.aspx
- ↑ http://www.ncbi.nlm.nih.gov/books/NBK284904/
- ↑ Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, A C P; Speight, N; Vallings, R; Bateman, L; Baumgarten-Austrheim, B; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Jo, D; Lewis, D; Light, A; Marshall-Gradisnik, S; Mena, I; Mikovits, JA; Miwa, K; Murovska, M; Pall, ML; Stevens, S (2011), "Myalgic encephalomyelitis: International Consensus Criteria.", Journal of Internal Medicine, 270 (4): 327-38, doi:10.1111/j.1365-2796.2011.02428.x, PMID 21777306
- ↑ Jason, Leonard A; Jordan, Karen; Miike, Teruhisa; Bell, David S; Lapp, Charles; Torres-Harding, Susan; Rowe, Kathy; Gurwitt, Alan; De Meirleir, Kenny; Van Hoof, Elke LS (2006), "A Pediatric Case Definition for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome", Journal of Chronic Fatigue Syndrome, 13 (2–3): 1-44, doi:10.1300/J092v13n02_01
- ↑ http://phoenixrising.me/wp-content/uploads/Canadian-definition.pdf
- ↑ http://nih.granicus.com/DocumentViewer.php?file=nih_e174f9bd-ae0f-4a45-9955-827cb608db2f.pdf
- ↑ http://iacfsme.org/Organization/Committees-of-the-IACFS-ME.aspx
- ↑ http://iacfsme.org/Organization/Former-IACFS-ME-Awardees.aspx
- ↑ https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?%2fnindscdereports%2fRoster&rs%3aCommand=Render&rc:Parameters=false&diseaseid=MECFS&custom:disableExcel=true&custom:disableXML=true&custom:disableCSV=true
- ↑ Montoya, Jose G; Anderson, Jill N; Adolphs, Danya L; Bateman, Lucinda; Klimas, Nancy; Levine, Susan M; Garvert, Donn W; Kaiser, Jon D (2018), "KPAX002 as a treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A prospective, randomized trial" (PDF), International Journal of Clinical and Experimental Medicine, 11 (3): 2890-2900
- ↑ Milrad, Sara F.; Hall, Daniel L.; Jutagir, Devika R.; Lattie, Emily G.; Czaja, Sara J.; Perdomo, Dolores M.; Fletcher, Mary Ann; Klimas, Nancy; Antoni, Michael H. (2017), "Depression, evening salivary cortisol and inflammation in chronic fatigue syndrome: A psychoneuroendocrinological structural regression model", Int J Psychophysiol, 0 (0), doi:10.1016/j.ijpsycho.2017.09.009
- ↑ Halpin, P; Williams, MV; Klimas, NG; Fletcher, MA; Barnes, Zachary; Ariza, ME (2017), "Myalgic encephalomyelitis/chronic fatigue syndrome and gulf war illness patients exhibit increased humoral responses to the herpesviruses-encoded dUTPase: Implications in disease pathophysiology", Journal of Medical Virology, doi:10.1002/jmv.24810, PMID 28303641
- ↑ Nagy-Szakal, Dorottya; Williams, Brent L.; Mishra, Nischay; Che, Xiaoyu; Lee, Bohyun; Bateman, Lucinda; Klimas, Nancy G.; Komaroff, Anthony L.; Levine, Susan; Montoya, Jose G.; Peterson, Daniel L.; Ramanan, Devi; Jain, Komal; Eddy, Meredith L.; Hornig, Mady; Lipkin, W. Ian (2017), "Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome", Microbiome, 5 (44), doi:10.1186/s40168-017-0261-y
- ↑ Unger, Elizabeth R.; Lin, Jin-Mann S.; Tian, Hao; Natelson, Benjamin H; Lange, Gudrun; Vu, Diana; Blate, Michelle; Klimas, Nancy G.; Balbin, Elizabeth G.; Bateman, Lucinda; Allen, Ali; Lapp, Charles W.; Springs, Wendy; Kogelnik, Andreas M.; Phan, Catrina C.; Danver, Joan; Podell, Richard N.; Fitzpatrick, Trisha; Peterson, Daniel L.; Gottschalk, C. Gunnar; Rajeevan, Mangalathu S.; MCAM Study Group (2017), "Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study.", American Journal of Epidemiology, 1–10, doi:10.1093/aje/kwx029
- ↑ Hall, DL; Lattie, EG; Milrad, SF; Czaja, S; Fletcher, MA; Klimas, N; Perdomo, D; Antoni, MH (2017), "Telephone-administered versus live group cognitive behavioral stress management for adults with CFS", J Psychosom Res, 93: 41-47, doi:10.1016/j.jpsychores.2016.12.004
- ↑ Milrad, Sara F.; Hall, Daniel L.; Jutagir, Devika R.; Lattie, Emily G.; Ironson, Gail H.; Wohlgemuth, William; Vera Nunez, Maria; Garcia, Lina; Czaja, Sara J.; Perdomo, Dolores M.; Fletcher, Mary Ann; Klimas, Nancy; Antoni, Michael H. (2016), "Poor sleep quality is associated with greater circulating pro-inflammatory cytokines and severity and frequency of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) symptoms in women", Journal of Neuroimmunology, 0 (0), doi:10.1016/j.jneuroim.2016.12.008
- ↑ Russell, Lindsey; Broderick, Gordon; Taylor, Renee; Fernandes, Henrique; Harvey, Jeanna; Barnes, Zachary; Smylie, AnneLiese; Collado, Fanny; Balbin, Elizabeth; Katz, Ben; Klimas, Nancy; Fletcher, Mary Ann (2016), "Illness progression in chronic fatigue syndrome: a shifting immune baseline", BMC Immunology, doi:10.1186/s12865-016-0142-3
- ↑ Harvey, Jeanna M; Broderick, Gordon; Bowie, Alanna; Barnes, Zachary M; Katz, Ben Z; O'Gorman, Maurice R; Vernon, Suzanne D; Fletcher, Mary Ann; Klimas, Nancy; Taylor, Renee (2016), "Tracking post-infectious fatigue in clinic using routine Lab tests.", BMC Pediatrics, 16 (54), doi:10.1186/s12887-016-0596-8
- ↑ Barkin, JA; Czul, F; Barkin, JS; Klimas, NG; Rey, IR; Moshiree, B (2016), "Gastric Enterovirus Infection: A Possible Causative Etiology of Gastroparesis", Digestive Diseases and Sciences, 61 (8): 2344-50, doi:10.1007/s10620-016-4227-x, PMID 27344315
- ↑ YouTube - nancy klimas
- ↑ http://www.investinme.eu/iimec12.shtml
- ↑ University of Miami ME/CFS Researcher Nancy Klimas, MD, Explains Complexity of Chronic Fatigue Syndrome in Terms That Anybody Can Understand