Hashimoto's thyroiditis (hypothyroidism): Difference between revisions
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== HLA risk alleles link ME/CFS and Hashimoto's == | == HLA risk alleles link ME/CFS and Hashimoto's == | ||
In a large 2020 study, CFS patients with [[Human leukocyte antigen genes|Human Leukocyte Antigen]] (HLA) risk alleles were found to share the following [[Autoimmune disease|autoimmune diseases]], ordered by frequency: | In a large 2020 study, CFS patients with [[Human leukocyte antigen genes|Human Leukocyte Antigen]] (HLA) risk alleles were found to share the following [[Autoimmune disease|autoimmune diseases]], ordered by frequency:{{Citation needed}} | ||
# [[Hashimoto's thyroiditis]]/hypothyreosis, | # [[Hashimoto's thyroiditis]]/hypothyreosis, | ||
# Psoriasis | # Psoriasis | ||
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|'''Association of active human herpesvirus-6 (HHV-6) infection with autoimmune thyroid gland diseases''' | |'''Association of active human herpesvirus-6 (HHV-6) infection with autoimmune thyroid gland diseases''' | ||
A Sultanova, M Cistjakovs, S Gravelsina, S Chapenko, S Roga, E Cunskis, Z Nora-Krukle, V Groma, I Ventina, M Murovska<ref>{{Cite journal|last=Sultanova|first=A.|last2=Cistjakovs|first2=M.|last3=Gravelsina|first3=S.|last4=Chapenko|first4=S.|last5=Roga|first5=S.|last6=Cunskis|first6=E.|last7=Nora-Krukle|first7=Z.|last8=Groma|first8=V.|last9=Ventina|first9=I.|date=2017 | A Sultanova, M Cistjakovs, S Gravelsina, S Chapenko, S Roga, E Cunskis, [[Zaiga Nora-Krukle|Z Nora-Krukle]], V Groma, I Ventina, [[Modra Murovska|M Murovska]]<ref>{{Cite journal|last=Sultanova|first=A.|last2=Cistjakovs|first2=M.|last3=Gravelsina|first3=S.|last4=Chapenko|first4=S.|last5=Roga|first5=S.|last6=Cunskis|first6=E.|last7=Nora-Krukle|first7=Z.|authorlink7=Zaiga Nora-Krukle|last8=Groma|first8=V.|last9=Ventina|first9=I.|last10=Murovska|first10=M.|authorlink10=Modra Murovska|date=Jan 2017|title=Association of active human herpesvirus-6 (HHV-6) infection with autoimmune thyroid gland diseases|url=https://pubmed.ncbi.nlm.nih.gov/27693656/|journal=Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases|volume=23|issue=1|pages=50.e1–50.e5|doi=10.1016/j.cmi.2016.09.023|issn=1469-0691|pmid=27693656}}</ref> | ||
|2017 | |2017 | ||
|A study comparing the involvement of HHV-6 infection between autoimmune thyroiditis (AIT) patients and healthy controls. Thyroid gland biopsies confirmed active persistent HHV-6 infection in 18 of 44 (41%) AIT patients and 1 of 17 (6%) healthy controls. | |A study comparing the involvement of HHV-6 infection between autoimmune thyroiditis (AIT) patients and healthy controls. Thyroid gland biopsies confirmed active persistent HHV-6 infection in 18 of 44 (41%) AIT patients and 1 of 17 (6%) healthy controls. | ||
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==See also== | ==See also== | ||
* [[Autoimmune disease]] | |||
* [[Female predominant diseases]] | * [[Female predominant diseases]] | ||
* [[Hypothyroidism]] | * [[Hypothyroidism]] | ||
==Learn more== | ==Learn more== | ||
*[http://www.thyroiduk.org.uk/tuk/about_the_thyroid/hashimotos.html Hashimoto's] - Thyroid UK | *[http://www.thyroiduk.org.uk/tuk/about_the_thyroid/hashimotos.html Hashimoto's] - Thyroid UK | ||
==References== | ==References== | ||
{{reflist}} | |||
[[Category:Diagnoses]] | [[Category:Diagnoses]] | ||
[[Category:Potential comorbidities]] | [[Category:Potential comorbidities]] | ||
[[Category:Thyroid diseases]] | [[Category:Thyroid diseases]] | ||
Revision as of 13:13, August 24, 2020
 | This article is a stub. |
Hashimoto's thyroiditis, also known as Hashimoto's disease, is an autoimmune disease affecting thyroid function.
Signs and symptoms[edit | edit source]
Treatments[edit | edit source]
HLA risk alleles link ME/CFS and Hashimoto's[edit | edit source]
In a large 2020 study, CFS patients with Human Leukocyte Antigen (HLA) risk alleles were found to share the following autoimmune diseases, ordered by frequency:[citation needed]
- Hashimoto's thyroiditis/hypothyreosis,
- Psoriasis
- Rheumatoid arthritis
- Alopecia areata
- Crohn’s disease or ulcerative colitis
Hashimoto's thyroiditis viral infections commonly associated with ME/CFS[edit | edit source]
Studies suggesting a viral trigger for Hashimoto's thyroiditis and autoimmune thyroiditis (AIT) that are also viruses commonly associated with ME/CFS.
| Virologic and Immunologic Evidence Supporting an Association between HHV-6 and Hashimoto's Thyroiditis
Elisabetta Caselli, Maria Chiara Zatelli, Roberta Rizzo, Sabrina Benedetti, Debora Martorelli, Giorgio Trasforini, Enzo Cassai, Ettore C. degli Uberti, Dario Di Luca, Riccardo Dolcetti[1] |
2012 | Study using fine needle aspirates (FNA) thyroid biopsies found HHV-6 DNA in 28 of 34 (82%) Hashimoto's thyroiditis patients and 3 of 28 (10%) controls. |
| Association of active human herpesvirus-6 (HHV-6) infection with autoimmune thyroid gland diseases
A Sultanova, M Cistjakovs, S Gravelsina, S Chapenko, S Roga, E Cunskis, Z Nora-Krukle, V Groma, I Ventina, M Murovska[2] |
2017 | A study comparing the involvement of HHV-6 infection between autoimmune thyroiditis (AIT) patients and healthy controls. Thyroid gland biopsies confirmed active persistent HHV-6 infection in 18 of 44 (41%) AIT patients and 1 of 17 (6%) healthy controls. |
| Study of Epstein–Barr virus serological profile in Egyptian patients with Hashimoto’s thyroiditis: A case-control study
Samir Naeim Assaad, Marwa Ahmed Meheissen, Eman Tayae Elsayed, Saher N. Alnakhal, Tarek M. Salema[3] |
2020 | This study included 60 Hashimoto's thyroiditis patients and 60 healthy controls. Epstein-Barr virus (EBV) Early Antigen (EA) was positive in 20 of 60 (33%) HT patients and 4 of 60 (7%) healthy controls, indicating a higher prevalence of active EBV in Hashimoto patients. |
See also[edit | edit source]
Learn more[edit | edit source]
- Hashimoto's - Thyroid UK
References[edit | edit source]
- ↑ Caselli, Elisabetta; Zatelli, Maria Chiara; Rizzo, Roberta; Benedetti, Sabrina; Martorelli, Debora; Trasforini, Giorgio; Cassai, Enzo; degli Uberti, Ettore C.; Di Luca, Dario (October 4, 2012). "Virologic and Immunologic Evidence Supporting an Association between HHV-6 and Hashimoto's Thyroiditis". PLoS Pathogens. 8 (10). doi:10.1371/journal.ppat.1002951. ISSN 1553-7366. PMC 3464215. PMID 23055929.
- ↑ Sultanova, A.; Cistjakovs, M.; Gravelsina, S.; Chapenko, S.; Roga, S.; Cunskis, E.; Nora-Krukle, Z.; Groma, V.; Ventina, I.; Murovska, M. (January 2017). "Association of active human herpesvirus-6 (HHV-6) infection with autoimmune thyroid gland diseases". Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 23 (1): 50.e1–50.e5. doi:10.1016/j.cmi.2016.09.023. ISSN 1469-0691. PMID 27693656.
- ↑ Assaad, Samir Naeim; Meheissen, Marwa Ahmed; Elsayed, Eman Tayae; Alnakhal, Saher N.; Salem, Tarek M. (March 12, 2020). "Study of Epstein–Barr virus serological profile in Egyptian patients with Hashimoto's thyroiditis: A case-control study". Journal of Clinical & Translational Endocrinology. 20. doi:10.1016/j.jcte.2020.100222. ISSN 2214-6237. PMC 7090364. PMID 32215255.
