How have selection bias and disease misclassification undermined the validity of myalgic encephalomyelitis/chronic fatigue syndrome studies?

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How have selection bias and disease misclassification undermined the validity of myalgic encephalomyelitis/chronic fatigue syndrome studies? is a paper that compares the selection criteria of the Oxford criteria (OC) and the Canadian Consensus Criteria (CCC) noting that for every 15 patients selected under the Oxford criteria there are 14 false positives when compared to CCC.[1]

The authors suggest that in a clinical setting SEID criteria from the Institute of Medicine report or the Fukuda criteria (CDC- 1994) can be used to diagnose patients and then those selected can be used in research.

Notable studies using Oxford criteria[edit | edit source]

PACE trial


References[edit | edit source]