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Immunoglobulin M
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'''Immunoglobulin M''' or '''IgM''' is a basic antibody that is produced by [[B cell]]s.<ref name="21-keyterms">{{Cite book |chapter-url=https://openstax.org/books/anatomy-and-physiology/pages/21-key-terms | url=https://openstax.org/books/anatomy-and-physiology/pages/1-introduction | title = Anatomy and Physiology | last = Betts | first = JG | authorlink = | last2 = Young | first2 = KA | authorlink2 = | last3 = Wise | first3 = JA | last4 = Johnson | first4 = E | last5 = Poe | first5 = B | last6 = Kruse | first6 = DH | last7 = Korol | first7 = O | last8 = Johnson | first8 = JE | last9 = Womble | first9 = M | last10 = DeSaix | first10 = P | date = Apr 23, 2013 | website = OpenStax|location=Houston, Texas|language=en|archive-url=|archive-date=|url-status=|access-date=2021-10-20|chapter=Key Terms}}</ref> ==Function== ==ME/CFS== One study found elevated blood serum concentrations of both [[IgA]] and IgM to [[lipopolysaccharides]] of [[gram-negative bacteria]]. Serum IgA levels correlated with illness severity as measured by the [[FibroFatigue scale]].<ref>{{Cite journal | last = Maes | first = Michael | authorlink = Michael Maes | last2 = Mihaylova | first2 = Ivana | authorlink2 = | last3 = Leunis | first3 = Jean-Claude | authorlink3 = | date = Apr 2007 | title = Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability | url = https://pubmed.ncbi.nlm.nih.gov/17007934/|journal=Journal of Affective Disorders|volume=99|issue=1-3 | pages = 237β240|doi=10.1016/j.jad.2006.08.021|issn=0165-0327|pmc=|pmid=17007934|access-date=|quote=|via=}}</ref> ==See also== *[[Immunoglobulin A]] *[[Intravenous immunoglobulin]] ==Learn more== *[https://openstax.org/books/anatomy-and-physiology/pages/21-4-the-adaptive-immune-response-b-lymphocytes-and-antibodies The Adaptive Immune Response: B-lymphocytes and Antibodies] ==References== {{reflist}} [[Category:Antibodies]] [[Category:Immunology]] [[Category:Biochemistry and cell biology]] [[Category:Glycoproteins]]
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