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Michael VanElzakker
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[[File:Michael VanElZakker.png | thumb | Source: tufts.edu]] [[Michael VanElzakker]], Phd, is a neuroscientist affiliated at Massachusetts General Hospital, Harvard Medical School, and Tufts University. He has two primary research interests: [[Post-traumatic stress disorder | post traumatic stress disorder]] (PTSD), and [[chronic fatigue syndrome]] (CFS). He has proposed a [[vagus nerve infection hypothesis]] (VNIH) for [[ME/CFS]].<ref name = "VanElzakker2013"/> Dr. VanElzakker current research involves performing brain scans on [[ME/CFS]] patients and controls and analyzing the differences. ==Education and affiliations== '''Education''' *Univeristy of Colorado at Boulder - Bachelors's and Master's, Psychology/Behavioral Neuroscience *Tufts University - Doctor of Philosophy (PhD), Psychology: Psychiatric neuroscience - 2010 to 2015 *Harvard Medical School - Post Doctorate - 2015 to Present '''Affiliations''' *Neuroendocrinology Lab Manager - University of Colorado August 2004 β May 2010 *Massachusetts General Hospital - 2010 to Present ==Open letter to ''The Lancet''== Two [[open letter to the Lancet | open letters to the editor of ''The Lancet'']] urged the editor to commission a fully independent review of the [[PACE trial]], which the journal had published in 2011. In 2016, Dr. VanElzakker, along with 41 colleagues in the ME/CFS field, signed the second letter. *Feb 10, 2016, [http://www.virology.ws/2016/02/10/open-letter-lancet-again/ An open letter to The Lancet, again - Virology blog]<ref>{{Cite web | url = http://www.virology.ws/2016/02/10/open-letter-lancet-again/ | title = An open letter to The Lancet, again | last = Tuller | first = David | authorlink = David Tuller | date = Feb 10, 2016 | website = [[Virology blog]] | language = en-US | archive-url = | archive-date = | url-status = | access-date = 2018-10-14}}</ref> ==Notable studies== *2021, Corrigendum: Neuroinflammation and Cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Critical Review of Research Methods<ref name = "VanElzakker2021">{{Cite journal | title = Corrigendum: Neuroinflammation and Cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Critical Review of Research Methods | date = 2020 | url = https://www.frontiersin.org/articles/10.3389/fneur.2020.00863/full | journal = Frontiers in Neurology | volume = 11 | issue = | page = 863 | last = VanElzakker | first = Michael B. | authorlink = Michael VanElzakker | last2 = Brumfield | first2 = Sydney A. | author-link2 = | last3 = Lara Mejia | first3 = Paula S. | author-link3 = | language = English | doi = 10.3389/fneur.2020.00863/full | pmc = | pmid = 33041960 | issn = 1664-2295 | quote = | via = }}</ref> - [https://www.frontiersin.org/articles/10.3389/fneur.2020.00863/full (Full text)] *2021, Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms<ref name = "Proal2021">{{Cite journal | title = Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms | date = 2021 | url = https://www.frontiersin.org/articles/10.3389/fmicb.2021.698169/full | journal = Frontiers in Microbiology | volume = 12 | issue = | page = 698169 | last = Proal | first = Amy D. | authorlink = Amy Proal | last2 = VanElzakker | first2 = Michael B. | author-link2 = Michael VanElzakker | doi = 10.3389/fmicb.2021.698169 | pmc = | pmid = 3304196 | issn = 1664-302X | quote = | via = }}</ref> - [https://www.frontiersin.org/articles/10.3389/fmicb.2021.698169/full (Full text)] *2019, Neuroinflammation and cytokines in myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS): A critical review of research methods<ref>{{Cite journal | last = VanElzakker | first = Michael B. | authorlink = Michael VanElzakker | last2 = Brumfield | first2 = Sydney A. | author-link2 = Sydney Brumfield | last3 = Mejia | first3 = Paula S. Lara | author-link3 = Paula Lara Mejia | date = January 10, 2019 | title = Neuroinflammation and cytokines in myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS): A critical review of research methods | url = https://www.frontiersin.org/articles/10.3389/fneur.2018.01033/abstract | journal = Frontiers in Neurology | volume = 9 | issue = | page = 1033 | doi = 10.3389/fneur.2018.01033 | quote = | via = }}</ref> - [https://www.frontiersin.org/articles/10.3389/fneur.2018.01033/full (Full text)] *2013, Chronic fatigue syndrome from vagus nerve infection: A psychoneuroimmunological hypothesis<ref name = "VanElzakker2013">{{Cite journal | last = VanElzakker | first = Michael B. | date = 2013 | title = Chronic fatigue syndrome from vagus nerve infection: a psychoneuroimmunological hypothesis | pmid = 23790471 | journal = Medical Hypotheses | volume = 81 | issue = 3 | pages = 414β423 | doi = 10.1016/j.mehy.2013.05.034 | issn = 1532-2777 | url = https://www.pdf-archive.com/2013/06/23/vanelzakker-vnih-cfs-in-press/ | access-date = | archive-url = | archive-date = | url-status = | language = en | quote = }}</ref> - [http://www.pdf-archive.com/2013/06/23/vanelzakker-vnih-cfs-in-press/ (Full text)] ==Talks and interviews== *2014, [http://simmaronresearch.com/2014/02/michael-vanelzakker-ph-d-talks-vagus-nerve-infection-hypothesis-chronic-fatigue-syndrome-mecfs/ An Interview with Michael VanElzakker, Phd]<ref name = ":1">{{Cite news | url = http://simmaronresearch.com/2014/02/michael-vanelzakker-ph-d-talks-vagus-nerve-infection-hypothesis-chronic-fatigue-syndrome-mecfs/ | title = Michael VanElzakker Ph.d Talks β About the Vagus Nerve Infection Hypothesis and Chronic Fatigue Syndrome (ME/CFS) - Simmaron Research | last = Johnson | first = Cort | date = 2014-02-14 | work = Simmaron Research | access-date = 2018-10-14 | archive-url = | archive-date = | url-status = | language = en-US}}</ref> *2015, [http://thelowhistaminechef.com/harvard-neuroscientist-dr-michael-van-elzakker-chronic-fatigue-vagus-nerve-link/ Harvard neuroscientist Dr. Michael VanElZakker: Chronic fatigue vagus nerve link]<ref>{{Cite web | url = http://thelowhistaminechef.com/harvard-neuroscientist-dr-michael-van-elzakker-chronic-fatigue-vagus-nerve-link/ | title = Harvard neuroscientist Dr. Michael Van ElZakker: chronic fatigue vagus nerve link | last = Ykelenstam | first = Yasmina | date = 2015-12-08 | work = Healing Histamine | access-date = 2018-10-14 | archive-url = | archive-date = | url-status = | language = en-US}}</ref> *2015, [http://thelowhistaminechefpodcast.libsyn.com/chronic-fatigue-from-vagus-nerve-infection-a-psychoneuroimmunological-hypothesis Podcast interview on Chronic Fatigue from Vagus Nerve Infection]<ref>{{Cite web | url = http://thelowhistaminechefpodcast.libsyn.com/chronic-fatigue-from-vagus-nerve-infection-a-psychoneuroimmunological-hypothesis | title = Yasmina Ykelenstam's Healing Histamine Podcast: Chronic Fatigue from Vagus Nerve Infection: A Psychoneuroimmunological Hypothesis | last = Ykelenstam | first = Yasmina | date = Dec 7, 2015 | website = Yasmina Ykelenstam's Healing Histamine Podcast | archive-url = | archive-date = | url-status = | access-date = 2018-10-14 }}</ref> *2015, Appears in [[Forgotten Plague]] explaining his hypothesis *2016, [http://www.meaction.net/2016/12/12/dr-vanelzakker-two-new-mecfs-studies-at-harvard/ Dr VanElzakker: two new ME/CFS studies at Harvard] ::"Everyone here [at Harvard] recognizes that it's a neuroimmune condition and approaches it that way.... We don't have a test yet, therefore it's psychogenic? That reveals a tragic lack of humility about what we know and what we don't know."<ref name = ":0">{{Cite web | url = http://www.meaction.net/2016/12/12/dr-vanelzakker-two-new-mecfs-studies-at-harvard/ | title = Dr VanElzakker: two new ME/CFS studies at Harvard - #MEAction | last = Selzer | first = Jaime | date = 2016-12-12 | website = #MEAction | access-date = 2018-10-14 | archive-url = | archive-date = | url-status = | language = en-US}}</ref> *2017, [http://microbeminded.com/2017/12/07/interview-with-neuroscientist-michael-vanelzakker-vagus-nerve-mecfs-latent-infection-and-more/ Interview with neuroscientist Michael VanElzakker: Vagus Nerve, ME/CFS, latent infection and more]<ref>{{Cite web | url = http://microbeminded.com/2017/12/07/interview-with-neuroscientist-michael-vanelzakker-vagus-nerve-mecfs-latent-infection-and-more/ | title = Interview with neuroscientist Michael VanElzakker: Vagus Nerve, ME/CFS, latent infection and more | last = Proal | first = Amy | date = Dec 7, 2017 | website = Microbe Minded | language = en-US | archive-url = | archive-date = | url-status = | access-date = 2018-10-14}}</ref> * Mar 30, 2018, [https://www.youtube.com/watch?v=uO9j67WDYM4 ME/CFS Research with Michael VanElzakker, Vagus Nerve, triggers, ME/CFS Alert Episode 97]<ref>{{Cite web | url = https://www.youtube.com/watch?v=uO9j67WDYM4 | title = ME/CFS Research with Michael VanElzakker, Vagus Nerve, triggers {{!}} ME/CFS Alert Episode 97 | last = King | first = Llewellyn | date = Mar 30, 2018 | website = YouTube | archive-url = | archive-date = | url-status = | access-date = }}</ref> *Nov 15, 2018, [https://soundcloud.com/isabella-rosario-969685290/mecfs-fibromyalgia-the-sexist-truth-about-contested-illnesses ME/CFS, Fibromyalgia: The Sexist Truth about "Contested Illnesses"] interview by Isabella Rosario *May 31, [http://www.investinme.org/IIMEC14.shtm Ongoing study of physiological and fMRI measures before/after symptom provocation by invasive cardiopulmonary exercise testing] - 14th [[Invest in ME International ME Conference]]<ref>{{Cite web | url = http://www.investinme.org/IIMEC14.shtml | title = IIMEC14 14th Invest in ME Reseaerch International ME Conference 2019 | website = [[Invest in ME Research]] | access-date = 2020-02-17 }}</ref> - [https://www.youtube.com/watch?v=4ZBuD11ukCA (Video)] *Jun 8, 2019, [https://www.youtube.com/watch?v=bJ3UxSZ6MII&list=PLl4AfLZNZEQPNU0GYk3crnEnbQu_cYvO5&index=6 Neurology of ME/CFS: Neuroinflammation imaging], given at the Inaugural Harvard ME/CFS Collaboration Symposium sponsored by [[Open Medicine Foundation]] *Oct 26, 2019, [https://youtu.be/rIUccEITT6E ME/CFS at the Intersection of the Nervous & Immune Systems], [[Massachusetts ME/CFS & FM Association]] 2019 fall lecture *2022, [https://www.nbcboston.com/news/coronavirus/worst-hell-you-could-ever-imagine-study-hopes-to-shed-light-on-long-haul-covid/2617704/ 'Worst Hell You Could Ever Imagine': Study Hopes to Shed Light on Long-Haul COVID] - BBC Boston ==Quotes== === Cognitive behavioral therapy=== *On the topic of [[cognitive behavioral therapy]] (CBT): "I understand that this is a really charged topic among [[Chronic fatigue syndrome | CFS]] advocates, and there is a lot of misinformation out there. Just to be clear, cognitive-behavioral therapy (CBT) does not get at the root cause of CFS. [[Cognitive behavioral therapy|CBT]] offers coping strategies and is not a cure. But I can't think of a single medical condition that isn't exacerbated by stress. CFS is no different. Having a chronic illness is stressful and it makes one's life complicated and there's a grieving process. CBT is for those parts of the illness. It's intended to help people solve problems and to challenge dysfunctional patterns. If you're seeing a CBT practitioner who views CFS as a psychologically-based illness and is approaching your CBT that way, fire them. Find someone else."<ref name = ":1" /> *"Subjective measures of sick people before & after they are repeatedly told, "You're not sick" is a social psych study, not a clinical trial."<ref name="VanElzakker2016">{{cite tweet | last = VanElzakker | first = Michael | authorlink = Michael VanElzakker | title = Subjective measures of sick people before & after they are repeatedly told, "You're not sick" is a social psych study, not a clinical trial. | date = Aug 17, 2016 | user = MBvanelzakker | url = https://twitter.com/mbvanelzakker/status/765686260195332096 }}</ref> * "What #PACEtrial called "CBT" is not normal CBT. [[Cancer]] patients see CBT therapists all the time and are not told, 'you're not really sick.'"<ref>{{Cite tweet | url = https://twitter.com/MBVanElzakker/status/765678606425198592 | title = What #PACEtrial called "CBT" is not normal CBT. Cancer patients see CBT therapists all the time and are not told, 'you're not really sick.' | last = VanElzakker | first = Michael | date = Aug 16, 2016 | user = MBVanElzakker | access-date = 2018-10-14 | archive-url = | archive-date = }}</ref> ====Vagus nerve infection hypothesis==== *Quoting Louis Pasteur in reference to Vagus nerve infection hypothesis: "The germ is nothing; the terrain is everything."<ref>{{Cite tweet | url = https://twitter.com/MBVanElzakker/status/453540676635201536 | title = The germ is nothing; the terrain is everything. - Louis Pasteur | last = VanElzakker | first = Michael | authorlink = Michael VanElzakker | date = Apr 8, 2014 | user = MBVanElzakker | access-date = 2018-10-14 | archive-url = | archive-date = | url-status = }}</ref> ====Sex differences in neuropathic pain==== *"I've always seen glial cell action in neuropathic pain as a model for #VNIH. This paper elucidates sex differences:"<ref>{{Cite tweet | url = https://twitter.com/MBVanElzakker/status/775884625113743361 | title = I've always seen glial cell action in neuropathic pain as a model for #VNIH. This paper elucidates sex differences | last = VanElzakker | first = Michael | authorlink = Michael VanElzakker | date = Sep 13, 2016 | user = MBVanElzakker | access-date = 2018-10-14 | archive-url = | archive-date = | url-status = }}</ref> ::[https://www.nature.com/articles/tp2016168.pdf Glial contributions to visceral pain: implications for disease etiology and the female predominance of persistent pain]<ref name = "Dodds2016">{{Cite web | url = https://www.nature.com/articles/tp2016168.pdf | title = Glial contributions to visceral pain: implications for disease etiology and the female predominance of persistent pain | last = Dodds | first = KN | last2 = Beckett | first2 = EAH | date = 2016 | website = nature.com | publisher = | archive-url = | archive-date = | url-status = | access-date = | last3 = Evans | first3 = SF | last4 = Grace | first4 = PM | last5 = Watkins | first5 = LR | last6 = Hutchinson | first6 = MR}}</ref> * "Sex differences in #MECFS could be explained by sex differences in glial cell & vagus nerve function." #VNIH.<ref>{{Cite tweet | url = https://twitter.com/MBVanElzakker/status/776506826070327296 | authorlink = Michael VanElzakker | title = Sex differences in #MECFS could be explained by sex differences in glial cell & vagus nerve function. | last = VanElzakker | first = Michael | date = Sep 15, 2016 | user = MBVanElzakker | access-date = 2018-10-14 | archive-url = | archive-date = | url-status = }}</ref><ref name = "Dodds2016" /> ==Online presence== *[https://www.researchgate.net/profile/Michael-Vanelzakker Researchgate] *[https://www.linkedin.com/in/michael-vanelzakker-9930726 LinkedIn] *[http://www.ncbi.nlm.nih.gov/pubmed/?term=Van%20Elzakker%20M%5BAuthor%5D&cauthor=true&cauthor_uid=12722974 PubMed] *[https://twitter.com/MBVanElzakker Twitter] ==See also== *[[Vagus nerve infection hypothesis]] *[[Vagus nerve]] *[[Polybio Research Foundation|PolyBio Research Foundation]] ==Learn more== *[https://as.tufts.edu/psychology/people/faculty/michael-vanelzakker Tufts faculty profile] *[https://connects.catalyst.harvard.edu/Profiles/display/Person/142345 Harvard Catalyst] *[https://mgriblog.org/2018/09/19/postdoc-profile-michael-vanelzakker-phd/ Postdoc Profile] - MGH Research (2018) ==References== {{Reflist}} [[Category:Researchers]] [[Category:US researchers]] [[Category:Psychological paradigm critics]] [[Category:PACE trial critics]]
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