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Matrix metalloproteinase
(section)
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=== Potential MMP inhibitors === * [[doxycycline]]<ref name=":0">{{Cite journal | last = De Paiva | first = Cintia S. | last2 = Corrales | first2 = Rosa M. | last3 = Villarreal | first3 = Arturo L. | last4 = Farley | first4 = William J. | last5 = Li | first5 = De-Quan | last6 = Stern | first6 = Michael E. | last7 = Pflugfelder | first7 = Stephen C. | date = 2006-09-01 | title = Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye|url=http://www.sciencedirect.com/science/article/pii/S0014483506001709|journal=Experimental Eye Research|volume=83|issue=3 | pages = 526–535|doi=10.1016/j.exer.2006.02.004|issn=0014-4835}}</ref><ref>{{Cite journal | last = Roach|first = D. M | last2 = Fitridge | first2 = R. A | last3 = Laws | first3 = P. E | last4 = Millard | first4 = S. H | last5 = Varelias | first5 = A | last6 = Cowled | first6 = P. A | date = 2002-03-01 | title = Up-regulation of MMP-2 and MMP-9 Leads to Degradation of Type IV Collagen During Skeletal Muscle Reperfusion Injury; Protection by the MMP Inhibitor, Doxycycline|url=http://www.sciencedirect.com/science/article/pii/S1078588402915984|journal=European Journal of Vascular and Endovascular Surgery|volume=23|issue=3|pages=260–269|doi=10.1053/ejvs.2002.1598|issn=1078-5884}}</ref><ref>{{Cite journal | last = Niedzwiecki|first = A. | last2 = Rath | first2 = M. | last3 = Kalinovsky | first3 = T. | last4 = Monterrey | first4 = J.C. | last5 = Roomi | first5 = M.W. | date = 2010-03-01 | title = In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors|url=http://www.spandidos-publications.com/or/23/3/605/abstract|journal=Oncology Reports|volume=23|issue=3 | pages = 605–614|doi=10.3892/or_00000675|issn=1021-335X}}</ref><ref>{{Cite journal | last = Choi|first = Dong-Hoon | last2 = Moon | first2 = Ik-Sang | last3 = Choi | first3 = Bong-Kyu | last4 = Paik | first4 = Jeong-Won | last5 = Kim | first5 = Yoon-Sik | last6 = Choi | first6 = Seong-Ho | last7 = Kim | first7 = Chong-Kwan | date = 2004 | title = Effects of sub-antimicrobial dose doxycycline therapy on crevicular fluid MMP-8, and gingival tissue MMP-9, TIMP-1 and IL-6 levels in chronic periodontitis|url=https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0765.2004.00696.x|journal=Journal of Periodontal Research|language=en|volume=39|issue=1|pages=20–26|doi=10.1111/j.1600-0765.2004.00696.x|issn=1600-0765}}</ref><ref>{{Cite journal | last = Li|first = De-Quan | last2 = Lokeshwar | first2 = Balakrishna L | last3 = Solomon | first3 = Abraham | last4 = Monroy | first4 = Dagoberto | last5 = Ji | first5 = Zhonghua | last6 = Pflugfelder | first6 = Stephen C | date = 2001-10-01 | title = Regulation of MMP-9 Production by Human Corneal Epithelial Cells|url=http://www.sciencedirect.com/science/article/pii/S0014483501910541|journal=Experimental Eye Research|volume=73|issue=4 | pages = 449–459|doi=10.1006/exer.2001.1054|issn=0014-4835}}</ref><ref>{{Cite journal | last = Brown David L. | last2 = Desai Kavita K. | last3 = Vakili Babak A. | last4 = Nouneh Chadi | last5 = Lee Hsi-Ming | last6 = Golub Lorne M. | date = 2004-04-01 | title = Clinical and Biochemical Results of the Metalloproteinase Inhibition with Subantimicrobial Doses of Doxycycline to Prevent Acute Coronary Syndromes (MIDAS) Pilot Trial|url=https://www.ahajournals.org/doi/full/10.1161/01.ATV.0000121571.78696.dc|journal=Arteriosclerosis, Thrombosis, and Vascular Biology|volume=24|issue=4 | pages = 733–738|doi=10.1161/01.ATV.0000121571.78696.dc}}</ref> (contrary results<ref>{{Cite journal | last = Górska | first = Renata | last2 = Nędzi-Góra | first2 = Małgorzata | date = 2006-12-01 | title = The effects of the initial treatment phase and of adjunctive low-dose doxycycline therapy on clinical parameters and MMP-8, MMP-9, and TIMP-1 levels in the saliva and peripheral blood of patients with chronic periodontitis|url=https://doi.org/10.1007/s00005-006-0047-6|journal=Archivum Immunologiae et Therapiae Experimentalis|language=en|volume=54|issue=6 | pages = 419–426|doi=10.1007/s00005-006-0047-6|issn=1661-4917}}</ref>) * [[Corticosteroid|Corticosteroids]]<ref name=":0" />
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