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Modafinil
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{{stub}} '''Modafinil''' is a non-stimulant medication used to improve wakefulness in adult patients with excessive sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder (SWD).<ref>{{Cite web|url=https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/020717s030s034s036MedGuide.pdf | title=Medication Guide | last = | first = | authorlink = | date = | website = U.S. Food & Drug Administration|archive-url=|archive-date=|url-status=|access-date=June 15, 2019|quote=}}</ref> In the United States, it is marketed with the name Provigil. ==Evidence== Modafinal is a suggested treatment for [[fatigue]] (increased energy and alertness) in the [[Canadian Consensus Criteria]], with 100mg suggested in the morning and adding another 100mg at noon.<ref name="canadianconsensus-CCC">{{Citation | last1 = Carruthers | first1 = Bruce M. | authorlink1 = Bruce Carruthers | last2 = Jain | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain | last3 = De Meirleir | first3 = Kenny L. | authorlink3 = Kenny De Meirleir | last4 = Peterson | first4 = Daniel L. | authorlink4 = Daniel Peterson | last5 = Klimas | first5 = Nancy G. | authorlink5 = Nancy Klimas | last6 = Lerner | first6 = A. Martin | authorlink6 = Martin Lerner | last7 = Bested | first7 = Alison C. | authorlink7 = Alison Bested | last8 = Flor-Henry | first8 = Pierre | authorlink8 = Pierre Flor-Henry | last9 = Joshi | first9 = Pradip | authorlink9 = Pradip Joshi | last10 = Powles | first10 = AC Peter | authorlink10 = A C Peter Powles | last11 = Sherkey | first11 = Jeffrey A. | authorlink11 = Jeffrey Sherkey | last12 = van de Sande | first12 = Marjorie I. | authorlink12 = Marjorie van de Sande | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols | journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | pages = 7-115 | date = 2003 | pmid = | doi = 10.1300/J092v11n01_02 | url = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf }}</ref> ==Notable studies == * 2000, Effect of Modafinil on Fatigue Associated with Neurological Illnesses<ref>{{Cite journal | last = Cochran | first = John W. | authorlink = | date = 2000 | title=Effect of Modafinil on Fatigue Associated with Neurological Illnesses|url=http://www.tandfonline.com/doi/full/10.1300/J092v08n02_06|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=8|issue=2 | pages = 65β70|doi=10.1300/J092v08n02_06|issn=1057-3321|quote=|via=}}</ref> == References == {{Reflist}} [[Category:Potential treatments]] [[Category:Central nervous system stimulants]]
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