Marcie Zinn: Difference between revisions

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==Talks & interviews==
==Talks & interviews==
*2016 - [https://www.youtube.com/watch?v=aN0Fh0kiUiI "qEEG LORETA CFS Case study - Sci Forschen Inc."] with Leonard Jason, Marcie Zinn, and Mark Zinn


==Online presence==
==Online presence==

Revision as of 18:37, April 24, 2017

Marcie L. Zinn, Ph.D., (born 1951) is an experimental psychologist conducting myalgic encephalomyelitis (ME) research with her husband, Mark Zinn, and Dr. Leonard Jason at the DePaul Center for Community Research. Marcie's research interests include the study of myalgic encephalomyelitis as well as Performing Arts Neuroscience and Psychology. Her early research and career interests were in Performance Neuroscience and Psychology, but after being diagnosed in 2009 with viral encephalitis which became Myalgic Encephalomyelitis, her interest turned toward using her extensive qEEG and neuroscience skills for research in ME. Under the leadership of Dr. Jose Montoya, she conducted a pilot study to look at cognitive dysfunction using qEEG methods. She and her husband Mark have recently moved to Chicago to work with Dr. Leonard Jason and have published four articles, all of which illustrate qEEG methods in the study of ME brain dysfunction.

Open Letter to The Lancet[edit | edit source]

Two open letters to the editor of The Lancet urged the editor to commission a fully independent review of the PACE trial, which the journal had published in 2011. In 2016, Dr. Zinn, along with 41 colleagues in the ME/CFS field, signed the second letter.

Notable studies[edit | edit source]

  • 2016, Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study (FULL TEXT)

    Abstract - Exact low resolution electromagnetic tomography (eLORETA) was recorded from nineteen EEG channels in nine patients with myalgic encephalomyelitis (ME) and 9 healthy controls to assess current source density and functional connectivity, a physiological measure of similarity between pairs of distributed regions of interest, between groups. Current source density and functional connectivity were measured using eLORETA software. We found significantly decreased eLORETA source analysis oscillations in the occipital, parietal, posterior cingulate, and posterior temporal lobes in Alpha and Alpha-2. For connectivity analysis, we assessed functional connectivity within Menon triple network model of neuropathology. We found support for all three networks of the triple network model, namely the central executive network (CEN), salience network (SN), and the default mode network (DMN) indicating hypo-connectivity in the Delta, Alpha, and Alpha-2 frequency bands in patients with ME compared to controls. In addition to the current source density resting state dysfunction in the occipital, parietal, posterior temporal and posterior cingulate, the disrupted connectivity of the CEN, SN, and DMN appears to be involved in cognitive impairment for patients with ME. This research suggests that disruptions in these regions and networks could be a neurobiological feature of the disorder, representing underlying neural dysfunction.[1]

  • 2016, qEEG / LORETA in Assessment of Neurocognitive Impairment in a Patient with Chronic Fatigue Syndrome: A Case Report (Marcie Zinn, Mark Zinn, Leonard Jason)
  • 2015, Myalgic Encephalomyelitis: Symptoms and Biomarkers. (Marcie Zinn, Mark Zinn, Leonard Jason)

Talks & interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Zinn, Marcie; Zinn, Mark; Jason, Leonard (2016), "Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study", Applied Psychophysiology and Biofeedback, 41 (3): 283-300, doi:10.1007/s10484-016-9331-3, PMID 26869373