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Interstitial cystitis
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'''Interstitial cystitis''' or '''IC''' is a bladder condition that usually consists of multiple symptoms such as recurring pelvic pain, pressure, or discomfort in the bladder and pelvic region, and an urgent and frequent need to urinate.<ref>https://www.ichelp.org/about-ic/what-is-interstitial-cystitis/</ref><ref>https://www.health.harvard.edu/diseases-and-conditions/diagnosing-and-treating-interstitial-cystitis</ref> Other names for interstitial cystitis include: painful bladder syndrome (PBS), bladder pain syndrome (BPS), and chronic pelvic pain.<ref>https://www.ichelp.org/diagnosis-treatment/</ref> ==Prevalence== Although no numbers are given, the Interstitial Cystitis Association states on their website that a "small subset of interstitial cystitis (IC) patients" also have chronic fatigue syndrome (CFS).<ref>https://www.ichelp.org/about-ic/associated-conditions/chronic-fatigue-syndrome/</ref> Individuals with ME/CFS had a worse prognosis for their IC symptoms, according to a 2013 study of patients with IC.<ref>https://www.ncbi.nlm.nih.gov/pubmed/22882525</ref> The [[International Consensus Criteria]] for [[myalgic encephalomyelitis]] list interstitial cystitis as a [[comorbidity]] often found in people with ME, and list cystitis as a potential trigger of ME.<ref name="ICP2011primer">{{citation | last1 = Carruthers | first1 = BM | authorlink1 = Bruce Carruthers | last2 = van de Sande | first2 = MI | authorlink2 = Marjorie van de Sande | last3 = De Meirleir | first3 = KL | authorlink3 = Kenny de Meirleir | last4 = Klimas | first4 = NG | authorlink4 = Nancy Klimas | last5 = Broderick | first5 = G | authorlink5 = Gordon Broderick | last6 = Mitchell | first6 = T | authorlink6 = Terry Mitchell | last7 = Staines | first7 = D | authorlink7 = Donald Staines | last8 = Powles | first8 = ACP | authorlink8 = A C Peter Powles | last9 = Speight | first9 = N | authorlink9 = Nigel Speight | last10 = Vallings | first10 = R | authorlink10 = Rosamund Vallings | last11 = Bateman | first11 = L | authorlink11 = Lucinda Bateman | last12 = Bell | first12 = DS | authorlink12 = David Bell | last13 = Carlo-Stella | first13 = N | authorlink13 = Nicoletta Carlo-Stella | last14 = Chia | first14 = J | authorlink14 = John Chia | last15 = Darragh | first15 = A | authorlink15 = Austin Darragh | last16 = Gerken | first16 = A | authorlink16 = Anne Gerken | last17 = Jo | first17 = D | authorlink17 = Daehyun Jo | last18 = Lewis | first18 = DP | authorlink18 = Donald Lewis | last19 = Light | first19 = AR | authorlink19 = Alan Light | last20 = Light | first20 = KC | authorlink20 = Kathleen Light | last21 = Marshall-Gradisnik | first21 = S | authorlink21 = Sonya Marshall-Gradisnik | last22 = McLaren-Howard | first22 = J | authorlink22 = John McLaren-Howard | last23 = Mena | first23 = I | authorlink23 = Ismael Mena | last24 = Miwa | first24 = K | authorlink24 = Kunihisa Miwa | last25 = Murovska | first25 = M | authorlink25= Modra Murovska | last26 = Stevens | first26 = SR | authorlink26 = Staci Stevens | title = Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners | date = 2012 | isbn = 978-0-9739335-3-6 | pages =8, 12 | url = http://www.investinme.org/Documents/Guidelines/Myalgic%20Encephalomyelitis%20International%20Consensus%20Primer%20-2012-11-26.pdf }}</ref> The [[Canadian Consensus Criteria]] for ME/CFS also lists IC as a comorbidity.<ref name="canadianconsensus">{{Citation | last1 = Carruthers | first1 = Bruce M. | authorlink1 = Bruce Carruthers | last2 = Jain | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain | last3 = De Meirleir | first3 = Kenny L. | authorlink3 = Kenny De Meirleir | last4 = Peterson | first4 = Daniel L. | authorlink4 = Daniel Peterson | last5 = Klimas | first5 = Nancy G. | authorlink5 = Nancy Klimas | last6 = Lerner | first6 = A. Martin | authorlink6 = Martin Lerner | last7 = Bested | first7 = Alison C. | authorlink7 = Alison Bested | last8 = Flor-Henry | first8 = Pierre | authorlink8 = Pierre Flor-Henry | last9 = Joshi | first9 = Pradip | authorlink9 = Pradip Joshi | last10 = Powles | first10 = AC Peter | authorlink10 = A C Peter Powles | last11 = Sherkey | first11 = Jeffrey A. | authorlink11 = Jeffrey Sherkey | last12 = van de Sande | first12 = Marjorie I. | authorlink12 = Marjorie van de Sande | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols | journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | date = 2003 | pmid = | doi = 10.1300/J092v11n01_02 | pages=13 | url = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf }}</ref> ==Possible causes== No one knows the exact cause of IC. Bladder wall abnormalities exist in people with IC, but it's not clear whether these are the cause of the condition or the result of some other underlying process.<ref>https://www.health.harvard.edu/diseases-and-conditions/diagnosing-and-treating-interstitial-cystitis</ref> ==Notable studies== *2013, Prognostic factors for recent-onset interstitial cystitis/painful bladder syndrome<ref>https://www.ncbi.nlm.nih.gov/pubmed/22882525</ref> ==See also== *[[Urinary frequency]] *[[Sympathetic nervous system]] *[[Dysautonomia]] *[[Pain]] ==Learn more== *[https://www.ichelp.org/ Interstitial Cystitis Association] ==References== {{reflist}} [[Category:Signs and symptoms]] [[Category:Genitourinary signs and symptoms]] [[Category:Genitourinary diseases and disorders]] [[Category:Potential comorbidities]] [[Category:Diagnoses]]
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