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Mutaflor
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'''Mutaflor®''' is a [[probiotic]] composed of ''[[Escherichia coli]]'' of the strain Nissle 1917. It is manufactured in Germany<ref>http://www.ardeypharm.de/</ref> and available in Canada<ref>http://mutaflor.ca/</ref> and several countries in Europe<ref>http://www.mutaflor.com/</ref> and Asia.<ref>http://mutaflor.sg/wp/</ref> It is available in Australia without prescription from selected pharmacies and medical dispensaries. <ref>http://mutaflor.com.au/</ref> New Zealand Pharmacies can supply Mutaflor® to a patient on request from an authorized prescriber based on Section 29 of the Medicines Act 1981.<ref>http://mutaflor.com.au/stockists/new-zealand/</ref> As of 2011, it is no longer available for distribution in the U.S., because of changes in the [[FDA]]'s rulings, known as the NDI (New Dietary Ingredient) guidelines that affects supplements and probiotics. Distributors outside the U.S. do not ship to the U.S. because of the FDA ruling.<ref>http://crohnsend.com/tag/fda/</ref><ref>http://www.fda.gov/RegulatoryInformation/Guidances/ucm257563.htm</ref> ==Mutaflor and ME/CFS== [[Ken Lassesen]] writes in [[Health Rising]] about using Mutafor as one of the treatments that led to his remission.<ref>http://www.healthrising.org/blog/2013/06/13/a-person-with-chronic-fatigue-syndrome-recovers-and-a-gut-series-begins/</ref> A possible rationale as reported by [[Ken Lassesen]] in his [[CFS Remission]] blog entry is as follows: "For CFS patients, several presentations at CFS conferences have reported that E.Coli population is very low in CFS patients, < 50% of controls. E.Coli produces NADH that is a precursor to Niacin (if you have niacin flushes, you are likely low on E.Coli). Niacin is a natural vascular dilator (keeps blood vessel wide/open), so its absence can result in reduced blood flow and brain fog."<ref>https://cfsremission.wordpress.com/treatment/microflora-and-autoimmune-illnesses/changing-microfloras-by-probiotics/mutaflor-escherichia-coli-nissle-1917/</ref> ==Learn more== *[https://en.wikipedia.org/wiki/Mutaflor Wikipedia - Mutaflor] *[http://www.drmyhill.co.uk/wiki/Growing_Mutaflor Dr Myhill - Growing Mutaflor] ==See also== *[[Probiotics]] *[[Microbiome]] ==References== {{Reflist}} [[Category:Potential treatments]] [[Category:Probiotics]] [[Category:Supplements]]
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