Jarred Younger

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Doctor Jarred Younger is an American researcher who leads the Neuroinflammation, Pain & Fatigue lab at the University of Birmingham, Alabama, United States. He previously worked at the Stanford ME/CFS Initiative with Jose Montoya, as an Assistant Professor involved in a notable study highlighting leptin levels and ME/CFS.[1] [2]

He is currently funded by the National Institutes of Health and the Department of Defense to study new techniques for diagnosing and treating neuroinflammation in ME/CFS, Fibromyalgia and Gulf War Illness . In particular his work focuses on the role of microglia.

Dr. Younger is a member of the Working Group which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.[3]

Awards[edit | edit source]

Notable studies[edit | edit source]

  • 2017, Cytokine signature associated with disease severity in chronic fatigue syndrome patients[5] (Full Text)
  • 2013, Fibromyalgia Symptoms Are Reduced by Low-Dose Naltrexone: A Pilot Study[6] (Full Text)
  • 2013, Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: Evidence of inflammatory pathology[7] (Full Text)
  • 2010, Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels[8] (Full Text)

Talks & interviews[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

External Links[edit | edit source]

References[edit | edit source]

  1. Stringer, EA; Baker, KS; Carrol, IR; Montoya, JG; Chu, L; Maeker, HT; Younger, JW (April 9, 2013), "Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: Evidence of inflammatory pathology", J Transl Med., doi:10.1186/1479-5876-11-93, PMID 23570606
  2. Pandora Research Report: Jarred Younger - Leptin in the Role of Neuroinflammation, Pain and Fatigue
  3. https://bos.etapestry.com/prod/viewEmailAsPage.do?erRef=773.0.423082047&databaseId=OMF&mailingId=34274682&jobRef=773.0.506425459&key=b6b9237b3ebd1e462a5d11dbc5c4dae&personaRef=773.0.423082048&memberId=1348639685
  4. http://solvecfs.org/2016-ramsay-award-program-results/
  5. Montoya, Jose G.; Holmes, Tyson H.; Anderson, Jill N.; Maecker, Holden T.; Rosenberg-Hasson, Yael; Valencia, Ian J.; Chu, Lily; Younger, Jarred W.; Tato, Cristina M.; Davis, Mark M. (2017), "Cytokine signature associated with disease severity in chronic fatigue syndrome patients", Proceedings of the National Academy of Sciences of the United States of America, 114 (34): E7150-E7158, doi:10.1073/pnas.1710519114
  6. Younger, J., & Mackey, S. (2009). Fibromyalgia Symptoms Are Reduced by Low-Dose Naltrexone: A Pilot Study. Pain Medicine (Malden, Mass.), 10(4), 663–672. http://doi.org/10.1111/j.1526-4637.2009.00613.x
  7. Stringer, E. A., Baker, K. S., Carroll, I. R., Montoya, J. G., Chu, L., Maecker, H. T., & Younger, J. W. (2013). Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathology. Journal of Translational Medicine, 11, 93. http://doi.org/10.1186/1479-5876-11-93
  8. Zinn, Marcie & Zinn, Mark & Jason, Leonard. (2016). Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study. Applied psychophysiology and biofeedback. 41. 10.1007/s10484-016-9331-3.