Modra Murovska

Modra Murovska, MD, PhD, (b. 1949) is a researcher in virology, medical microbiology, and molecular biology; the Director of A. Kirchenstein Institute of Microbiology and Virology, Riga Stradins University, Riga, Latvia; and an Associate Professor at Riga Stradins University, Riga, Latvia. She is a member of the International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (IACFS/ME).

She is one of the authors of the 2011 case definition, International Consensus Criteria.

In 2009-2012, Dr. Murovska was assigned as Principle Investigator for the Latvian Council of Science in the investigation of etiopathogenesis of chronic fatigue syndrome, post-infection and unspecified origin encephalopathy and elaboration of diagnostic criterions.

Dr. Murovska chairs the Management Committee of the COST Action CA15111/EUROMENE and was the impetus to the program being started.

Education

• 1972, MD, Riga Medical Institute /Medical Academy of Latvia/ (Faculty of Pediatrics)
• 1978, Dr.med. (Candidate of Science in former USSR system, Ph.D. in Western countries), Cancer Research Centre, USSR Academy of Medical Sciences, Moscow, Russia

Studies

• 2016, Occurrence, phase and status of human parvovirus B19 infection in patients with myalgic encephalomyelitis/chronic fatigue syndrome

  "Conclusions: Results demonstrate finding of human parvovirus B19 persistent infection in active phase significantly more frequent and with higher B19 load among patients with ME/CFS than apparently healthy individuals indicating on implication of B19 infection in pathogenesis of ME/CFS. Therefore markers of active B19 infection could be used as one of biomarkers in ME/CFS diagnostics. Association of persistent B19 infection in active phase with part of typical ME/CFS clinical symptoms shows possible B19 involvement in disease development and reactivation of B19 may be a risk factor for ME/CFS. B19 infection statuses and onset of symptoms allow suggesting the feasible role of B19 infection as a trigger factor for ME/CFS./

• 2012, Association of active human herpesvirus-6, -7 and parvovirus B19 infection with clinical outcomes in patients with myalgic encephalomyelitis/chronic fatigue syndrome.
• 2006, Activation of human herpesviruses 6 and 7 in patients with chronic fatigue syndrome.

Online Presence

• Pubmed for Modra Murovska
• Latvian Scientists webpage

See Also

• HHV-6
• HHV-7
• EUROMENE
• IACFS/ME

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.