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Interferon gamma inducible protein 10
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{{stub}} IP-10 is [[Interferon gamma|Interferon gamma (INF-Ξ³) inducible protein]] 10, and is also known as '''C-X-C Motif Chemokine Ligand 10''' or '''CXCL10'''.<ref name="uniprot" /> IP-10 is a [[chemokine]], and important for recruiting [[Natural killer cell|natural killer cells]] to the myocardium, and for limiting viral duplication in murine (mice/rodent) [[coxsackievirus]] infection.<ref name="Loux2001">{{Cite book | last = Loux | first = Tara J. | last2 = Lotze | first2 = Michael T. | last3 = Zeh | first3 = Herbert J. | date = 2010-01-01|editor-last = Lotze|editor-first = Michael T.|editor2-last = Thomson|editor2-first = Angus W. | title = Chapter Fourteen - NK cells as recipients of cytokine signals | url = http://www.sciencedirect.com/science/article/pii/B9780123704542000144|location=San Diego|publisher=Academic Press|pages=189β201|isbn=9780123704542}}</ref> === Alternative names === IP-10 is also known as: * CXCL10<ref name="uniprot">{{Cite web | url = https://www.uniprot.org/uniprot/P02778 | title = CXCL10 - C-X-C motif chemokine 10 precursor - Homo sapiens (Human) - CXCL10 gene & protein | website = uniprot.org|access-date=2019-01-24}}</ref> * C-X-C motif [[chemokine]] 10<ref name="uniprot" /> * [[Interferon gamma|IFN-Ξ³]] inducible protein 10<ref name="Loux2001" /> * [[Interferon gamma]] inducible protein 10 * 10 kDa interferon-gamma induced protein<ref>{{Cite book | date = 2013-01-01|editor-last = Lee|editor-first = James J.|editor2-last = Rosenberg|editor2-first = Helene F. | title = Chapter 6 - Eosinophil Trafficking | url =http://www.sciencedirect.com/science/article/pii/B9780123943859000067|location=Boston|publisher=Academic Press|pages=121β166|isbn=9780123943859 | last = | first = |journal=Eosinophils in Health and Disease|issue=|quote=|via=|volume=}}</ref> ==Function== ==ME/CFS== ==Notable studies == * 2017 - The Role of [[IP-10]] in Chronic Fatigue Syndrome<ref>{{Cite journal | last = McArdle | first = Anne | authorlink = Anne McArdle | last2 = Gusnanto | first2 = Arief | last3 = Earl | first3 = Kate | last4 = Sakellariou | first4 = George | last5 = Lawton | first5 = Clare | last6 = Owens | first6 = Daniel | last7 = Close | first7 = Graeme | last8 = Beadsworth | authorlink8 = Mike Beadsworth | first8 = Michael | last9 = Dye | first9 = Louise | date = 2017-04-01 | title = The role of IP-10 in Chronic Fatigue Syndrome. | url = https://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.lb789|journal=The FASEB Journal|language=en|doi=10.1096/fasebj.31.1_supplement.lb789|issue=1 supplement|pages=lb789|volume=1|quote=|via=}}</ref> :''This study found "compelling evidence" of the role of several [[cytokine]]s/[[chemokine]]s in the physiological and cognitive pathology in a group of patients with [[chronic fatigue syndrome]], although these patients were selected using the [[Oxford criteria]], which includes many patients with [[chronic fatigue]] not caused by ME/CFS.'' ==Learn more == *[https://www.genecards.org/cgi-bin/carddisp.pl?gene=CXCL10 C-X-C Motif Chemokine Ligand 10] - Gene cards ==See also == *[[IFN-Ξ³]] *[[Interferon]] *[[Natural killer cell]]s *[[Chemokine]] ==References == {{Reflist}} [[Category:Proteins]] [[Category:Cytokines]] [[Category:Chemokines]]
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