m6A
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
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N6-methyladenosine or m6A is the N6 position of adenosine is vital for many different biological processes including transcription, translation and decay of mRNA.[1]
Function[edit | edit source]
Widespread mRNA methylation known as N6-adenosine methylation occurs at m6A, and it is believed to apply to all RNA viruses infections and some DNA viruses.[2]
In humans and other mammals m6A-related methyltransferases are mostly made up of a complex of methyltransferase-like protein 3 (METTL3) and methyltransferase-like protein 14 (METTL14).[1]
ME/CFS[edit | edit source]
Notable studies[edit | edit source]
- 2021, COVID-19: A methyl-group assault?[1] (Full text)
