Muscle: Difference between revisions
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
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== | ==In ME and CFS== | ||
Several of the key symptoms observed by [[Melvin Ramsay]] and a part of his [[diagnostic criteria|Ramsay_definition]] involved '''muscle''' including [[muscle fatigability]] along with muscle [[pain]] and clumsiness ([[ataxia]]). Patients also complain of [[muscle fasciculations]]. | Several of the key symptoms observed by [[Melvin Ramsay]] and a part of his [[diagnostic criteria|Ramsay_definition]] involved '''muscle''' including [[muscle fatigability]] along with muscle [[pain]] and clumsiness ([[ataxia]]). Patients also complain of [[muscle fasciculations]]. | ||
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* Increased [[creatine kinase]] ([[postviral fatigue syndrome]]) | * Increased [[creatine kinase]] ([[postviral fatigue syndrome]]) | ||
* Persistence of [[enterovirus]]es in muscle tissue<ref name="Lindh1996"/><ref name="McGarry1994"/><ref name="Cunningham, 1990"/><ref name="Dowsett1990"/><ref name="Archard1988"/> | * Persistence of [[enterovirus]]es in muscle tissue<ref name="Lindh1996"/><ref name="McGarry1994"/><ref name="Cunningham, 1990"/><ref name="Dowsett1990"/><ref name="Archard1988"/> | ||
==See also== | |||
==Learn more== | |||
==References== |
Revision as of 19:13, June 23, 2018
In ME and CFS[edit | edit source]
Several of the key symptoms observed by Melvin Ramsay and a part of his Ramsay_definition involved muscle including muscle fatigability along with muscle pain and clumsiness (ataxia). Patients also complain of muscle fasciculations.
Numerous abnormalities have been found in the skeletal muscle of Myalgic Encephalomyelitis patients including:
- mitochondrial abnormalities found via muscle biopsy including: mitochondrial degeneration [1], deletions of mitochondrial DNA [2][3], the reduction of mitochondrial activity [2]
- Increased creatine kinase (postviral fatigue syndrome)
- Persistence of enteroviruses in muscle tissue[4][5][6][7][8]
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
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