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'''Marcie Lynn Zinn''' Ph.D. (May 6, 1951- Dec 28, 2019) was a research psychologist in Psychophysiology, Rehabilitation, Cognitive Neuroscience and Data Science conducting [[myalgic encephalomyelitis]] (ME) and [[chronic fatigue syndrome]] (CFS) research with her husband, [[Mark Zinn]], at their nonprofit, the [[Neurocognitive Research Institute]]. Dr Zinn's research interests included the study of brain dysfunction in chronic disease, such as [[myalgic encephalomyelitis]] (M.E.). Marcie and her husband, Mark Zinn, also founded the NeuroCognitive Research Institute.  Marcie Zinn passed away suddenly from sudden heart failure<ref>{{Cite web|url=https://www.kaminskifamilyfuneralhomes.com/obituary/dr-marcie-zinn-phd | title = Dr. Marcie Zinn, Ph.D. {{!}} Kaminski Family | website = kaminskifamilyfuneralhomes.com|language=en|access-date=2020-01-10}}</ref> while working to establish the NeuroCognitive Research Institute.<ref>{{Cite web|url=https://www.gofundme.com/f/the-ncri-needs-your-support | title = Click here to support Marcie Zinn Memorial Fund organized by Mark Zinn, Ph.D. |website=gofundme.com|language=en|access-date=2020-01-09}}</ref>
'''Marcie L. Zinn''', Ph.D., (born 1951) is an experimental psychologist conducting [[myalgic encephalomyelitis]] (ME) research with her husband, [[Mark Zinn]], and Dr. [[Leonard Jason]] at the DePaul Center for Community Research. Marcie's research interests include the study of [[myalgic encephalomyelitis]] as well as Performing Arts Neuroscience and Psychology. Her early research and career interests were in Performance Neuroscience and Psychology, but after being diagnosed in 2009 with viral encephalitis which became Myalgic Encephalomyelitis, her interest turned toward using her extensive qEEG and neuroscience skills for research in ME. Under the leadership of Dr. [[Jose Montoya]], she conducted a pilot study to look at cognitive dysfunction using qEEG methods. She and her husband Mark have recently moved to Chicago to work with Dr. Leonard Jason and have published four articles, all of which illustrate qEEG methods in the study of ME brain dysfunction.
Dr Zinn's early research and career interests were in Performance Neuroscience and Psychology, but after being diagnosed in 2009 with herpes viral encephalitis which developed into [[Myalgic Encephalomyelitis]], her interest turned toward using her extensive [[QEEG|qEEG]] and neuroscience skills for research in [[myalgic encephalomyelitis|M.E.]]. Under the leadership of Dr. [[Jose Montoya]], she conducted a pilot study to look at cognitive dysfunction using [[QEEG|qEEG]] methods. While continuing to collaborate with Jose Montoya at Stanford, she and her husband [[Mark Zinn|Mark]] published research using brain network modeling in the study of M.E. [[brain]] dysfunction.<ref name="meet">{{Cite web
|work=MEE Medical|publisher =[[ME Association]]|url = https://meassociation.org.uk/wp-content/uploads/MEE-MEDICAL-MAGAZINE-AUTUMN-2021.pdf | pages=12-13| title = Meet the Scientist: Central Autonomic Network Disturbance in people with ME/CFS {{!}} A conversation with Dr. Mark Zinn | first = Dylan |last =Murphy | date =Autumn 2021}}</ref>


==Open Letter to ''The Lancet''==  
==ME/CFS Common Data Element (CDE) Project==
Two [[open letter to the Lancet | open letters to the editor of ''The Lancet'']] urged the editor to commission a fully independent review of the [[PACE]] trial, which the journal had published in 2011. In 2016, Dr. Zinn, along with 41 colleagues in the [[ME/CFS]] field, signed the second letter.
Marcie Zinn was a member of the Pain Working Group and the Neurologic/Cognitive/CNS Imaging Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the [[National Institute of Neurological Disorders and Stroke]] and the [[Centers for Disease Control and Prevention]].<ref>{{Cite web|url=https://www.commondataelements.ninds.nih.gov/Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome#pane-138 | title = Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster | last = | first = | authorlink = | date = | website = NIH|archive-url=|archive-date=|url-status=|access-date=2019-10-11}}</ref>
*10 February 2016, [http://www.virology.ws/2016/02/10/open-letter-lancet-again/ An open letter to The Lancet, again - Virology blog]
 
==Advocacy==
* Dr. Zinn signed the second and third [[open letter to the Lancet|open letters to the editor of ''The Lancet'']] urging the editor to commission a fully independent review of the [[PACE trial]], which the journal published in 2011.<ref>{{Cite web|url=http://www.virology.ws/2016/02/10/open-letter-lancet-again/ | title = An open letter to The Lancet, again|website=[[Virology blog]]|access-date=2019-12-03}}</ref><ref>{{Cite web|url=http://www.virology.ws/2018/06/19/trial-by-error-an-open-letter-to-the-lancet-two-years-on/ | title = Trial By Error: An Open Letter to The Lancet, Two Years On|website=[[Virology blog]]|language=en-US|access-date=2019-12-03}}</ref>
* Feb 10, 2016, [http://www.virology.ws/2016/02/10/open-letter-lancet-again/ An open letter to The Lancet, again - Virology blog]
* Jun 19, 2018, [http://www.virology.ws/2018/06/19/trial-by-error-an-open-letter-to-the-lancet-two-years-on/ Trial By Error: An Open Letter to The Lancet, Two Years On - Virology blog]  


==Notable studies==
==Notable studies==
*2016 - Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study [https://www.researchgate.net/publication/294258397_Intrinsic_Functional_Hypoconnectivity_in_Core_Neurocognitive_Networks_Suggests_Central_Nervous_System_Pathology_in_Patients_with_Myalgic_Encephalomyelitis_A_Pilot_Study (FULL TEXT)] <blockquote> Abstract - Exact low resolution electromagnetic tomography (eLORETA) was recorded from nineteen EEG channels in nine patients with myalgic encephalomyelitis (ME) and 9 healthy controls to assess current source density and functional connectivity, a physiological measure of similarity between pairs of distributed regions of interest, between groups. Current source density and functional connectivity were measured using eLORETA software. We found significantly decreased eLORETA source analysis oscillations in the occipital, parietal, posterior cingulate, and posterior temporal lobes in Alpha and Alpha-2. For connectivity analysis, we assessed functional connectivity within Menon triple network model of neuropathology. We found support for all three networks of the triple network model, namely the central executive network (CEN), salience network (SN), and the default mode network (DMN) indicating hypo-connectivity in the Delta, Alpha, and Alpha-2 frequency bands in patients with ME compared to controls. In addition to the current source density resting state dysfunction in the occipital, parietal, posterior temporal and posterior cingulate, the disrupted connectivity of the CEN, SN, and DMN appears to be involved in cognitive impairment for patients with ME. This research suggests that disruptions in these regions and networks could be a neurobiological feature of the disorder, representing underlying neural dysfunction.<ref name="Zinn, 2016"/></blockquote>
* June, 2004: ''Development of a Self-Report Inventory to Assess Cognitive Dysfunction in Musicians.'' ProQuest Information and Learning Company, Ann Arbor, Michigan. 
*2016 - qEEG / LORETA in Assessment of Neurocognitive Impairment in a Patient with Chronic Fatigue Syndrome: A Case Report [https://sciforschenonline.org/journals/clinical-research/CLROA-2-110.php (FULL TEXT)] <blockquote> Abstract - Importance: Chronic Fatigue Syndrome (CFS) is a chronic disease resulting in considerable and widespread cognitive deficits. Accurate and accessible measurement of the extent and nature of these deficits can aid healthcare providers and researchers in the diagnosis of this condition, choosing interventions and tracking treatment effects. Here, we present a case of a middle-aged man diagnosed with CFS which began following a typical viral illness. Observations: LORETA source density measures of surface EEG connectivity at baseline were performed on 3 minutes of eyes closed deartifacted19-channel qEEG. The techniques used to analyze the data are described along with the hypothesized effects of the deregulation found in this data set. Nearly all (>90%) patients with CFS complain of cognitive deficits such as slow thinking, difficulty in reading comprehension, reduced learning and memory abilities and an overall feeling of being in a “fog.”Therefore, impairment may be seen in deregulated connections with other regions (functional connectivity); this functional impairment may serve as one cause of the cognitive decline in CFS. Here, the functional connectivity networks of this patient were sufficiently deregulated to cause the symptoms listed above. Conclusions and significance: This case report increased our understanding of CFS from the perspective of brain functional networks by offering some possible explanations for cognitive deficits in patients with CFS. There are only a few reports of using source density analysis or qEEG connectivity analysis for cognitive deficits in CFS. While no absolute threshold exists to advise the physician as to when to conduct such analyses, the basis of his or her decision whether or not to use these tools should be a function of clinical judgment and experience. These analyses may potentially aid in clinical diagnosis, symptom management, treatment response and can alert the physician as to when intervention may be warranted.<ref name="Zinn ML, 2016"/></blockquote>
* March, 2005: ''The Hippocampus in Music Learning and Performance'' (March, 2005). Presentation at the annual Brain Awareness Week event sponsored by Dana Alliance for Brain Initiatives, Dublin, CA. 
*2016 - Functional Neural Network Connectivity in Myalgic Encephalomyelitis [https://www.researchgate.net/publication/297453164_NeuroRegulation_httpwwwisnrorg_Functional_Neural_Network_Connectivity_in_Myalgic_Encephalomyelitis (FULL TEXT)]<blockquote> Abstract - Myalgic Encephalomyelitis (ME) is a chronic illness with debilitating neurocognitive impairment that remains poorly understood. Previous studies have characterized cognitive deficits as a process by which brain abnormalities are inferred from pre-established testing paradigms using neuroimaging with low temporal resolution. Unfortunately, this approach has been shown to provide limited predictive power, rendering it inadequate for the study of neuronal communication between synchronized regions. More recent developments have highlighted the importance of modeling spatiotemporal dynamic interactions within and between large-scale and small-scale neural networks on a millisecond time scale. Here, we focus on recent emergent principles of complex cortical systems, suggesting how subtle disruptions of network properties could be related to significant disruptions in cognition and behavior found in ME. This review, therefore, discusses how electrical neuroimaging methods with time-dependent metrics (e.g., coherence, phase, cross-frequency coupling) can be a useful approach for the understanding of the cognitive symptoms in ME. By providing a platform for utilizing real-time alterations of the perpetual signals as an outcome, the disruptions to higher-level cognition typically seen in ME can be readily identified, creating new opportunities for better diagnosis and targeted treatments.<ref name="Zinn&Zinn, 2016"/></blockquote>
* Mar 2014, Cortical hypoactivation during resting eLORETA suggests central nervous system pathology in patients with chronic fatigue syndrome (Conference paper, 2014 Stanford Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Symposium: Advances in Clinical Care and Translational Research for health care providers, Stanford School of Medicine, Palo Alto, CA<ref>{{Cite journal|last = Zinn | first = Mark | authorlink = Mark Zinn | last2 = Zinn | first2 = Marcie | authorlink2 = Marcie Zinn | last3 = Maldonado | first3 = Jose R | authorlink3 = | last4 = Norris | first4 = Jane L | authorlink4 = Jane Norris | last5 = Valencia | first5 = Ian J. | authorlink5 = Ian Valencia | last6 = Montoya | first6 = Jose G  | authorlink6 = Jose Montoya | date = 2014-03-18 | title = Cortical hypoactivation during resting eLORETA suggests central nervous system pathology in patients with chronic fatigue syndrome|url=https://www.researchgate.net/publication/290628295_Cortical_hypoactivation_during_resting_eLORETA_suggests_central_nervous_system_pathology_in_patients_with_chronic_fatigue_syndrome|journal=2014 Stanford Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Symposium Conference Paper|volume=|issue=|pages=|doi=|pmc=|pmid=|access-date=2019-12-03|quote=|via=}}</ref> - [https://www.researchgate.net/publication/290628295_Cortical_hypoactivation_during_resting_eLORETA_suggests_central_nervous_system_pathology_in_patients_with_chronic_fatigue_syndrome (Abstract - full text on request)
*2015 - Myalgic Encephalomyelitis: Symptoms and Biomarkers [http://www.ncbi.nlm.nih.gov/pubmed/26411464 (FULL TEXT)] <blockquote> Abstract - Myalgic Encephalomyelitis (ME) continues to cause significant morbidity worldwide with an estimated one million cases in the United States. Hurdles to establishing consensus to achieve accurate evaluation of patients with ME continue, fueled by poor agreement about case definitions, slow progress in development of standardized diagnostic approaches, and issues surrounding research priorities. Because there are other medical problems, such as early MS and Parkinson’s Disease, which have some similar clinical presentations, it is critical to accurately diagnose ME to make a differential diagnosis. In this article, we explore and summarize advances in the physiological and neurological approaches to understanding, diagnosing, and treating ME. We identify key areas and approaches to elucidate the core and secondary symptom clusters in ME so as to provide some practical suggestions in evaluation of ME for clinicians and researchers. This review, therefore, represents a synthesis of key discussions in the literature, and has important implications for a better understanding of ME, its biological markers, and diagnostic criteria. There is a clear need for more longitudinal studies in this area with larger data sets, which correct for multiple testing.<ref name="Jason,Zinn, 2015"/></blockquote>
* Mar 2014,  ''EEG peak alpha frequency is associated with chronic fatigue syndrome: a case-control observational study''. Invited presentation at the 2014 Stanford Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Symposium : Advances in Clinical Care and Translational Research; March 19, 2014, Stanford University Dept. of Medicine, Palo Alto, CA.    
*2015, Myalgic Encephalomyelitis: Symptoms and [[Biomarker]]s<ref>{{Cite web|url=http://www.eurekaselect.com/135207/article | title = Myalgic Encephalomyelitis: Symptoms and Biomarkers | last = Jason | first = Leonard A. | authorlink = Leonard Jason | last2 = Zinn | first2 = Marcie L. | authorlink2 = Marcie Zinn | date = 2015-08-31 | website = Current Neuropharmacology|language=en|doi=10.2174/1570159x13666150928105725|pmc=4761639|pmid=26411464|archive-url=|archive-date=|url-status=|access-date=2019-12-03 | last3 = Zinn | first3 = Mark A. | authorlink3 = Mark Zinn}}</ref> - [http://www.ncbi.nlm.nih.gov/pubmed/26411464 (Full Text)]
*2015,  Zinn, M.L. & Zinn, M.A. Psychophysiology for Performing Artists. In M. S. Schwartz & F. Andrasik, Eds: Biofeedback: A Practitioners Guide (4th ed.), New York: Guilford.
*2016, Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with [[Myalgic Encephalomyelitis]]: A Pilot Study<ref>{{Cite journal|last = Zinn | first = Marcie L. | authorlink = Marcie Zinn | last2 = Zinn | first2 = Mark A. | authorlink2 = Mark Zinn | last3 = Jason | first3 = Leonard A. | authorlink3 = Leonard Jason | date = Sep 2016 | title = Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study|url=http://link.springer.com/10.1007/s10484-016-9331-3|journal=Applied Psychophysiology and Biofeedback|language=en|volume=41|issue=3|pages=283–300|doi=10.1007/s10484-016-9331-3|issn=1090-0586|pmc=|pmid=|access-date=|quote=|via=}}</ref> - [https://www.researchgate.net/publication/294258397_Intrinsic_Functional_Hypoconnectivity_in_Core_Neurocognitive_Networks_Suggests_Central_Nervous_System_Pathology_in_Patients_with_Myalgic_Encephalomyelitis_A_Pilot_Study (Full Text)]
*2016, [[QEEG|qEEG]] / LORETA in Assessment of Neurocognitive Impairment in a Patient with Chronic Fatigue Syndrome: A Case Report<ref>{{Cite journal|last = Marcie L | first = Zinn | authorlink = Marcie Zinn | last2 = Zinn | first2 = Mark A  | authorlink2 = Mark Zinn | last3 = Jason | first3 = Leonard A  | authorlink3 = Leonard Jason | date = 2016 | title=qEEG / LORETA in Assessment of Neurocognitive Impairment in a Patient with Chronic Fatigue Syndrome: A Case Report|url=https://www.sciforschenonline.org/journals/clinical-research/CLROA-2-110.php|journal=Clinical Research: Open Access ( ISSN 2469-6714 )|volume=2|issue=1|pages=|doi=10.16966/2469-6714.110|pmc=|pmid=|access-date=|quote=|via=}}</ref> - [https://sciforschenonline.org/journals/clinical-research/CLROA-2-110.php (Full Text)]
*2016, Functional Neural Network Connectivity in Myalgic Encephalomyelitis<ref>{{Cite journal|last = Zinn | first = Marcie | authorlink = Marcie Zinn | last2 = Zinn | first2 = Mark  | authorlink2 = Mark Zinn | last3 = Jason | first3 = Leonard | authorlink3 = Leonard Jason | date = 2016-03-09 | title = Functional Neural Network Connectivity in Myalgic Encephalomyelitis|url=http://www.neuroregulation.org/article/view/16018|journal=NeuroRegulation|volume=3|issue=1|pages=28–50|doi=10.15540/nr.3.1.28|pmc=|pmid=|access-date=|quote=|via=}}</ref> - [https://www.researchgate.net/publication/297453164_NeuroRegulation_httpwwwisnrorg_Functional_Neural_Network_Connectivity_in_Myalgic_Encephalomyelitis (Full Text)]
*2017, Small-world network analysis of cortical connectivity in [[Chronic Fatigue Syndrome]] using quantitative [[EEG]]<ref>{{Cite journal|last = Zinn | first = Mark Alan | authorlink = Mark Zinn | last2 = Zinn | first2 = Marcie L. | authorlink2 = Marcie Zinn | last3 = Jason | first3 = Leonard A. | authorlink3 = Leonard Jason | date = 2017-12-07 | title = Small-World Network Analysis of Cortical Connectivity in Chronic Fatigue Syndrome Using Quantitative EEG|url=http://www.neuroregulation.org/article/view/17838|journal=NeuroRegulation|language=en|volume=4|issue=3-4|pages=125|doi=10.15540/nr.4.3-4.125|issn=2373-0587|via=}}</ref> - [https://www.researchgate.net/publication/321717868_Small-World_Network_Analysis_of_Cortical_Connectivity_in_Chronic_Fatigue_Syndrome_Using_Quantitative_EEG (Full Text)]
*2018, Cortical hypoactivation during resting EEG suggests central nervous system pathology in patients with [[chronic fatigue syndrome]]<ref>{{Cite journal|last = Zinn | first = M.A. | authorlink = Mark Davis | last2 = Zinn | first2 = M.L. | authorlink2 = Marcie Zinn | last3 = Valencia | first3 = I. | authorlink3 = Ian Valencia | last4 = Jason | first4 = L.A. | authorlink4 = Leonard Jason | last5 = Montoya | first5 = J.G. | authorlink5 = Jose Montoya | date = Jul 2018 | title = Cortical hypoactivation during resting EEG suggests central nervous system pathology in patients with chronic fatigue syndrome|url=https://linkinghub.elsevier.com/retrieve/pii/S0301051118304071|journal=Biological Psychology|language=en|volume=136|issue= | pages = 87–99|doi=10.1016/j.biopsycho.2018.05.016|pmc=|pmid=29802861|quote=|via=}}</ref> - [https://www.sciencedirect.com/science/article/pii/S0301051118304071 (Abstract)]


==Talks & interviews==
==Talks and interviews==
*2016 - [https://www.youtube.com/watch?v=aN0Fh0kiUiI "qEEG LORETA CFS Case study - Sci Forschen Inc."] with Leonard Jason, Marcie Zinn, and Mark Zinn
*2016, [https://www.youtube.com/watch?v=aN0Fh0kiUiI "qEEG LORETA CFS Case study - Sci Forschen Inc."]


==Online presence==
==Online presence==
Line 21: Line 34:


==Learn more==
==Learn more==
*[https://meassociation.org.uk/wp-content/uploads/MEE-MEDICAL-MAGAZINE-AUTUMN-2021.pdf Meet the Scientist: Central Autonomic Network Disturbance in people with ME/CFS {{!}} A conversation with Dr. Mark Zinn] (p. 12-13)
*[http://www.selfgrowth.com/experts/marcie_zinn.html "Marcie Zinn Ph.D., NCTM" bio]
*[http://www.selfgrowth.com/experts/marcie_zinn.html "Marcie Zinn Ph.D., NCTM" bio]
*[https://www.thencri.org NeuroCognitive Research Institute]


==See also==
==See also==
*[[Mark Zinn]]
*[[Mark Zinn]]
*[[Leonard Jason]]
*[[qEEG|eLORETA]]
*[[qEEG]]


==References==
==References==
<references>
{{reflist}}
<ref name="Zinn, 2016">
{{Citation
| last1  = Zinn                  | first1 = Marcie                  | authorlink1 = Marcie Zinn
| last2  = Zinn                  | first2 =  Mark                    | authorlink2 = Mark Zinn
| last3  = Jason                | first3 = Leonard                  | authorlink3 = Leonard Jason
| title  = Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study
| journal = Applied Psychophysiology and Biofeedback  | volume = 41  | issue = 3  | page = 283-300
| date    = 2016
| pmid    = 26869373
| doi    = 10.1007/s10484-016-9331-3
}}
</ref>
<ref name="Zinn ML, 2016">
{{Citation
| last1  = Zinn                  | first1 = Marcie                  | authorlink1 = Marcie Zinn
| last2  = Zinn                  | first2 =  Mark                    | authorlink2 = Mark Zinn
| last3  = Jason                | first3 = Leonard                  | authorlink3 = Leonard Jason
| title  = qEEG / LORETA in Assessment of Neurocognitive Impairment in a Patient with Chronic Fatigue Syndrome: A Case Report
| journal = Clinical Research: Open Access  | volume = 2  | issue = 1  | page =
| date    = 2016
| pmid    = 26869373
| doi    = 10.16966/2469-6714.110
}}
</ref>
<ref name="Zinn&Zinn, 2016">
{{Citation
| last1  = Zinn                  | first1 = Marcie                  | authorlink1 = Marcie Zinn
| last2  = Zinn                  | first2 =  Mark                    | authorlink2 = Mark Zinn
| last3  = Jason                | first3 = Leonard                  | authorlink3 = Leonard Jason
| title  = Functional Neural Network Connectivity in Myalgic Encephalomyelitis
| journal = NeuroRegulation  | volume = 3  | issue = 1  | page = 28-50
| date    = 2016
| pmid    =
| doi    = 10.15540/nr.3.1.28
}}
</ref>
<ref name="Jason,Zinn, 2015">
{{Citation
| last1  = Jason                | first1 = Leonard                  | authorlink1 = Leonard Jason
| last2  = Zinn                  | first2 = Marcie                  | authorlink2 = Marcie Zinn
| last3  = Zinn                  | first3 =  Mark                    | authorlink3 = Mark Zinn
| title  = Myalgic Encephalomyelitis: Symptoms and Biomarkers
| journal = Current Neuropharmacology  | volume = 13  | issue = 5  | page = 701-34.
| date    = 2015
| pmid    = 26411464
| doi    = 10.2174/1570159X13666150928105725
}}
</ref>
</references>


[[Category:Researchers]]
[[Category:Researchers]]
[[Category:USA researchers]]
[[Category:Clinicians]]
[[Category:US researchers]]
[[Category:People with ME, CFS, and/or FMS]]
[[Category:People with ME, CFS, and/or FMS]]
[[Category:Psychological paradigm critics]]
[[Category:Psychological paradigm critics]]
[[Category:PACE trial critics]]
[[Category:PACE trial critics]]
[[Category:Deceased people with ME, CFS, and/or FMS]]
[[Category:Famous people with ME, CFS, and/or FMS]]
[[Category:American famous people with ME, CFS, and/or FMS]]

Latest revision as of 16:27, April 3, 2023

Marcie Lynn Zinn Ph.D. (May 6, 1951- Dec 28, 2019) was a research psychologist in Psychophysiology, Rehabilitation, Cognitive Neuroscience and Data Science conducting myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) research with her husband, Mark Zinn, at their nonprofit, the Neurocognitive Research Institute. Dr Zinn's research interests included the study of brain dysfunction in chronic disease, such as myalgic encephalomyelitis (M.E.). Marcie and her husband, Mark Zinn, also founded the NeuroCognitive Research Institute. Marcie Zinn passed away suddenly from sudden heart failure[1] while working to establish the NeuroCognitive Research Institute.[2]

Dr Zinn's early research and career interests were in Performance Neuroscience and Psychology, but after being diagnosed in 2009 with herpes viral encephalitis which developed into Myalgic Encephalomyelitis, her interest turned toward using her extensive qEEG and neuroscience skills for research in M.E.. Under the leadership of Dr. Jose Montoya, she conducted a pilot study to look at cognitive dysfunction using qEEG methods. While continuing to collaborate with Jose Montoya at Stanford, she and her husband Mark published research using brain network modeling in the study of M.E. brain dysfunction.[3]

ME/CFS Common Data Element (CDE) Project[edit | edit source]

Marcie Zinn was a member of the Pain Working Group and the Neurologic/Cognitive/CNS Imaging Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control and Prevention.[4]

Advocacy[edit | edit source]

Notable studies[edit | edit source]

  • June, 2004: Development of a Self-Report Inventory to Assess Cognitive Dysfunction in Musicians. ProQuest Information and Learning Company, Ann Arbor, Michigan.
  • March, 2005: The Hippocampus in Music Learning and Performance (March, 2005). Presentation at the annual Brain Awareness Week event sponsored by Dana Alliance for Brain Initiatives, Dublin, CA.
  • Mar 2014, Cortical hypoactivation during resting eLORETA suggests central nervous system pathology in patients with chronic fatigue syndrome (Conference paper, 2014 Stanford Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Symposium: Advances in Clinical Care and Translational Research for health care providers, Stanford School of Medicine, Palo Alto, CA[7] - (Abstract - full text on request)
  • Mar 2014,  EEG peak alpha frequency is associated with chronic fatigue syndrome: a case-control observational study. Invited presentation at the 2014 Stanford Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Symposium : Advances in Clinical Care and Translational Research; March 19, 2014, Stanford University Dept. of Medicine, Palo Alto, CA.   
  • 2015, Myalgic Encephalomyelitis: Symptoms and Biomarkers[8] - (Full Text)
  • 2015,  Zinn, M.L. & Zinn, M.A. Psychophysiology for Performing Artists. In M. S. Schwartz & F. Andrasik, Eds: Biofeedback: A Practitioners Guide (4th ed.), New York: Guilford.
  • 2016, Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study[9] - (Full Text)
  • 2016, qEEG / LORETA in Assessment of Neurocognitive Impairment in a Patient with Chronic Fatigue Syndrome: A Case Report[10] - (Full Text)
  • 2016, Functional Neural Network Connectivity in Myalgic Encephalomyelitis[11] - (Full Text)
  • 2017, Small-world network analysis of cortical connectivity in Chronic Fatigue Syndrome using quantitative EEG[12] - (Full Text)
  • 2018, Cortical hypoactivation during resting EEG suggests central nervous system pathology in patients with chronic fatigue syndrome[13] - (Abstract)

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. "Dr. Marcie Zinn, Ph.D. | Kaminski Family". kaminskifamilyfuneralhomes.com. Retrieved January 10, 2020.
  2. "Click here to support Marcie Zinn Memorial Fund organized by Mark Zinn, Ph.D." gofundme.com. Retrieved January 9, 2020.
  3. Murphy, Dylan (Autumn 2021). "Meet the Scientist: Central Autonomic Network Disturbance in people with ME/CFS | A conversation with Dr. Mark Zinn" (PDF). MEE Medical. ME Association. pp. 12–13.
  4. "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved October 11, 2019.
  5. "An open letter to The Lancet, again". Virology blog. Retrieved December 3, 2019.
  6. "Trial By Error: An Open Letter to The Lancet, Two Years On". Virology blog. Retrieved December 3, 2019.
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