List of myalgic encephalomyelitis and chronic fatigue syndrome outbreaks: Difference between revisions

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{{Cleanup | reason=outbreak years/names need reformatting (the first pass isn't really that great!), outbreaks should also be sorted by region, hyperlinks should be added to major outbreaks that may eventually have their own pages | date=November 2015}}
There have been dozens of documented outbreaks of [[ME]] and [[CFS]] since the 1930s. Many of these outbreaks occurred at institutions for example, hospitals, schools, army bases or convents. The true number of clusters and outbreaks is likely vastly higher.  
There have been dozens of documented outbreaks of [[ME]] and [[CFS]] since the 1930s. Many of these outbreaks occurred at institutions for example, hospitals, schools, army bases or convents. The true number of clusters and outbreaks is likely vastly higher.  


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==== [[1937 Erstfeld outbreak|1937 - Erstfeld, Switzerland]] ====
==== [[1937 Erstfeld outbreak|1937 - Erstfeld, Switzerland]] ====
Outbreak described as "Abortive Poliomyelitis."
In less than two weeks, 130 soldiers stationed in Erstfeld, Switzerland became ill with a disease that was attributed to "Abortive Poliomyelitis."<ref name="Parish, 1978"/>


==== [[1937 St. Gallen outbreak|1937 - St. Gallen, Switzerland]] ====
==== [[1937 St. Gallen outbreak|1937 - St. Gallen, Switzerland]] ====
Outbreak in Frohburg Hospital described as "Abortive Poliomyelitis."
Outbreak in the women's section of a hospital in St Gallen, Switzerland affecting 28 staff and patients. They were diagnosed with "Abortive Poliomyelitis."
<ref name="Parish, 1978"/>


==== [[1939 Middlesex outbreak|1939 - Middlesex, England]] ====
==== [[1939 Middlesex outbreak|1939 - Middlesex, England]] ====
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==== [[1939 Degersheim outbreak|1939 - Degersheim, St. Gallen, Switzerland]] ====
==== [[1939 Degersheim outbreak|1939 - Degersheim, St. Gallen, Switzerland]] ====
Outbreak described as "Abortive Poliomyelitis."
Seventy-three cases of epidemic neuromyasthenia were reported among 800 soldiers stationed in Degersheim, Switzerland.<ref name="Parish, 1978"/>


=== 1940s ===
=== 1940s ===
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Epidemic described as "pleurodynia with prominent neurological symptoms and no demonstrable cause."
Epidemic described as "pleurodynia with prominent neurological symptoms and no demonstrable cause."


==== [[1946 Iceland outbreak|1946-47 - Iceland]] ====
==== [[1946-47 Iceland outbreak|1946-47 - Iceland]] ====
"Mixed epidemics of poliomyelitis and a disease resembling poliomyelitis with the character of the Akureyri Disease."
"Mixed epidemics of poliomyelitis and a disease resembling poliomyelitis with the character of the Akureyri Disease."


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"A disease epidemic in Iceland simulating Poliomyelitis" in three separate towns during this time.
"A disease epidemic in Iceland simulating Poliomyelitis" in three separate towns during this time.


==== [[1949 Adelaide outbreak|1949-1953 - Adelaide, Australia]] ====
==== [[1949-53 Adelaide outbreak|1949-1953 - Adelaide, Australia]] ====
Outbreak of a disease resembling poliomyelitis, during/after a poliomyelitis epidemic.
Outbreak of a disease resembling poliomyelitis, during/after a poliomyelitis epidemic.
: 1951-06-30: "The author describes a disease which has been epidemic in Adelaide since August 1949, and which closely resembles poliomyelitis. Its most characteristic feature is the absence of abnormal findings in the cerebrospinal fluid. Thus, out of 1,350 consecutive cases of " poliomyelitis ", 800 had less than 10 cells per cubic millimetre in the cerebrospinal fluid (the majority had less than 5 cells); and the protein values were normal in all but 2 of these cases. 
: The onset of this illness was either gradual or sudden and, if sudden, headache was a constant feature and often of marked intensity. Muscle weakness - generally slight and diffuse in distribution - occurred more commonly in the legs than in the arms. Where paralysis was severe, rapid recovery generally ensued. Two noteworthy features of the muscle involvement in this disease were as follows: the pain frequently persisted in various muscles for periods up to six months after the acute illness; in some cases the onset of muscle weakness was delayed for several months. The ultimate prognosis was always good, but frequent recurrences were not uncommon. The greatest disabling feature of the disease lay in the psychological sequelae which were fairly constant and comprised one or more of the following - lack of concentration, depression, irritability, emotional instability and hyperacuity of hearing. These manifestations, however, eventually resolved completely".<ref> Dr R.A. Pellew, [http://www.cabdirect.org/abstracts/19522700678.html;jsessionid=AA4534CA199AC800732B3877608F5CE0 "A Clinical Description of a Disease resembling Poliomyelitis, seen in Adelaide, 1949-1951"] ''Medical Journal of Australia'', Medical Journal of Australia 1951, June 30 Vol. 1 No. 26 pp. 944-6</ref>
: 1952-02-01: "Dr. R.A. Pellew, of Adelaide, who will also address the conference, believes that most of SA's 3,130 polio cases during the past two years and nine months have suffered a mild form of the disease."<ref> [http://trove.nla.gov.au/newspaper/article/47377426? "Conference on Polio"] "The Advertiser'', Adelaide Australia, 01 February 1952</ref>
: 1955: The Adelaide outbreak of atypical polio was associated with a reduction in typical polio cases. "There was ... a marked regression of [typical] poliomyelitis in South Australia (413 notifications as compared with 721)." (from page 645 of 1955 WHO report <ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542300/ "Poliomyelitis in 1953"] ''Bull World Health Organ.'' 1955;12(4):595-649.</ref>)


===1950s===
===1950s===
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Famous outbreak of benign myalgic encephalomyelitis among [[Royal Free Hospital]] staff.
Famous outbreak of benign myalgic encephalomyelitis among [[Royal Free Hospital]] staff.


==== [[1955 Perth AUS outbreak|1955 - Perth, Australia]] ====
==== [[1955 Perth outbreak|1955 - Perth, Australia]] ====
"Virus epidemic in recurrent waves."
"Virus epidemic in recurrent waves."


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Reports of sporadic cases of influenza-like illness.
Reports of sporadic cases of influenza-like illness.


==== [[1959 England|1959 - England]] ====
==== [[1959 England outbreak|1959 - England]] ====
Article describing sporadic cases and "The psychiatric sequelae of Benign Myalgic Encephalomyelitis."
Article describing sporadic cases and "The psychiatric sequelae of Benign Myalgic Encephalomyelitis."


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==== [[1964 London NW outbreak|1964-66 - N.W. London, England]] ====
==== [[1964 London NW outbreak|1964-66 - N.W. London, England]] ====
Outbreak described as epidemic malaise and epidemic neuromyasthenia.
Outbreak described as epidemic malaise and epidemic neuromyasthenia occurred in North Finchley, a suburb of London, England.


==== [[1964 Franklin outbreak|1964-66 - Franklin, Kentucky, USA]] ====
==== [[1964 Franklin outbreak|1964-66 - Franklin, Kentucky, USA]] ====
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==== [[1975 Sacramento outbreak|1975 - Sacramento, California, USA]] ====
==== [[1975 Sacramento outbreak|1975 - Sacramento, California, USA]] ====
"200 hospital staff in the [Mercy San Juan Hospital] fell ill in August September 1975. The epidemic appears to have spread to the children of the hospital staff and from there to the children's teachers.  43 have been seriously disabled with chronic illness from 1975-1992" [at publication of this text]<ref>need more info</ref>.
In 1975, an epidemic started first among the ICU staff and later spread throughout Mercy San Juan Hospital, in Carmichael, a suburb of Sacramento, CA. An estimated 200 people became ill. Dr Ryll, who headed the investigating medical team, called it "Infectious Venulitis" which he later believed to be a variant of [[ME/CFS]].<ref>http://www.ncf-net.org/forum/InfVenulitis-Fall05.htm</ref><ref>http://www.oocities.org/sezar99q/MECFSInfectiousVenulitis.html</ref>


==== [[1976 Ireland SW outbreak|1976 - Southwest Ireland]] ====
==== [[1976 Ireland SW outbreak|1976 - Southwest Ireland]] ====
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==== [[1978 notes|1978 - Symposium]] ====
==== [[1978 notes|1978 - Symposium]] ====
[Ed. note: Dr. Hyde's text notes that the first major ME symposium was held at the Royal Society of Medicine in London in this year.  ME aka epidemic neuromyasthenia, viral relationships to this disease, biochemical abnormalities in patients and other subjects were discussed by experts such as Shelokov, Ramsay, Richardson, Behan, Parish and others.<ref>to be moved</ref>
Ed. note: Dr. Hyde's text notes that the first major ME symposium was held at the Royal Society of Medicine in London in this year.  ME aka epidemic neuromyasthenia, viral relationships to this disease, biochemical abnormalities in patients and other subjects were discussed by experts such as Shelokov, Ramsay, Richardson, Behan, Parish and others.<ref>to be moved</ref>


==== [[1979 Southampton outbreak| 1979 - Southampton, England]] ====
==== [[1979 Southampton outbreak| 1979 - Southampton, England]] ====
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===1980s===
===1980s===
1980-1988 Children’s hospital San Diego outbreak closes down Hospital. CDC investigates. Six children die 1980.  Medical doctor and two intensive care nurses die.


==== [[Ayrshire|1980-81 - West Kilbridge, Ayrshire, Scotland]] ====
==== [[Ayrshire|1980-81 - West Kilbridge, Ayrshire, Scotland]] ====
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Outbreak first described and an "unexplained illness," later as M.E.  Included here are outbreaks in Dunedin and Hamilton New Zealand.
Outbreak first described and an "unexplained illness," later as M.E.  Included here are outbreaks in Dunedin and Hamilton New Zealand.


==== [[1984 USA endemic|1984 - North America (Endemic)]] ====
==== [[1984 North America endemic|1984 - North America (Endemic)]] ====
"From 1984 until 1992 [at publication of this text] an endemic period occurred in which an usually large number of cluster and epidemics of M.E./CFS have been recognized in North America.  After an apparent initial increase in the morbidity in 1983 there seemed to have appeared in late summer of 1984 an unprecedented increase of sporadic and epidemic cases across North America.  Although certain geographical hot spots seen to have taken up much of the medical interest, this endemic situation probably represents an unusual and unremitting morbidity in all areas of the United States and Canada." -Dr. Byron Hyde-
"From 1984 until 1992 [at publication of this text] an endemic period occurred in which an usually large number of cluster and epidemics of M.E./CFS have been recognized in North America.  After an apparent initial increase in the morbidity in 1983 there seemed to have appeared in late summer of 1984 an unprecedented increase of sporadic and epidemic cases across North America.  Although certain geographical hot spots seen to have taken up much of the medical interest, this endemic situation probably represents an unusual and unremitting morbidity in all areas of the United States and Canada." -Dr. Byron Hyde-


====[[1984 Incline Village chronic fatigue syndrome outbreak|1984 - Incline village, Lake Tahoe, Nevada, USA]] ====
====[[1984 Incline Village chronic fatigue syndrome outbreak|1984 - Incline village, Lake Tahoe, Nevada, USA]] ====
A chronic illness characterized by fatigue, neurologic and immunologic disorders and active human herpesvirus type 6 infection. This community epidemic, apparently started in a girls' basketball team, then involved primarily teacher in at least three high schools, and then large numbers of the community.<ref name="NewsWeek19901111"/>
A chronic illness characterized by fatigue, neurologic and immunologic disorders and active human herpesvirus type 6 infection. This community epidemic apparently started in a girls' basketball team, then involved primarily teachers in at least three high schools, and then large numbers of the community.<ref name="Newsweek19901111"/>
 
Note: This outbreak prompted a [[Centers for Disease Control]] response and was the catalyst for the name [[Chronic fatigue syndrome]] and the development of the CDC's 1994 research diagnostic tool [[Fukuda criteria]] used worldwide.


==== [[1984 Chapel Hill outbreak|1984 - Chapel Hill, North Carolina, USA]] ====
==== [[1984 Chapel Hill outbreak|1984 - Chapel Hill, North Carolina, USA]] ====
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All the members of the N.C. Symphony Orchestra, Chapel Hill, NC got sick. Seven remained ill with chronic fatigue as late as 2009.
All the members of the N.C. Symphony Orchestra, Chapel Hill, NC got sick. Seven remained ill with chronic fatigue as late as 2009.
   
   
A series of studies done in 1988 and 1989 by the University of Pittsburgh Cancer Center showed that four the inflicted NC orchestra members who developed cancer had lower levels of activity of natural killer cells, a type of immune cell that can directly kill cancer.
A series of studies done in 1988 and 1989 by the University of Pittsburgh Cancer Center showed that four of the inflicted NC orchestra members who developed cancer had lower levels of activity of natural killer cells, a type of immune cell that can directly kill cancer.


==== [[1984 Montreal outbreak| 1984 - Montreal, Quebec-Ontario, Canada]] ====
==== [[1984 Montreal outbreak| 1984 - Montreal, Quebec-Ontario, Canada]] ====
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==== [[1984 Truckee outbreak|1984-85 - Truckee, California, USA]] ====
==== [[1984 Truckee outbreak|1984-85 - Truckee, California, USA]] ====
M.E. epidemic involving teachers and students.
M.E. epidemic involving teachers and students.
1984 - 1985: Incline Village Nevada Lake Tahoe outbreak in town and all people vacationing at
This resort town.


==== [[1985 Lyndonville outbreak|1985 - Lyndonville, New York, USA]] ====
==== [[1985 Lyndonville outbreak|1985 - Lyndonville, New York, USA]] ====
M.E. epidemic in a rural community involving children and adults.<ref name="NewsWeek19901111"/>
M.E. epidemic in a rural community involving children and adults.<ref name="Newsweek19901111"/>


==== [[1985 Yerington outbreak|1985 Yerington, Nevada, USA]] ====
==== [[1985 Yerington outbreak|1985 Yerington, Nevada, USA]] ====
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==== [[1990 Elk Grove CA outbreak|1990 - Elk Grove, California, USA]] ====
==== [[1990 Elk Grove CA outbreak|1990 - Elk Grove, California, USA]] ====
M.E. epidemic among teachers and students.
M.E. epidemic among teachers and students.
==== [[1996 Mohave Valley region, Arizona | 1996 - Mohave Valley region, Arizona, USA]] ====
Over 100 people became ill with a "multi-system stealth virus infection with encephalopathy (MSVIE)."
A protracted course followed, with a diverse range of symptoms similar to CFS.<ref>http://www.ccid.org/stealth/publications/msv.htm</ref>


==Outbreaks by region==
==Outbreaks by region==


===North America===
===North America===
*[[1984 North America endemic|1984 - North America (Endemic)]]
====Canada====
*[[1984 Montreal outbreak| 1984 - Montreal, Quebec-Ontario, Canada]]
====United States====
*[[Los Angeles atypical polio outbreak|1934 - Los Angeles, USA]]
*[[1936 Fond-du-Lac outbreak|1936 - Fond-du-Lac, Wisconsin, USA]]
*[[1945 Pennsylvania outbreak|1945 - University Hospital of Pennsylvania, USA]]
*[[1950 Louisville outbreak|1950 - Louisville, Kentucky, USA]]
*[[1950 Upper New York State outbreak|1950 - Upper New York State, USA]]
*[[1952 Florida outbreak|1952 - Lakeland, Florida, USA]]
*[[1953 Maryland outbreak|1953 - Rockville, Maryland, USA]]
*[[1954 Florida outbreak|1954 - Tallahassee, Florida, USA]]
*[[1954 Seward outbreak|1954 - Seward, Alaska]]
*[[1956 Ridgefield outbreak|1956 - Ridgefield, Connecticut, USA]]
*[[1956 Punta Gorda outbreak|1956 - Punta Gorda, Florida, USA]]
*[[1956 Massachusetts outbreak|1956 - Pittsfield, Williamstown, Massachusetts, USA]]
*[[1961 New York State outbreak| 1961-62 - New York State, USA]]
*[[1964 Franklin outbreak|1964-66 - Franklin, Kentucky, USA]]
*[[1965 Galveston outbreak|1965-66 - Galveston County, Texas, USA]]
*[[1969 New York outbreak|1969 - State University of New York, USA]]
*[[1970 Lackland outbreak| 1970 - Lackland Air Force Base, Texas, USA]]
*[[1975 Sacramento outbreak|1975 - Sacramento, California, USA]]
*[[1977 Dallas outbreak|1977 - Dallas-Fort Worth, Texas, USA]]
*[[1984 Incline Village chronic fatigue syndrome outbreak|1984 - Incline village, Lake Tahoe, Nevada, USA]]
*[[1984 Chapel Hill outbreak|1984 - Chapel Hill, North Carolina, USA]]
*[[1984 Truckee outbreak|1984-85 - Truckee, California, USA]]
*[[1985 Lyndonville outbreak|1985 - Lyndonville, New York, USA]]
*[[1985 Yerington outbreak|1985 Yerington, Nevada, USA]]
*[[1986 Placerville outbreak|1986 - Placerville, California, USA]]
*[[1988 Sonora CA outbreak|1988 - Sonora, California, USA]]
*[[1989 Roseville CA outbreak|1989 - Roseville, California, USA]]
*[[1990 Elk Grove CA outbreak|1990 - Elk Grove, California, USA]]
*[[1996 Mohave Valley region, AZ outbreak | 1996 - Mohave Valley region, Arizona, USA]]


===Europe===
===Europe===
====Denmark====
*[[1952 Copenhagen outbreak| 1952 - Copenhagen, Denmark]]
*[[1953 Jutland outbreak|1953 - Jutland, Denmark]]
====Germany====
*[[1954 Berlin outbreak|1954 - Berlin, Germany]]
====Greece====
*[[1958 Athens outbreak|1958 - Athens, Greece]]
====Iceland====
*[[1946-47 Iceland outbreak|1946-47 - Iceland]]
*[[Akureyri_outbreak|1948-49 - North Coast Towns, Iceland]]
*[[1955 Iceland outbreak|1955-56 - Patreksfordur and Thorshofn, Iceland]]
====Ireland====
*[[1976 Ireland SW outbreak|1976 - Southwest Ireland]]
====Switzerland====
*[[1937 Erstfeld outbreak|1937 - Erstfeld, Switzerland]]
*[[1937 St. Gallen outbreak|1937 - St. Gallen, Switzerland]]
*[[1939 Degersheim outbreak|1939 - Degersheim, St. Gallen, Switzerland]]
*[[1961 Basel outbreak|1961 - Basel, Switzerland]]
====United Kingdom====
*[[1939 Middlesex outbreak|1939 - Middlesex, England]]
*[[1952 London outbreak|1952 - London, England]]
*[[1953 Coventry outbreak|1953 - Coventry and Coventry District, England]]
*[[1954 Liverpool outbreak|1954 - Liverpool, England]]
*[[Dalston|1954 - Dalston, Cumbria, England]]
*[[Royal Free Hospital outbreak|1955 - London, England]]
*[[1955 Wales outbreak|1955 - Gilfach Goch, Wales]]
*[[1955 London outbreak|1955-56 - North West London, England]]
*[[1956 Lancashire outbreak|1956 - Newton-le-Willows, Lancashire, England]]
*[[1956 Coventry outbreak|1956-57 - Coventry, England]]
*[[1958 London SW outbreak|1958-59 - S.W. London, England]]
*[[1959 Newcastle outbreak|1959 - Newcastle upon Tyne, England]]
*[[1959 London NW outbreak|1959 - N.W. London, England]]
*[[1959 England|1959 - England]]
*[[1964 London NW outbreak|1964-66 - N.W. London, England]]
*[[1967 Edinburgh outbreak|1967-70 - Edinburgh, Scotland]]
*[[1970 London outbreak|1970-71 - London, England]]
*[[1979 Southampton outbreak| 1979 - Southampton, England]]
*[[Ayrshire|1980-81 - West Kilbridge, Ayrshire, Scotland]]
*[[1980 Helensburgh outbreak|1980-83 - Helensburgh, Scotland]]
*[[1981 Stirlingshire outbreak|1981-82 - Stirlingshire, Scotland]]
===Asia===
====Lebanon====
*[[1968 Fraidek outbreak|1968 - Fraidek, Lebanon]]


===Africa===
===Africa===


=== Australia and New Zealand ===
====Sierra Leone====
*[[1955 Segbwema outbreak|1955-56 - Segbwema, Sierra Leone]]
 
====South Africa====
*[[1955 Durban outbreak|1955 - Durban and Durban City, South Africa]]
 
===Australia and New Zealand===
 
====Australia====
 
*[[1949-53 Adelaide outbreak|1949-1953 - Adelaide, Australia]]
*[[1955 Perth outbreak|1955 - Perth, Australia]]
*[[1957 South Australia outbreak|1957 - Brighton, South Australia]]
*[[1981 Gunnedah outbreak|1981 - Gunnedah, NSW, Australia]]
*[[1988 Narrabeen outbreak|1988 - Narrabeen, NSW, Australia]]
 
====New Zealand====


*[[#1949_Adelaide_outbreak|1949-54 - Adelaide, South Australia]]
*[[#1955_Perth_AUS_outbreak|1955 - Perth, Western Australia]]
*[[#1957_South_Australia_outbreak|1957 - Brighton, South Australia]]
*[[Tapanui Flu|1984 - West Otago, New Zealand]]
*[[Tapanui Flu|1984 - West Otago, New Zealand]]
*[[#1988_Narrabeen_outbreak|1988 - Narrabeen, NSW, Australia]]


== Related Lists ==
== Related Lists ==
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* [http://www.meresearch.org.uk/wp-content/uploads/2012/11/ME-Research-UK-Research-Publications-on-ME-epidemics-1934-1980.pdf Reference index of papers published on epidemics of ME 1934-80 (collected by Dr J. Gordon Parish)], ME Research UK, 1980.
* [http://www.meresearch.org.uk/wp-content/uploads/2012/11/ME-Research-UK-Research-Publications-on-ME-epidemics-1934-1980.pdf Reference index of papers published on epidemics of ME 1934-80 (collected by Dr J. Gordon Parish)], ME Research UK, 1980.
* [http://www.nightingale.ca/index.php?target=bookoffer The Clinical and Scientific Basis of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome (edited by Dr. Byron Hyde)], Nightingale Foundation, 1992.
* [http://www.nightingale.ca/index.php?target=bookoffer The Clinical and Scientific Basis of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome (edited by Dr. Byron Hyde)], Nightingale Foundation, 1992.
== See also ==
*[[Definitions of ME and CFS]]


==References==
==References==
<references>
<references>
<ref name="Parish, 1978">
{{Citation
| last1  = Parish            | first1 = J.G.              | authorlink1 = Gordon Parish
| title  = Early outbreaks of 'epidemic neuromyasthenia'.
| journal = Postgraduate Medical Journal    | volume = 54  | issue = 637  | page = 711-717
| date    = November 1978
| pmid    = 370810
| url    = http://www.ncbi.nlm.nih.gov/pubmed/370810
}}
</ref>


<ref name="NewsWeek19901111">{{citation
<ref name="Newsweek19901111">{{citation
| title  = Chronic Fatigue Syndrome
| title  = Chronic Fatigue Syndrome
| journal = NewsWeek
| journal = Newsweek
| date    = 1990-11-11
| date    = 1990-11-11
| url    = http://www.newsweek.com/chronic-fatigue-syndrome-205712
| url    = http://www.newsweek.com/chronic-fatigue-syndrome-205712
}}</ref>
}}</ref>
</references>
[[Category:Outbreaks]]
[[Category:History]]

Revision as of 17:06, May 21, 2018

There have been dozens of documented outbreaks of ME and CFS since the 1930s. Many of these outbreaks occurred at institutions for example, hospitals, schools, army bases or convents. The true number of clusters and outbreaks is likely vastly higher.

History of the name[edit | edit source]

Before the polio vaccine, outbreaks were often observed in towns experiencing polio epidemics, hence one of ME's earliest names, atypical polio. It is not known whether there is a relationship between polio outbreaks and ME or if outbreaks of ME were more likely to be reported when public health authorities were already mobilized for an earlier crisis.

After the outbreak in Akureyri, Iceland in 1946, the disease came to be called "Akureyri Disease" or Icelandic disease through much of the 1940s and 1950s. It was named Myalgic Encephalomyelitis after London's Royal Free Hospital outbreak in 1955.

After the Incline Village outbreak in Nevada in 1984, the disease came to be called and redefined as Chronic Fatigue Syndrome.

Outbreaks by decade[edit | edit source]

1930s[edit | edit source]

1934 - Los Angeles, USA[edit | edit source]

Epidemic among personnel at L.A. County Hospital, Ruth Protection Home and throughout California, paralleling poliomyelitis, often diagnosed as atypical poliomyelitis, sometimes including arthropathy.

1936 - Fond-du-Lac, Wisconsin, USA[edit | edit source]

An outbreak of "encephalitis" in St. Agnes Convent.

1937 - Erstfeld, Switzerland[edit | edit source]

In less than two weeks, 130 soldiers stationed in Erstfeld, Switzerland became ill with a disease that was attributed to "Abortive Poliomyelitis."[1]

1937 - St. Gallen, Switzerland[edit | edit source]

Outbreak in the women's section of a hospital in St Gallen, Switzerland affecting 28 staff and patients. They were diagnosed with "Abortive Poliomyelitis." [1]

1939 - Middlesex, England[edit | edit source]

Outbreak at Harefield Sanatorium - "Persistent myalgia following sore throat."

1939 - Degersheim, St. Gallen, Switzerland[edit | edit source]

Seventy-three cases of epidemic neuromyasthenia were reported among 800 soldiers stationed in Degersheim, Switzerland.[1]

1940s[edit | edit source]

1945 - University Hospital of Pennsylvania, USA[edit | edit source]

Epidemic described as "pleurodynia with prominent neurological symptoms and no demonstrable cause."

1946-47 - Iceland[edit | edit source]

"Mixed epidemics of poliomyelitis and a disease resembling poliomyelitis with the character of the Akureyri Disease."

1948-49 - North Coast Towns, Iceland[edit | edit source]

"A disease epidemic in Iceland simulating Poliomyelitis" in three separate towns during this time.

1949-1953 - Adelaide, Australia[edit | edit source]

Outbreak of a disease resembling poliomyelitis, during/after a poliomyelitis epidemic.

1950s[edit | edit source]

1950 - Louisville, Kentucky, USA[edit | edit source]

Outbreak in the Nurse's Training School of St. Joseph Infirmary, later described as "epidemic neuromyasthenia."

1950 - Upper New York State, USA[edit | edit source]

Outbreak described as resembling the "Iceland Disease...simulating Acute Anterior Poliomyelitis."

1952 - London, England[edit | edit source]

Outbreak at Middlesex Hospital Nurses' Home described as "Encephalomyelitis associated with Poliomyelitis Virus."

1952 - Copenhagen, Denmark[edit | edit source]

Outbreak described as "epidemic myositis."

1952 - Lakeland, Florida, USA[edit | edit source]

Outbreak described as epidemic neuromyasthenia.

1953 - Coventry and Coventry District, England[edit | edit source]

"An illness resembling Poliomyelitis observed in nurses."

1953 - Rockville, Maryland, USA[edit | edit source]

Chestnut Lodge Hospital student nurses described with poliomyelitis-like epidemic neuromyasthenia.

1953 - Jutland, Denmark[edit | edit source]

Outbreak of "Epidemic encephalitis with vertigo."

1954 - Tallahassee, Florida, USA[edit | edit source]

Bond JO. A new clinical entity? Lancet 1956; 2:256.

1954 - Seward, Alaska[edit | edit source]

Outbreak described as "Benign Myalgic Encephalomyelitis (Iceland Disease)."

1954 - Berlin, Germany[edit | edit source]

Among the British Army, a "further outbreak of a disease resembling poliomyelitis."

1954 - Liverpool, England[edit | edit source]

Outbreak among medical and nursing staff in a Liverpool Hospital.

1954 - Dalston, Cumbria, England[edit | edit source]

"...an unusual disease seen in epidemic and sporadic form in general practice in 1955 and subsequent years."

1955 - London, England[edit | edit source]

Famous outbreak of benign myalgic encephalomyelitis among Royal Free Hospital staff.

1955 - Perth, Australia[edit | edit source]

"Virus epidemic in recurrent waves."

1955 - Gilfach Goch, Wales[edit | edit source]

Outbreak of Benign encephalomyelitis.

1955 - Durban and Durban City, South Africa[edit | edit source]

Outbreak among nurses at Addington Hospital called "The Durban Mystery Disease" describing neuromuscular dysfunction, and epidemic myalgic encephalomyelopathy, including sporadic cases in Johannesburg of a outbreak resembling poliomyelitis.

1955-56 - Segbwema, Sierra Leone[edit | edit source]

An outbreak of encephalomyelitis.

1955-56 - Patreksfordur and Thorshofn, Iceland[edit | edit source]

Unusual response to poliomyelitis vaccination.

1955-56 - North West London, England[edit | edit source]

Outbreak of acute infective encephalomyelitis simulating poliomyelitis among a residential home for nurses.

1956 - Ridgefield, Connecticut, USA[edit | edit source]

An epidemic of neuromyasthenia.

1956 - Punta Gorda, Florida, USA[edit | edit source]

An outbreak of epidemic neuromyasthenia.

1956 - Newton-le-Willows, Lancashire, England[edit | edit source]

Outbreak described as "lymphocytic meningo-encephalitis with myalgia and rash," "An outbreak of a disease believed to have been cause by Echo 9 virus," with other varying descriptions.

1956 - Pittsfield, Williamstown, Massachusetts, USA[edit | edit source]

Outbreak of "epidemic neuromyasthenia" later described as benign myalgic encephalomyelitis. (Included in this summary are sporadic cases in Hygiea, Sweden, with descriptions of encephalitis, meningitis or poliomyelitis; Coxsackie B and Echo Virus infections; benign myalgic encephalomyelitis.)

1956-57 - Coventry, England[edit | edit source]

Outbreak described as epidemic malaise and benign myalgic encephalomyelitis.

1957 - Brighton, South Australia[edit | edit source]

Outbreak described as "Coxsackie, Echo Virus meningitis and myalgic encephalomyelitis", "Epidemic myalgic encephalomyelitis," and "Benign myalgic encephalomyelitis."

1958 - Athens, Greece[edit | edit source]

An outbreak of benign myalgic encephalomyelitis in a nurse's school, "periostitis and arthropathy noted." (Included in this summary is an outbreak of benign myalgic encephalomyelitis in Switzerland.)

1958-59 - S.W. London, England[edit | edit source]

Reports of sporadic cases of myalgic encephalomyelitis.

1959 - Newcastle upon Tyne, England[edit | edit source]

Outbreak of benign myalgic encephalomylitis.

1959 - N.W. London, England[edit | edit source]

Reports of sporadic cases of influenza-like illness.

1959 - England[edit | edit source]

Article describing sporadic cases and "The psychiatric sequelae of Benign Myalgic Encephalomyelitis."

1960s[edit | edit source]

1961 - Basel, Switzerland[edit | edit source]

Sporadic case of benign myalgic encephalomyelitis described.

1961-62 - New York State, USA[edit | edit source]

Outbreak described as epidemic neuromyasthenia in a convent in New York State.

1964-66 - N.W. London, England[edit | edit source]

Outbreak described as epidemic malaise and epidemic neuromyasthenia occurred in North Finchley, a suburb of London, England.

1964-66 - Franklin, Kentucky, USA[edit | edit source]

Outbreak of "neurmyasthenia" in a Kentucky factory, possibly due to mercury exposure.

1965-66 - Galveston County, Texas, USA[edit | edit source]

Outbreak described as "Epidemic Neuromyasthenia Variant?" and "Epidemic Diencephalomyelitis," the latter describing neuropsychiatric, cardiovascular and endocrine disorders.

1967-70 - Edinburgh, Scotland[edit | edit source]

Sporadic cases resembling benign myalgic encephalomyelitis.

1968 - Fraidek, Lebanon[edit | edit source]

Report on an epidemic of benign myalgic encephalomyelitis.

1969 - State University of New York, USA[edit | edit source]

Medical Centre - report of epidemic Neuromyasthenia and "unidentified symptom complex."

1970s[edit | edit source]

1970 - Lackland Air Force Base, Texas, USA[edit | edit source]

Epidemic Neuromyasthenia reported. "A syndrome or disease?"

1970-71 - London, England[edit | edit source]

An outbreak of "epidemic neuromyasthenia" among nurses a the Hospital for Sick Children, Great Oromond Street.

1975 - Sacramento, California, USA[edit | edit source]

In 1975, an epidemic started first among the ICU staff and later spread throughout Mercy San Juan Hospital, in Carmichael, a suburb of Sacramento, CA. An estimated 200 people became ill. Dr Ryll, who headed the investigating medical team, called it "Infectious Venulitis" which he later believed to be a variant of ME/CFS.[2][3]

1976 - Southwest Ireland[edit | edit source]

Reports on Mylagic Encephalomyelits and epidemic neuromyasthenia in this region.

1977 - Dallas-Fort Worth, Texas, USA[edit | edit source]

"Epidemic Neuromyasthenia" reported.

1978 - Symposium[edit | edit source]

Ed. note: Dr. Hyde's text notes that the first major ME symposium was held at the Royal Society of Medicine in London in this year. ME aka epidemic neuromyasthenia, viral relationships to this disease, biochemical abnormalities in patients and other subjects were discussed by experts such as Shelokov, Ramsay, Richardson, Behan, Parish and others.[4]

1979 - Southampton, England[edit | edit source]

Outbreak of M.E. in a girls' school.

1980s[edit | edit source]

1980-1988 Children’s hospital San Diego outbreak closes down Hospital. CDC investigates. Six children die 1980. Medical doctor and two intensive care nurses die.

1980-81 - West Kilbridge, Ayrshire, Scotland[edit | edit source]

M.E. epidemic reported in a rural medical practice.

1980-83 - Helensburgh, Scotland[edit | edit source]

Coxsackie B outbreak reported in a general practice.

1981-82 - Stirlingshire, Scotland[edit | edit source]

Sporadic cases of M.E. reported.

1981 - Gunnedah, NSW, Australia[edit | edit source]

The Gunnedah outbreak was linked with pesticides, which were conjectured to be interacting with viruses and other environmental chemicals in a post-viral syndrome.[5] Those affected included one local GP, with that GP forming the view this was clearly a physical illness. The outbreak was featured in a film More than Just Poison made in 1986 by the Toxic and Hazardous Chemicals Committee.[6]

1984 - Tapanui & West Otago, New Zealand[edit | edit source]

Outbreak first described and an "unexplained illness," later as M.E. Included here are outbreaks in Dunedin and Hamilton New Zealand.

1984 - North America (Endemic)[edit | edit source]

"From 1984 until 1992 [at publication of this text] an endemic period occurred in which an usually large number of cluster and epidemics of M.E./CFS have been recognized in North America. After an apparent initial increase in the morbidity in 1983 there seemed to have appeared in late summer of 1984 an unprecedented increase of sporadic and epidemic cases across North America. Although certain geographical hot spots seen to have taken up much of the medical interest, this endemic situation probably represents an unusual and unremitting morbidity in all areas of the United States and Canada." -Dr. Byron Hyde-

1984 - Incline village, Lake Tahoe, Nevada, USA[edit | edit source]

A chronic illness characterized by fatigue, neurologic and immunologic disorders and active human herpesvirus type 6 infection. This community epidemic apparently started in a girls' basketball team, then involved primarily teachers in at least three high schools, and then large numbers of the community.[7]

Note: This outbreak prompted a Centers for Disease Control response and was the catalyst for the name Chronic fatigue syndrome and the development of the CDC's 1994 research diagnostic tool Fukuda criteria used worldwide.

1984 - Chapel Hill, North Carolina, USA[edit | edit source]

"Epidemic amongst members of The North Carolina Symphony Orchestra. Low NKC [Natural Killer Cells] associated with high yield of lymphoma, astrocytoma, glioma."

All the members of the N.C. Symphony Orchestra, Chapel Hill, NC got sick. Seven remained ill with chronic fatigue as late as 2009.

A series of studies done in 1988 and 1989 by the University of Pittsburgh Cancer Center showed that four of the inflicted NC orchestra members who developed cancer had lower levels of activity of natural killer cells, a type of immune cell that can directly kill cancer.

1984 - Montreal, Quebec-Ontario, Canada[edit | edit source]

Over 500 cases of M.E./CFS documented during August-November 1984 period. This endemic was active in all parts of Canada during this period and appears [to] have maintained its activity until the time of writing in 1991.

1984-85 - Truckee, California, USA[edit | edit source]

M.E. epidemic involving teachers and students. 1984 - 1985: Incline Village Nevada Lake Tahoe outbreak in town and all people vacationing at This resort town.

1985 - Lyndonville, New York, USA[edit | edit source]

M.E. epidemic in a rural community involving children and adults.[7]

1985 Yerington, Nevada, USA[edit | edit source]

In the same area [not far from Truckee, California] an M.E./CFS-like epidemic reputedly occurred in a reservation of American Native people.

1986 - Placerville, California, USA[edit | edit source]

Outbreak of chronic fatigue syndrome 'coincident with a heavy contamination of the local unfiltered water supply'.

1988 - Sonora, California, USA[edit | edit source]

"More than 35 children and adults were diagnosed with M.E. in the mountain country 100 miles from Lake Tahoe. Many of these patients were associated in some way with Columbia Community College."

1988 - Narrabeen, NSW, Australia[edit | edit source]

[5][8]

1989 - Roseville, California, USA[edit | edit source]

Rosedale Hospital reported 11 cases of M.E./CFS among staff.

1990s[edit | edit source]

1990 - Elk Grove, California, USA[edit | edit source]

M.E. epidemic among teachers and students.

1996 - Mohave Valley region, Arizona, USA[edit | edit source]

Over 100 people became ill with a "multi-system stealth virus infection with encephalopathy (MSVIE)." A protracted course followed, with a diverse range of symptoms similar to CFS.[9]

Outbreaks by region[edit | edit source]

North America[edit | edit source]

Canada[edit | edit source]

United States[edit | edit source]

Europe[edit | edit source]

Denmark[edit | edit source]

Germany[edit | edit source]

Greece[edit | edit source]

Iceland[edit | edit source]

Ireland[edit | edit source]

Switzerland[edit | edit source]

United Kingdom[edit | edit source]

Asia[edit | edit source]

Lebanon[edit | edit source]

Africa[edit | edit source]

Sierra Leone[edit | edit source]

South Africa[edit | edit source]

Australia and New Zealand[edit | edit source]

Australia[edit | edit source]

New Zealand[edit | edit source]

Related Lists[edit | edit source]

See also[edit | edit source]

References[edit | edit source]