Histamine

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Histamine is a compound involved in local immune responses, regulates the gut, and acts as a neurotransmitter.

Type of histamine receptors[edit | edit source]

Role of histamine in the body[edit | edit source]

Histamine causes the release of nitric oxide, which in turn causes vasodilation. [1]

Modulating histamine levels[edit | edit source]

Histamine is broken down by an enzyme called diamine oxidase (DAO), which is found mainly in the gastrointestinal tract and in pregnant women, the placenta. Nutritional deficiencies in magnesium, Vitamin B6 and copper can decrease DAO activity.

Vitamin C reduces blood histamine levels.[2][3]

Manganese and zinc can prevent the release of histamine from mast cells.

Histamine intolerance[edit | edit source]

Histamine intolerance can be a sign of mast cell activation disorder.

See also[edit | edit source]

References[edit | edit source]

  1. ↑ Reference needed
  2. ↑ http://jn.nutrition.org/content/110/4/662.full.pdf
  3. ↑ http://www.ncbi.nlm.nih.gov/pubmed/1578094

enzyme a substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.

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