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Malaise
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'''Malaise''' is a feeling of being unwell, having general discomfort, uneasiness in one's bodily health or having pain, overall weakness, and is often the first indication of an [[infection]] or the onset of an illness or disease.<ref>{{Cite news | url=https://www.healthgrades.com/symptoms/malaise | title = Malaise - Symptoms, Causes, Treatments | date = 2014-06-26|access-date=2018-10-12|language=en}}</ref><ref>{{Cite journal | title = malaise|url=https://medical-dictionary.thefreedictionary.com/malaise|journal=The Free Dictionary}}</ref><ref name=":0">{{Cite web|url=https://www.healthline.com/symptom/malaise | title = Malaise: Causes, Symptoms and Diagnosis | website = healthline.com|language=en|access-date=2018-10-12}}</ref><ref>{{Cite web|url=https://www.healthhype.com/malaise-sick-feeling-meaning-causes-and-symptoms.html | title = Malaise (Sick Feeling) Meaning, Causes and Symptoms {{!}} Healthhype.com|last = Dr. Chris | first = | date = | website = healthhype.com|language=en-US|archive-url=|archive-date=|url-status=|access-date=2018-10-12}}</ref> [[ME/CFS]] patients have an almost continuous feeling of malaise and this and other symptoms can worsen upon [[exertion]] leading to [[post-exertional malaise]] (PEM), the hallmark symptom of ME/CFS. ==Malaise in ME/CFS == Malaise is a general feeling of being unwell which can be almost constant if not constant in ME/CFS depending upon the patient's disease severity. There are many symptoms experienced by patients often associated with malaise, each waxing and waning and with differing severity. These malaise and other ME/CFS disease symptoms will worsen and increase in number upon exertion due to PEM.<ref>{{Cite journal | last = Jason | first = Leonard A. | last2 = Evans | first2 = Meredyth | last3 = So | first3 = Suzanna | last4 = Scott | first4 = Jilian | last5 = Brown | first5 = Abigail | date = 2015-01-02 | title = Problems in Defining Post-Exertional Malaise|url=http://www.tandfonline.com/doi/abs/10.1080/10852352.2014.973239|journal=Journal of Prevention & Intervention in the Community|language=en|volume=43|issue=1|pages=20β31|doi=10.1080/10852352.2014.973239|issn=1085-2352|pmc = 4295644|pmid=25584525}}</ref> == Cause == There are many possible causes of malaise. A cold, [[influenza]], and [[Influenza A virus subtype H1N1|swine flu]]; hypoglycemia common in [[diabetes]]; [[Streptococcus|strep throat]]; [[Sinusitis|sinus infections]]; [[bronchitis]]; [[hepatitis]]; [[Varicella zoster virus|shingles]]; [[malaria]]; [[Systemic lupus erythematosus|lupus]]; obstructive uropathy; [[HIV]]/[[AIDS]]; dengue hemorrhagic fever; [[ebola]]; [[chronic fatigue syndrome]]; neutropenia (low white blood cells); necrotizing fasciitis (soft tissue inflammation); [[lyme disease]]; [[encephalitis]]; chronic kidney diseas; pyelonephritis; [[non-Hodgkin's lymphoma]]; infectious [[mononucleosis]]; bone infection; [[chickenpox]]; walking pneumonia (atypical pneumonia); and cellulitis, to name just a few.<ref name=":0" /> == Symptoms == Depending on the underlying cause, different symptoms can occur. '''Physical symptoms''' '''affecting the body''' * [[Abdominal pain]] or cramping * Enlarged [[Lymph node|lymph nodes]] * [[Fever]] and chills * [[Flu-like symptoms]] ([[fatigue]], [[fever]], [[sore throat]], [[headache]], [[cough]], aches, and pain<nowiki/>s) * [[Arthralgia|Joint pains]] * Missed or irregular [[Menstrual cycle|menstrual periods]] * [[Myalgia|Muscle aches]] * Severe fatigue * Unexplained weight loss<ref name=":1">{{Cite news | url=https://www.healthgrades.com/right-care/mental-health-and-behavior/malaise--symptoms | title = Malaise - Symptoms, Causes, Treatments|last = | first = | date = 2014-06-26|work=Health Grades|access-date=2018-10-12|archive-url=|archive-date=|url-status= | page = 2|at=|language=en|quote=}}</ref> '''Other symptoms that may occur along with malaise''' '''such as those related to emotional or psychological disturbance''' * [[Anxiety]] * Changes in [[Mood swings|mood]], [[Personality change|personality]] or [[Behavior change|behavior]] * [[Depression]] * Difficulty with [[Memory problems|memory]], [[Cognitive dysfunction|thinking]], [[Dysphasia|talking]], comprehension, writing or reading * Fatigue * [[Excessive irritability|Irritability]] and mood changes * Lack of energy * [[Lethargy]]<ref name=":1" /> '''Serious symptoms that might indicate a life-threatening condition''' * [[Chest pain]] or pressure * Difficulty breathing * High fever (higher than 101 degrees Fahrenheit) * Inability to eat or drink * [[Paralysis]] * Severe abdominal pain or cramping<ref name=":1" /> == See also == * [[Post-exertional malaise]] == Learn more == == References == {{Reflist}} [[Category:Signs and symptoms]] [[Category:Immune signs and symptoms]]
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